Results 121 to 130 of about 18,659 (282)
Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Gurpreet Kaur Randhawa +6 more
wiley +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
6-Amidinopurines as convenient precursors to pyrimido[5,4-d]pyrimidines for sar studies on Mycobacterium tuberculosis [PDF]
, 2012 Thanks are due to University of Minho and Fundação para a Ciência e Tecnologia for financial support (project nºF-COMP-01-0124-FEDER-022716 (ref. FCT PEst-/QUI/UI0686/2011) FEDER-COMPETE, FCT-Portugal and PhD grant awarded to Ana Bacelar SRFH/BD/24959 ...
Bacelar, Ana Helena Dias +4 more
core
The Space Within: How Architected Voids Promote Tissue Formation
Advanced Materials, Volume 38, Issue 7, 2 February 2026.This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools
Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.This review presents the latest advances in the development of ruthenium complexes within the field of protein science, highlighting their potential applications in biomedical and bioanalytical fields. Abstract Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years,
Liyan Zhang, Yun Chen, Sylvestre Bonnet
wiley +2 more sources
e0118 The myeloperoxidase inhibitor, aminobenzoic acid hydrazide, alters neutrophil-endothelial cell interaction [PDF]
, 2010 Li‐Li Hong +7 more
openalex +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue +13 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.A bench‐stable boryl thianthrenium dication is synthesized via thianthrenation of vinyl MIDA boronate. This novel dication enables metal‐free, chemo‐, and diastereoselective late‐stage aziridination with diverse nitrogen nucleophiles. The strategic significance is further showcased by one‐pot electrochemical and asymmetric protocols and versatile ...
Veerabhadra R. Vulupala +7 more
wiley +2 more sources
Microwave Irradiation Promoted Reactions of Orthoesters with Carboxylic Acid Hydrazides. Preparation of 1,3,4-Oxadiazoles [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1997 Rapid and highly efficient synthesis of 2- or 2,5-substituted 1,3,4-oxadiazoles by the condensation of aryl carboxylic acid hydrazides and orthoesters can be achieved under microwave irradiation using an unmodified commercial over in unsealed vessels.
Mohammad Sadegh Khajavi +2 more
doaj
Biomedical Chromatography, Volume 40, Issue 2, February 2026.ABSTRACT Antibody‐drug conjugates (ADCs) are innovative drugs composed of cytotoxic molecules (payload) linked to antibodies, that selectively target and kill cancer cells upon internalization. In vivo, ADCs exist as intact molecules, naked antibodies, or released, unconjugated (linker‐)payload.
Pauline L. M. Buitelaar +4 more
wiley +1 more source