Results 61 to 70 of about 18,659 (282)

Calcification of subcutaneously implanted collagens in relation to cytotoxicity, cellular interactions and crosslinking [PDF]

, 1995
In general, calcification of biomaterials occurs through an interaction of host and implanted material factors, but up to now the real origin of pathologic calcification is unknown.
Dijkstra, P.J., Feijen, J., Luyn, M.J.A. van, Olde Damink, L.H.H., Wachem, P.B. van   +4 more
core   +3 more sources

Recent Progress in the Use of Glucagon and Glucagon Receptor Antagonists in the Treatment of Diabetes Mellitus [PDF]

, 2014
Glucagon is an important pancreatic hormone, released into blood circulation by alpha cells of the islet of Langerhans. Glucagon induces gluconeogenesis and glycogenolysis in hepatocytes, leading to an increase in hepatic glucose production and ...
Ahn JM, Al-Shamsi M, Ali S, Baggio LL, Birnbaumer L, Brand CL, Brand CL, Brand CL, Brand CL, Burcelin R, Cascieri MA, Cho YM, Christensen DP, Conarello SL, Costa FF, Dallas-Yang Q, Dharanipragada R, Duffy JL, Ernest Adeghate, Evans-Molina C, Gelling RW, Gyorgy Szalai, Hamm CA, Hansen LH, Hruby VJ, Hruby VJ, Huba Kalasz, Jaipaul Singh, Jiang G, Johnson DG, Kawai K, Kim RM, Knappe TA, Kodra JT, Kurukulasuriya R, Ladouceur GH, Lau J, Lee Y, Liang R, Liang Y, Ling A, Ling A, Lister R, Lok S, Longuet C, McGarry JD, Merlen C, Mohamed Lotfy, Parker JC, Parker JC, Petersen KF, Pierce KL, Pinney SE, Pogribny IP, Ponery AS, Potterat O, Quesada I, Qureshi SA, Ray-Gallet D, Rivera N, Shah P, Shah P, Shen DM, Shen DM, Shiao LL, Sinz C, Sloop KW, Sorensen H, Soupart A, Unson CG, Van Tine BA, Wang Q, Xu E, Zhang BB   +73 more
core   +1 more source

Identification of 3-[(4-Acetylphenyl)(4-Phenylthiazol-2-Yl)Amino]Propanoic Acid Derivatives as Promising Scaffolds for the Development of Novel Anticancer Candidates Targeting SIRT2 and EGFR

Pharmaceuticals
Background: A series of novel polysubstituted thiazole derivatives were synthesized, and their antiproliferative properties were evaluated using both 2D and 3D lung cancer models.
Božena Golcienė, Povilas Kavaliauskas, Waldo Acevedo, Birutė Sapijanskaitė-Banevič, Birutė Grybaitė, Ramunė Grigalevičiūtė, Rūta Petraitienė, Vidmantas Petraitis, Vytautas Mickevičius   +8 more
doaj   +1 more source

Bivalent Enzyme Inhibitors Discovered Using Dynamic Covalent Chemistry [PDF]

, 2012
A bivalent dynamic covalent chemistry (DCC) system has been designed to selectively target members of the homodimeric glutathione-S-transferase (GST) enzyme family.
Ang, Appiah-Opong, Beeren, Beeren, Beeren, Bhat, Bhat, Blanden, Bunyapaiboonsri, Bunyapaiboonsri, Carroll, Cheng, Cho, Corbett, Corbett, Corbett, Cordes, Cousins, Deng, Dirksen, Dorion, Erlanson, Federici, Furlan, Gromova, Habig, Hayes, Hochgürtel, Huc, Jao, Li, Lins, Liu, Liénard, Liénard, Lyon, Maeda, Mahajan, Mannervik, McIlwain, Oakley, Oakley, Oakley, Patskovsky, Poulsen, Poulsen, Ralat, Ramström, Ramström, Roberts, Romieu, Ryoo, Sampsonas, Severin, Sheehan, Shi, Simpson, Simpson, Son, Townsend, Tsuboi, Woon, Xue, Zameo, Zameo   +64 more
core   +1 more source

Development of highly selective ligands for separations of actinides from lanthanides in the nuclear fuel cycle [PDF]

, 2011
This account summarizes recent work by us and others on the development of ligands for the separation of actinides from lanthanides contained in nuclear waste streams in the context of a future European strategy for nuclear waste management. The current
Harwood, Laurence, Hudson, Michael J., Lewis, Frank   +2 more
core   +1 more source

A new class of dihaloquinolones bearing N'-aldehydoglycosylhydrazides, mercapto-1,2,4-triazole, oxadiazoline and a-amino ester precursors: synthesis and antimicrobial activity

Journal of the Brazilian Chemical Society, 2003
Reaction of the quinolones 6-8 with hydrazine afforded the hydrazide 9-11 in moderate yields. Condensation of 9 and 11 with CS2 /KOH furnished the potassium salts 13 and 14, respectively, which spontaneously afforded the 3-(1,2,4-triazolyl)-quinolones 15
Al-Soud Yaseen A., Al-Masoudi Najim A.
doaj  

Oxidations of Benzhydrazide and Phenylacetic Hydrazide by Hexachloroiridate(IV): Reaction Mechanism and Structure–Reactivity Relationship

Molecules, 2020
Benz(o)hydrazide (BH) is the basic aryl hydrazide; aryl hydrazides have been pursued in the course of drug discovery. Oxidations of BH and phenylacetic hydrazide (PAH) by hexachloroiridate(IV) ([IrCl6]2−) were investigated by use of stopped-flow ...
Xiaolai Zhang
doaj   +1 more source

Biocompatibility and tissue regenerating capacity of crosslinked dermal sheep collagen [PDF]

, 1994
The biocompatibility and tissue regenerating capacity of four crosslinked dermal sheep collagens (DSC) was studied. In vitro, the four DSC versions were found to be noncytotoxic or very low in cytoxicity.
Anselme, Bannenberg, Berry, Bessis, Blaauw, Damink, Damink, Damink, Damink, Damink, Damink, Damink, Flory, Galli, Gorham, Levy, Nedkov, Petite, Schoen, Speer, Srivastava, Steinberg, van der Laan, van der Wal, van Gulik, van Luyn, van Luyn, van Luyn, van Luyn, van Luyn, van Wachem, van Wachem, van Wachem, van Wachem, Wasserman, Weiss, Werkmeister   +36 more
core   +2 more sources

Pemodelan Molekul Turunan p-Metoksi sinnamoil Hidrazida Sebagai Inhibitor Checkpoint Kinase 1 dan Inhibitor Aromatase secara In silico

Pharmaceutical Sciences and Research, 2017
The development of anticancer drugs from ethyl p-methoxycinnamate (EPMC) derivatives continues to obtain compounds that have high ability of cancer cells apoptosis and minimal side effects.
Galih Satrio Putra, Melanny Ika Sulistyowaty, Juni Ekowati   +2 more
doaj   +1 more source

Synthesis and Characterization of Oxomolybdenum and Oxovanadium Complexes [PDF]

, 2010
Synthesis and characterization of two different O-N donor hydrazide ligands and their corresponding dioxomolybdenum(VI) and oxovanadium(V) complexes have been reported.
Kar, P
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