Results 11 to 20 of about 22,486 (258)

Orogenital ulcers, SLE and hydralazine [PDF]

Postgraduate Medical Journal, 1981
Summary The case is reported of a man developing drug-induced systemic lupus erythematosus while taking hydralazine. The illness was characterized by arthritis and a purpuric rash particularly in the light-sensitive areas as well as orogenital and cutaneous ulceration. Anti-nuclear antibody and DNA binding were positive.
R. A. L. Brewis, P. Y. Graham, E. Neville   +2 more
openaire   +4 more sources

Hydralazine-Induced ANCA Vasculitis Presenting With Pericarditis: A Novel Case and Literature Review. [PDF]

Case Rep Cardiol
Hydralazine, a commonly used arterial vasodilator for managing congestive heart failure and hypertension, is known to be associated with drug-induced lupus and, less frequently, antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). Drug-
Hammami AS, Oriaifo O, Hidri S, Singh S, El Sharu H, Peltz J, Nomigolzar S, Udani K.   +7 more
europepmc   +2 more sources

Hydralazine augmented ultrasound hyperthermia for the treatment of hepatocellular carcinoma

Scientific Reports, 2021
This study investigates the use of hydralazine to enhance ultrasound hyperthermia for the treatment of hepatocellular carcinoma (HCC) by minimizing flow-mediated heat loss from the tumor.
Mrigendra B. Karmacharya, Laith R. Sultan, Stephen J. Hunt, Chandra M. Sehgal   +3 more
doaj   +1 more source

Novel Role of Gestational Hydralazine in Limiting Maternal and Dietary Obesity-Related Chronic Kidney Disease

Frontiers in Cell and Developmental Biology, 2021
BackgroundMaternal obesity is a risk factor for chronic kidney disease (CKD) in offspring, underpinning the theory of the developmental origins of health and disease.
Benjamin P. Larkin, Long T. Nguyen, Miao Hou, Sarah J. Glastras, Sarah J. Glastras, Hui Chen, Rosy Wang, Carol A. Pollock, Sonia Saad, Sonia Saad   +9 more
doaj   +1 more source

Potential Impacts of Hydralazine as a Novel Antioxidant on Cardiovascular and Renal Disease—Beyond Vasodilation and Blood Pressure Lowering

Antioxidants, 2022
Hydralazine is a traditional antihypertensive drug that was developed several decades ago. Its most well-known effect is blood pressure lowering by arterial vasodilation.
Ting-Ting Chang, Jaw-Wen Chen
doaj   +1 more source

The alteration of neuronal activities of the cuneiform nucleus in non-hypovolemic and hypovolemic hypotensive conditions

Arquivos de Neuro-Psiquiatria, 2021
Background: The cuneiform nucleus is located in the center of the circuit that mediates autonomic responses to stress. Hemorrhagic hypotension leads to chemoreceptor anoxia, which consequently results in the reduction of baroreceptor discharge and ...
Reza Mohebbati, Hassan Abbassian, Mohammad Naser Shafei, Ali Gorji, Sajad Sahab Negah   +4 more
doaj   +1 more source

Overlapping Syndromes: Drug-Induced Vasculitis From Hydralazine With Positive Antinuclear Antibodies

Clinical Medicine Insights: Case Reports, 2023
Hydralazine is an antihypertensive medication that has been associated with drug-associated autoimmune syndromes like interstitial lung disease, pauci-immune glomerulonephritis, and hypocomplementemia.
Lakshmi Kannan, UmmeRubab Syeda
doaj   +1 more source

Hydralazine Associated With Reduced Therapeutic Phlebotomy Frequency in a Nationwide Cohort Study: Real-World Effectiveness for Drug Repurposing

Frontiers in Pharmacology, 2022
Background: Therapeutic phlebotomy, known as scheduled bloodletting, has been the main method for managing erythrocytosis symptoms and thrombocytosis-associated complications in various blood disorders.
Wei-Zhi Lin, Chi-Hsiang Chung, Chi-Hsiang Chung, Chi-Hsiang Chung, Chia-Yang Shaiu, Chia-Yang Shaiu, Bing-Heng Yang, Bing-Heng Yang, Wu-Chien Chien, Wu-Chien Chien, Wu-Chien Chien, Wu-Chien Chien   +11 more
doaj   +1 more source

Effect of the cholinergic system of the lateral periaqueductal gray (lPAG) on blood pressure and heart rate in normal and hydralazine hypotensive rats [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): Due to the presence of the cholinergic system in the lateral periaqueductal gray (lPAG) column, the cardiovascular effects of Acetylcholine (ACH) and its receptors in normotensive and hydralazine (HYD) hypotensive rats in this area were ...
Atiyeh Ghorbani, Reza Mohebbati, Alireza Rahimi, Vida Alikhani, Mohammad Naser Shafei   +4 more
doaj   +1 more source

Comparison of the Efficacy of Nifedipine and Hydralazine in Hypertensive Crisis in Pregnancy [PDF]

Acta Medica Iranica, 2011
Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy. Oral nifedipine is an alternative in management of these patients.
Zahra Rezaei, Fatemeh Rahimi Sharbaf, Mino Pourmojieb, Yashar Youefzadeh-Fard, Manijeh Motevalian, Zahra Khazaeipour, Sara Esmaeili   +6 more
doaj   +1 more source