ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller +5 more
wiley +1 more source
Hydrogen-bonded supramolecular polymer networks for effective removal of perchlorate in water via clustered hydrogen-bonding. [PDF]
Tian J +9 more
europepmc +1 more source
Abstract ʟ‐Amino acid oxidase (LAAO) is a flavoenzyme that catalyzes the oxidative deamination of ʟ‐amino acids, producing α‐keto acids, ammonia, and hydrogen peroxide. Among LAAOs, ʟ‐glutamate oxidase (LGOX) from Streptomyces sp. X‐119‐6 exhibits exceptionally high substrate specificity for ʟ‐glutamate. LGOX is expressed as a homodimeric precursor and
Yuka Ueda +5 more
wiley +1 more source
Development of the 5‑Nitrosalicaldehyde Arylhydrazones as Anticancer (MCF‑7 and HCT116) Agents Targeting Inhibition of VEGFR‑2 and Cytokines (IL‑6 and TNF-α). [PDF]
Nkoana JK +3 more
europepmc +1 more source
A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy [PDF]
Allavena, Giulia +5 more
core +1 more source
Eugenol‐Based Thiazole Derivatives Inhibit the MepA Efflux Pump in Staphylcoccus aureus
ABSTRACT Multidrug resistant (MDR) bacteria are considered critical priority pathogens by the World Health Organization (WHO). Considering the relevance of antibacterial drug development in this scenario, the present research study aimed to evaluate the antibacterial activity of eugenol‐based thiazole derivatives and analyze their potential to inhibit ...
Ray Silva de Almeida +13 more
wiley +1 more source
Rotaxanes with integrated photoswitches: design principles, functional behavior, and emerging applications. [PDF]
Matsushima JE +4 more
europepmc +1 more source
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao +8 more
wiley +1 more source
Innovative Azo Disperse Dyes Containing a Hydrazide-Hydrazone Moiety: Design, DFT Calculations, Antimicrobial and Antibiofilm Activities, and Dyeing Performance on Polyester Fabrics. [PDF]
Elgammal WE +9 more
europepmc +1 more source

