Results 21 to 30 of about 4,502 (179)

The Pyroglutamate Hydantoin Rearrangement [PDF]

European Journal of Organic Chemistry, 2006
Abstract When a mixture of a pyroglutamate and an isocyanate in THF is treated with NaH, a ring transformation occurs leading to functionalised hydantoins. The novel reaction involves a ring‐closing ring‐opening sequence providing a new and straightforward access to an interesting class of heterocyclic compounds. Furthermore, starting
Nicolai Dieltiens, Diederica D. Claeys, Viktor V. Zhdankin, Victor N. Nemykin, Bart Allaert, Francis Verpoort, Christian V. Stevens   +6 more
openaire   +1 more source

Structural Control of Dual Emission in Coumarin Fluorophores for Visualizing Protein Droplet Maturation

Angewandte Chemie, EarlyView.
A coumarin‐based dual‐emission fluorophore was designed to visualize the maturation of protein liquid droplets. Upon covalent conjugation to droplet‐forming proteins, ratiometric fluorescence imaging allowed real time monitoring of droplet maturation. This probe is applicable to the analysis of droplet formation and maturation mechanisms, as well as to
Tomoya Yamamoto, Yusei Otsuka, Asuka Mori, Yuichiro Hori, Yuma Yamamoto, Motonari Uesugi, Kazuya Kikuchi   +6 more
wiley   +2 more sources

Investigation of the GnRH antagonist degarelix isomerization in biological matrices

Pharmacology Research & Perspectives, 2023
One of the main objectives of peptide drug design is the improvement of peptide pharmacokinetics with maintaining biological activity, which can be achieved by the complex modifications of the primary structure of the peptides.
Lucia Ferrazzano, Alessandra Tolomelli, Ivan Guryanov, Marco Macis, Ulrich Abel, Antonio Ricci, Walter Cabri   +6 more
doaj   +1 more source

SYNTHESIS AND CHARACTERIZATION OF COMPLEX DIAQUADIHYDANTOIN NICKEL(II) SULFAT MONOHIDRAT)

Alchemy, 2016
The purpose of the research is to find out the synthesis, formula and characteristic of complex of Nickel(II) with hydantoin (hyd). Complex of nickel(II) with hydantoin have been synthesized in 1 : 1 mole ratio of metal to ligan in methanol.The formula
Sentot Budi Rahardjo, Surya Dewi Marliyana, Nur Asih Siwi Wulandari   +2 more
doaj   +1 more source

Drug-Induced Changes in the Gingival Tissue

Journal of Interdisciplinary Medicine, 2023
Drug-induced gingivitis is caused by the administration of certain drugs such as hydantoin, calcium blockers, beta-blockers, cyclosporine, and oral contraceptives.
Kis Estella, Lazăr Ana, Lazăr Luminița   +2 more
doaj   +1 more source

HYDANTOIN TETRAZONES. [PDF]

Journal of the American Chemical Society, 1908
n ...
openaire   +2 more sources

12-Tungstophosphoric acid–1,1′-methylenebis(imidazolidine-2,4-dione)–imidazolidine-2,4-dione–water (2/1/4/21.5)

Acta Crystallographica Section E, 2010
In the asymmetric unit of the title organic–inorganic hybrid material, 2{H3[PW12O40]}·4C3H4N2O2·C7H8N4O4·21.5H2O, there are four crystallographically independent hydantoin molecules, one dimerized hydantoin molecule ...
Mohammad Hasan Alizadeh, Irandokht Mohammadi Zonoz   +1 more
doaj   +1 more source

Synthesis of series of different imidazolidine-2,4-dione derivatives and evaluation of their antimicrobial potential [PDF]

Kragujevac Journal of Science, 2022
A series of twenty two different imidazolidine-2,4-dione derivatives, divided according to their structure into five groups, including alkyl, alkenyl or aryl 5,5disubstituted hydantoins, spirohydantoins, and fused bicyclic and tricyclic hydantoins, was ...
Šmit Biljana, Radojević Ivana, Stanić Petar B., Ašanin Darko, Vasić Marijana, Katanić-Stanković Jelena S.   +5 more
doaj   +1 more source

Microwave Assisted Synthesis of Novel Functionalized Hydantoin Derivatives and Their Conversion to 5-(Z) Arylidene-4H-imidazoles

Molecules, 2011
2-(Alkyl-1-yl)-1H-imidazol-5(4H)-ones 5a–n were synthesized via nucleophilic substitution of the methylsulfanyl group of the corresponding 2-(methylthio)-1H-imidazol-5(4H)-ones 3a–c with suitably substituted secondary amines.
Edward R. Biehl, Haribabu Ankati, Sukanta Kamila   +2 more
doaj   +1 more source

The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
The clinically used antibiotic Furagin and its derivatives possess inhibitory activity on human (h) carbonic anhydrases (CA, EC 4.2.1.1), some of which are highly expressed in various tissues and malignancies (hCA IX/XII).
Aleksandrs Pustenko, Alessio Nocentini, Paola Gratteri, Alessandro Bonardi, Igor Vozny, Raivis Žalubovskis, Claudiu T. Supuran   +6 more
doaj   +1 more source