Results 31 to 40 of about 9,447 (241)
Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations
Angewandte Chemie, EarlyView.The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach +4 more
wiley +2 more sources
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017 Aim. Analysis of the scientific literature over the past decade has shown that large synthetic possibilities towards creating new and effective drug substances have heterocyclic compounds, in particular the derivatives of 1,2,4-triazole.
O. A. Suhak +2 more
doaj +1 more source
Acta Chimica Slovenica, 2021 The synthesis of hydrazides formed by quinazolin-4(3H)-ylidenehydrazine and dicarboxylic acids, as well as their further modification are described in the present manuscript.
Nataliia Krasovska +5 more
doaj +1 more source
Results in Chemistry, 2021 Three 1,2,4-triazole derivatives have been synthesised from hydrazides and 2-(2-hydroxyphenyl)-4H-1,3-benzoaxin-4-one. With the aid of Conceptual Density Functional Theory (CDFT), Molecular Electrostatic Potential (MEP) and Quantum Theory of Atoms in ...
Louis-Charl C. Coetzee +4 more
doaj +1 more source
Rapid Total Synthesis of DARPin pE59 and Barnase [PDF]
, 2013 We report the convergent total synthesis of two proteins: DARPin pE59 and Bacillus amyloliquefaciens RNase (Barnase). Leveraging our recently developed fast-flow peptide-synthesis platform, we rapidly explored numerous conditions for the assembly of long
Mong, Surin Khai +3 more
core +1 more source
Novel one-pot process for the synthesis of ethyl 2-imino-4-methyl-2,3-dihydrothiazole-5-carboxylates [PDF]
Journal of the Serbian Chemical Society, 2015 A facile one-pot two-step process for the synthesis of ethyl 2-imino-4-methyl-2,3-dihydrothiazole-5-carboxylates via the cyclocondensation of ethyl 2-thiocyanatoacetoacetate with a variety of hydrazine and hydrazide derivatives has been ...
Beyzaei Hamid, Aryan Reza, Moghadas Hadi
doaj +1 more source
Organic solvent-free synthesis of sulfonyl hydrazides in water
Tetrahedron Green Chem, 2023 An organic solvent-free synthesis of sulfonyl hydrazides has been achieved in water. The reactions of equimolar amount of sulfonyl chlorides and hydrazines afforded a series of substituted sulfonyl hydrazides at 60 °C for 1 h in water as a solvent in ...
Shizuki Noda, Shinji Tanimori
doaj +1 more source
A facile synthesis of N-Z/Boc-protected 1,3,4-oxadiazole-based peptidomimetics employing peptidyl thiosemicarbazides [PDF]
, 2010 Synthesis of 1,3,4-oxadiazole containing peptidomimetics is described by a p-TsCl/pyridine-mediated cyclization of the corresponding dipeptidyl thiosemicarbazides, which are readily prepared by coupling N-protected amino acid hydrazides with amino acid ...
Lamani, R.S. +2 more
core +1 more source
Synthesis and Antioxidant Activity of Some New Coumarinyl-1,3-Thiazolidine-4-ones
Molecules, 2010 A series of Schiff’s bases (E)-N-2-aryliden-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetohydrazides 2a-l and N-(2-(substituted phenyl)-4-oxo-thiazolidin-3-yl)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetamides 3a-l were synthesized and evaluated for their ...
Valentina Rajković +4 more
doaj +1 more source
Results in Chemistry, 2022 An efficient, fast, and environmentally gentle protocol for phthaloylation of amines, hydrazines and hydrazides via transamidation is described. The current research focuses on the phthaloylation of alicyclic, aliphatic, aromatic, heterocyclic amines ...
Prerna Ganwir +2 more
doaj +1 more source