Results 21 to 30 of about 10,394 (273)

Base-Mediated Generation of Ketenimines from Ynamides: Addition of Hydrazones to Give Acetimidohydrazides [PDF]

open access: yes, 2021
Under basic conditions, N-arylketenimines were generated in situ from N-Boc ynamides and reacted with hydrazones. Under heating, an addition of the hydrazone onto the central carbon of the ketenimine takes place, giving rise to various ...
Kevin, Cariou   +2 more
core   +1 more source

Synthesis and antibacterial evaluation of novel hydrazones and bis-hydrazones containing 1,2,3-triazole moiety

open access: yesJournal of Taibah University for Science, 2022
The current work reports the synthesis of novel hydrazones and bis-hydrazones containing 1,2,3-triazole moiety. Base-assisted aldol condensation of 4-acetyl-1,2,3-triazole 1a (R = NO2) and anisaldehyde (2) gave the corresponding chalcone 3 in 88% yield ...
Mohammed A. Baashen
doaj   +1 more source

New possibilities of the functionalization of 6-hydrazino-1,3-dimethyluracils: one-pot synthesis of 5,7-dimethylpyrazolopyrimidine-4,6-dione and 1,3-dimethyl-5-arylidenebarbituric acid derivatives

open access: yesChimica Techno Acta, 2021
3-aryl-5,7-dimethylpyrazolopyrimidine-4,6-diones and 5-benzylidene-1,3-dimethylpyrimidine-2,4,6-triones were obtained by heating hydrazones of 1,3-dimethyl-6 -hydrazinouraciles in trifluoroacetic acid (TFA).
Yu. A. Azev   +2 more
doaj   +1 more source

Attempts to Access a Series of Pyrazoles Lead to New Hydrazones with Antifungal Potential against Candida species including Azole-Resistant Strains

open access: yesMolecules, 2021
The treatment of benzylidenemalononitriles with phenylhydrazines in refluxing ethanol did not provide pyrazole derivatives, but instead furnished hydrazones. The structure of hydrazones was secured by X-ray analysis.
Georgiana Negru   +6 more
doaj   +1 more source

2,4-Dinitrobenzaldehyde hydrazone [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2008
The title compound, C(7)H(6)N(4)O(4), plays an important role in the synthesis of biologically active compounds. The planar hydrazone group is oriented at a dihedral angle of 8.27 (3)° with respect to the benzene ring. In the crystal structure, inter-molecular N-H⋯O and N-H⋯N hydrogen bonds link the mol-ecules.
Zhang, N.   +4 more
openaire   +3 more sources

Terpenoid Hydrazones as Biomembrane Penetration Enhancers: FT-IR Spectroscopy and Fluorescence Probe Studies

open access: yesMolecules, 2021
Hydrazones based on mono- and bicyclic terpenoids (verbenone, menthone and carvone) have been investigated in vitro as potential biomembrane penetration enhancers.
Mariia Nesterkina   +3 more
doaj   +1 more source

Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones [PDF]

open access: yes, 2013
2-Substituted oxetan-3-ones can be prepared in good yields and enantioselectivities (up to 84% ee) by the metalation of the SAMP/RAMP hydrazones of oxetan-3-one, followed by reaction with a range of electrophiles that include alkyl, allyl, and benzyl ...
Geden, Joanna V.   +3 more
core   +1 more source

Synthesis, Characterization and Antibacterial Activity Evaluation of New Indole-Based Derivatives

open access: yesIraqi Journal of Pharmaceutical Sciences, 2020
A new series of N-acyl hydrazones (4a-g) derived from indole-3-propionic acid (IPA) were synthesized. These N-acyl hydrazones were prepared by the reaction of 3-(1H-indol-3-yl) propane hydrazide and aldehyde in the existence of glacial acetic acid as a ...
Ahmed T. Sulaiman, Susan W. Sarsam
doaj   +1 more source

Design, Synthesis, and Anticancer Evaluation of Novel Tetracaine Hydrazide-Hydrazones [PDF]

open access: yes, 2023
Tetracaine is an ester derivative used as a local anesthetic molecule. In this study, a series of novel Tetracaine derivatives bearing hydrazide-hydrazone moiety were designed, synthesized, and evaluated for anticancer activity.
Nalan İmamoğlu (14690862)   +1 more
core   +1 more source

Synthesis of Some Substituted 1,3,4-Oxadiazoles from Hydrazones [PDF]

open access: yesمجلة التربية والعلم, 2009
In this paper the synthesis of some 2-(3-pyridyl)-5-aryl-1,3,4-oxadiazoles from hydrazones is reported. Nicotinic acid was converted to ethyl nicotinate (1) by its reaction with thionyl chloride and the resultant acid chloride was treated with absolute ...
Khalid Daoud, A. Ahmad, Amal Ali
doaj   +1 more source

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