Results 21 to 30 of about 66,186 (324)
Acta Crystallographica Section E: Crystallographic Communications, 2022 In the molecule of the title compound, C9H11N5O2, the oxime and hydrazide groups are situated in a cis-position in relation to the C—C bond linking the two functional groups.
Maksym O. Plutenko +4 more
doaj +1 more source
Molecules, 2015 New series of hydrazones 5–18 were synthesized, in good yields, by reacting 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbohydrazide with differently substituted benzaldehyde.
Cristina Nastasă +4 more
doaj +1 more source
Injectable Dual-Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration. [PDF]
Adv Healthc MaterInjectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Randhawa GK +6 more
europepmc +2 more sources
Synthesis of indoles via alkylidenation of acyl hydrazides [PDF]
, 2009 Indoles have been synthesised via alkylidenation of acyl phenylhydrazides using phosphoranes and the Petasis reagent, followed by in situ thermal rearrangement of the product enehydrazines.
Commeureuc, A.G.J. +5 more
core +1 more source
Crystal structure of 2-cyano-N′-(cyclohexylidene)acetohydrazide
Acta Crystallographica Section E, 2014 In the title compound, C9H13N3O, the cyclohexylidene ring adopts a chair conformation and the bond-angle sum at the C atom linked to the N atom is 359.6°. The cyanoacetohydrazide grouping is close to planar (r.m.s. deviation for the non-H atoms = 0.031 Å)
William T. A. Harrison +4 more
doaj +1 more source
Human Proteoglycan Linkage Region Glycosyltransferases are Dimeric and Show Unexpected Specificities. [PDF]
Angew Chem Int Ed EnglNon‐canonical glycopeptides of the proteoglycan linkage region are accessible by the enzymes B3GalT6 and GlcAT‐1 confirming a recently discovered rescue mode in glycosaminoglycan (GAG) biosynthesis. The crystal structure of B3GalT6 revealed a covalent dimer linked by a disulfide. Abstract We selected the N,O‐glycosylated proteoglycan bikunin as a model
Weidler S +16 more
europepmc +3 more sources
A designed phenylalanyl-tRNA synthetase variant allows efficient in vivo incorporation of aryl ketone functionality into proteins [PDF]
, 2002 Incorporation of non-natural amino acids into proteins in vivo expands the scope of protein synthesis and design. p-Acetylphenylalanine was incorporated into recombinant dihydrofolate reductase (DHFR) in Escherichia coli via a computationally designed ...
Carrico, Isaac S. +4 more
core +2 more sources
Molecules, 2015 We present a trifunctional scaffold designed for the solid-phase synthesis of trimodal compounds. This scaffold holds two alkyne arms in a free and TIPS-protected form for consecutive CuAAC (copper(I)-catalyzed azide–alkyne cycloaddition), one Fmoc ...
Benjamin Fabre +4 more
doaj +1 more source
Molecules, 2020 A novel series of some hydrazones bearing thiazole moiety were generated via solvent-drop grinding of thiazole carbohydrazide 2 with various carbonyl compounds.
Sraa Abu-Melha +5 more
doaj +1 more source
Novel Indole-Based Analogs of Melatonin: Synthesis and in Vitro Antioxidant Activity Studies
Molecules, 2010 The aim of this study was to synthesize and examine possible in vitro antioxidant effects of indole-based melatonin analogue compounds. As a part of our ongoing study nineteen indole hydrazide/hydrazone derivatives were synthesized, characterized and ...
Hanif Shirinzadeh +4 more
doaj +1 more source