Results 61 to 70 of about 2,940 (175)

Hydrazinolysis of lipids and analysis of their constituent fatty acids

Journal of Lipid Research, 1983
Treatment of O-acyl lipids with hydrazine degrades them to hydrazides of the constituent fatty acids. These hydrazides react with acetone to yield less polar and more volatile N'-isopropylidenealkanohydrazides, R-CO-NH-N = C(CH3)2, which strongly absorb ...
V P Agrawal
doaj   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

Smart molecular design for functional cellulose gels and flexible devices

Smart Molecules, EarlyView.
This review systematically outlines the performance enhancement of cellulose gels, presenting optimization strategies across molecular, supramolecular, and macroscopic scales. It discusses advanced approaches to improve their mechanical, electrical, and thermal properties, and highlights promising applications in flexible robotics, electric devices, e ...
Zeshi Li, Minxin Wang, Geyuan Jiang, Jianhong Zhou, Donghan Li, Weihua Zhang, Dawei Zhao   +6 more
wiley   +1 more source

New 4-(Morpholin-4-Yl)-3-Nitrobenzhydrazide Based Scaffold: Synthesis, Structural Insights, and Biological Evaluation

Molecules
The search for new antimicrobial agents is one of the major challenges in contemporary medicinal chemistry due to the global issue of increasing drug resistance.
Michał Janowski, Sara Janowska, Sylwia Andrzejczuk, Urszula Kosikowska, Radomir Jasiński, Barbara Mirosław, Marcin Feldo, Monika Wujec, Oleg M. Demchuk   +8 more
doaj   +1 more source

In Vitro Metabolism and Analytical Characterization of SLU‐PP‐332 and SLU‐PP‐915: Novel Pan‐ERR Agonists With Doping Potential

Rapid Communications in Mass Spectrometry, Volume 40, Issue 8, 30 April 2026.
ABSTRACT Rationale Estrogen‐related receptor (ERR) agonists such as the drug candidates SLU‐PP‐332 and SLU‐PP‐915 are currently being investigated as exercise mimetics, given their ability to trigger human physiological processes similar to those initiated by actual physical activity.
Tristan Möller, Oliver Krug, Mario Thevis   +2 more
wiley   +1 more source

Synthesis, structures and Hirshfeld surface analyses of 2-hydroxy-N′-methylacetohydrazide and 2-hydroxy-N-methylacetohydrazide

Acta Crystallographica Section E: Crystallographic Communications
The structures of the title compounds 2-hydroxy-N′-methylacetohydrazide, 1, and 2-hydroxy-N-methylacetohydrazide, 2, both C3H8N2O2, as regioisomers differ in the position of the methyl group relative to the N atoms in 2-hydroxy-acetohydrazide.
Oleksandr V. Vashchenko, Dmytro M. Khomenko, Viktoriya V. Dyakonenko, Rostyslav D. Lampeka   +3 more
doaj   +1 more source

Understanding Conformational Preferences of Atropisomeric Hydrazides and Its Influence on Excited State Transformations in Crystalline Media

Molecules, 2019
Hydrazides derivatives were evaluated to understand the role of N−N bond in dictating the outcome of photoreactions in the solid state.
Akila Iyer, Angel Ugrinov, J. Sivaguru
doaj   +1 more source

Synthesis and biological evaluation of new hydrazide-Schiff bases

Bangladesh Journal of Pharmacology, 2015
A new series of N-({5-(substituted aryl)-furan-2-yl}-methylidene)-hydrazides were synthesized with a new class of Schiff bases derived from the reaction of substituted phenyl-1-ketohydrazide 2 or 2-(4-chloro-3-methylaryloxy) acetohydrazide 3 with ...
Asif Husain, Munendra M. Varshney, Versha Parcha, Aftab Ahmad, Shah Alam Khan   +4 more
doaj   +1 more source

Synthesis of oleophilic electron-rich phenylhydrazines

Beilstein Journal of Organic Chemistry, 2012
Phenylhydrazines 1 substituted with two or three long-chain alkyl, alkoxy or alkylsulfanyl groups were successfully prepared by acid-induced removal of the Boc group in hydrazides 2.
Aleksandra Jankowiak, Piotr Kaszyński
doaj   +1 more source

Microwave-Assisted Synthesis and Biological Evaluation of Some Coumarin Hydrazides

Journal of the Turkish Chemical Society, Section A: Chemistry, 2018
In this work, 15 different coumarin hydrazides were successfully synthesized and screened for their antioxidant and antilipase activities. To do this, firstly, salicylaldehyde derivatives and 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum's Acid) were ...
Fatih Yılmaz, Özlem Faiz
doaj   +1 more source