Results 251 to 260 of about 59,471 (323)

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 203-237, January 2026.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller   +5 more
wiley   +1 more source

Substrate recognition mechanisms of ʟ‐glutamate oxidase from Streptomyces sp. and its conversion to ʟ‐tyrosine oxidase

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract ʟ‐Amino acid oxidase (LAAO) is a flavoenzyme that catalyzes the oxidative deamination of ʟ‐amino acids, producing α‐keto acids, ammonia, and hydrogen peroxide. Among LAAOs, ʟ‐glutamate oxidase (LGOX) from Streptomyces sp. X‐119‐6 exhibits exceptionally high substrate specificity for ʟ‐glutamate. LGOX is expressed as a homodimeric precursor and
Yuka Ueda   +5 more
wiley   +1 more source

A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy [PDF]

open access: yes, 2018
Allavena, Giulia   +5 more
core   +1 more source

Eugenol‐Based Thiazole Derivatives Inhibit the MepA Efflux Pump in Staphylcoccus aureus

open access: yesChemistrySelect, Volume 11, Issue 3, 22 January 2026.
ABSTRACT Multidrug resistant (MDR) bacteria are considered critical priority pathogens by the World Health Organization (WHO). Considering the relevance of antibacterial drug development in this scenario, the present research study aimed to evaluate the antibacterial activity of eugenol‐based thiazole derivatives and analyze their potential to inhibit ...
Ray Silva de Almeida   +13 more
wiley   +1 more source

Rotaxanes with integrated photoswitches: design principles, functional behavior, and emerging applications. [PDF]

open access: yesBeilstein J Org Chem
Matsushima JE   +4 more
europepmc   +1 more source

Emerging Biomedical Engineering Therapies for Infected Diabetic Foot Ulcers: Toward Antibacterial Functionalization and Pathology‐Responsive Regulation

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao   +8 more
wiley   +1 more source

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