Results 121 to 130 of about 59,471 (323)

Synthesis, Identification and Preliminary Pharmacological Evaluation of New Hydrazone and 1, 3, 4-oxadiazole Derivatives of Ketorolac

open access: yesIraqi Journal of Pharmaceutical Sciences
New series of hydrazones (3a–b) and 1, 3, 4-oxadiazole S-alkylated derivatives (5a–b) of ketorolac (NSAID) were synthesized and their structures were identified by using ATR-FT-IR and ¹HNMR spectroscopic analytical techniques.
Aliaa AL-Hashemmi, Muthanna S. Farhan
doaj   +1 more source

Novel Pt(ii) complexes with modified aroyl-hydrazone Schiff-base ligands: synthesis, cytotoxicity and action mechanism [PDF]

open access: bronze, 2019
Jungang Deng   +8 more
openalex   +1 more source

Kinetic and mechanistic studies of Pd-catalyzed amination of aryl halides

open access: yes, 2009
The Pd-catalyzed amination of aryl halides (Buchwald-Hartwig amination) has become a versatile and widely used technology to synthesize and produce aromatic amines relevant in pharmaceutical and agrochemical industries.
Ferretti, Antonio, Ferretti, Antonio
core   +1 more source

In Vitro Antibacterial Activities and Calf Thymus DNA–Bovine Serum Albumin Interactions of Tridentate NNO Hydrazone Schiff Base–Metal Complexes

open access: yesInorganics
Their demonstrable bioactive characteristics, coupled with their wide structural diversity and coordination versatility, render Schiff bases and their coordination complexes biologically active compounds demonstrating outstanding properties.
Maida Katherine Triviño-Rojas   +4 more
doaj   +1 more source

Alkynyltriazenes in Photochemical Metal‐Free Doyle–Kirmse Rearrangements

open access: yesAngewandte Chemie International Edition, EarlyView.
A metal‐ and additive‐free photocatalytic Doyle–Kirmse reaction of alkynyl triazenes is described, proceeding via cyanocarbene intermediates. This strategy enables the efficient construction of highly substituted asymmetric carbon centers with broad substrate scope, delivering synthetically valuable nitriles.
Ningning Liu   +7 more
wiley   +1 more source

Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies

open access: yesMolecules
A new class of benzimidazole-based derivatives (4a–j, 5, and 6) with potential dual inhibition of EGFR and BRAFV600E has been developed. The newly synthesized compounds were submitted for testing for antiproliferative activity against the NCI-60 cell ...
Bahaa G. M. Youssif   +6 more
doaj   +1 more source

Bioenergetics Consequences of Mitochondrial Transplantation in Cardiomyocytes. [PDF]

open access: yes, 2020
Background Mitochondrial transplantation has been recently explored for treatment of very ill cardiac patients. However, little is known about the intracellular consequences of mitochondrial transplantation.
Ali Pour, Paria   +2 more
core  

hydrazide hydrazones

open access: yes, 2019
Citation: 'hydrazide hydrazones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02877 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

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