Results 41 to 50 of about 31,338 (264)
Cancer Cell International, 2006 Background Among the epigenetic alterations occurring in cancer, DNA hypermethylation and histone hypoacetylation are the focus of intense research because their pharmacological inhibition has shown to produce antineoplastic activity in a variety of ...
Candelaria Myrna +11 more
doaj +1 more source
Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]
, 2014 Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad +6 more
core +2 more sources
Genotype-Guided Hydralazine Therapy
American Journal of Nephrology, 2020 Background: Despite its approval in 1953, hydralazine hydrochloride continues to be used in the management of resistant hypertension, a condition frequently managed by nephrologists and other clinicians.
Kimberly S. Collins +6 more
semanticscholar +1 more source
Variations in Arterial Blood Pressure after Kidney Transplantation [PDF]
, 1973 The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients.
CORMAN, JACQUES L +7 more
core +1 more source
In-vitro study of the effect of anti-hypertensive drugs on placental hormones and angiogenic proteins synthesis in pre-eclampsia [PDF]
, 2014 Antihypertensive drugs lower the maternal blood pressure in pre-eclampsia (PE) by direct or central vasodilatory mechanisms but little is known about the direct effects of these drugs on placental ...
Gangooly, S +2 more
core +4 more sources
Current Cardiology Reviews, 2020 Hydralazine, an arterial vasodilator, is a widely used medication for the management of hypertension and heart failure, especially for patients who cannot tolerate the use of ACEIs or ARBs.
Karim Doughem +6 more
semanticscholar +1 more source
Journal of Pharmacological Sciences, 2021 In the present study, we investigated the renoprotective effects of long-term treatment with yohimbine, an α2-adrenoceptor inhibitor, in a 5/6 nephrectomy-induced chronic kidney disease (CKD) rat model.
Kohei Hayashi +3 more
doaj +1 more source
Linking FHIR-Based Medication Data to a Computable Algorithm for Heart Medication Optimization: A Critical Component of Any Medication Learning Health System. [PDF]
Learn Health SystABSTRACT Introduction Despite strong evidence supporting guideline‐directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF), a significant gap persists in the consistent application of these therapies. This shortfall has prompted organizations like the American College of Cardiology to recommend leveraging electronic ...
LeGrand J +5 more
europepmc +2 more sources
Indian Journal of Rheumatology, 2019 Vascular injury due to drugs is recognized as a distinct entity under the Chapel Hill Consensus Conference 2012 definitions for vasculitis. Drug-induced vasculitis (DIV) may affect various types of vessels.
Durga Prasanna Misra +2 more
doaj +1 more source
His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]
, 1988 The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M. +3 more
core +1 more source