Results 21 to 30 of about 10,379 (265)

Base-Mediated Generation of Ketenimines from Ynamides: Addition of Hydrazones to Give Acetimidohydrazides

, 2021
Under basic conditions, N-arylketenimines were generated in situ from N-Boc ynamides and reacted with hydrazones. Under heating, an addition of the hydrazone onto the central carbon of the ketenimine takes place, giving rise to various ...
Kevin, Cariou, Agathe C. A., D’Hollander, Capucine, Mahe   +2 more
core   +1 more source

Computational Studies of Some Hydrazone Derivatives as Antibacterial Agent: DFT and Docking Methods [PDF]

Journal of Pure and Applied Chemistry Research, 2019
Quantum chemical calculations through density functional theory and docking study were carried out on a set of seven hydrazones and S. aureus cell line (4b19) so as to observe their inhibitory abilities of hydrazones.
Abel Oyebamiji, B. Benjamin Adeleke, Ajibade Adejoro, Oyedeji Folashade   +3 more
doaj   +1 more source

Synthesis, E/Z isomerisation and antimicrobial studies of different structured novel ketone derivatives

Journal of the Turkish Chemical Society, Section A: Chemistry, 2019
In this study five different structured mono ketones’ (k1- k5) novel derivatives as five new hydrazones (h1-h5) and five new semicarbazones (s1-s5) were synthesized.
Aysema SAYIK MEHAN, Ebru SENTURK, Emel MATARACI KARA, Ayse Serguzel YUSUFOGLU   +3 more
doaj   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Synthesis, Characterization, Single-Crystal X-ray Structure and Biological Activities of [(Z)-N′-(4-Methoxybenzylidene)benzohydrazide–Nickel(II)] Complex

Crystals, 2021
(Z)-N′-(4-methoxybenzylidene)benzohydrazide (HL) and its Ni(II) complex (Ni(II)-2L) were synthesized using eco-friendly protocols. The single X-ray crystal structure of Ni(II)-2L was solved.
Inas Al-Qadsy, Abdel-Basit Al-Odayni, Waseem Sharaf Saeed, Ali Alrabie, Arwa Al-Adhreai, Lena Ahmed Saleh Al-Faqeeh, Prem Lama, Abdulaziz Ali Alghamdi, Mazahar Farooqui   +8 more
doaj   +1 more source

Synthesis and Conformational Assignment of N-(E)-Stilbenyloxymethylenecarbonyl-Substituted Hydrazones of Acetone and o-(m- and p-) Chloro- (nitro-) benzaldehydes by Means of and NMR Spectroscopy

Journal of Spectroscopy, 2013
Eighteen new N-(E)-stilbenyloxyalkylcarbonyl-substituted hydrazones of ortho- (meta- and para-) chloro- (nitro-) benzaldehydes 1–18 and two analogous hydrazones of acetone 19-20 were prepared.
Przemysław Patorski, Elżbieta Wyrzykiewicz, Grażyna Bartkowiak   +2 more
doaj   +1 more source

Selective Nitrate Transmembrane Transport Through Adaptive Weak C─H Bonding Cyanostilbene Water Channels

Angewandte Chemie, EarlyView.
Here we demonstrate that weak HB CH donor cyanostilbenes promote water/ion transport through their ability to form less‐ordered transient water channels within the lipid bilayer with increased water permeability and NO3−/ Cl− selectivity. ABSTRACT Transmembrane water transport strongly depends on how dynamic, translocating water clusters are stabilized
Ioan Stroia, Dan‐Dan Su, Yuhao Li, Niculina Hadade, Ion Grosu, Arie van der Lee, Mihail Barboiu   +6 more
wiley   +2 more sources

Design, Synthesis, and Anticancer Evaluation of Novel Tetracaine Hydrazide-Hydrazones

, 2023
Tetracaine is an ester derivative used as a local anesthetic molecule. In this study, a series of novel Tetracaine derivatives bearing hydrazide-hydrazone moiety were designed, synthesized, and evaluated for anticancer activity.
Nalan İmamoğlu (14690862), M. İhsan Han (14690859)   +1 more
core   +1 more source

Visible-light mediated directed perfluoroalkylation of hydrazones

, 2017
A convenient and efficient protocol was reported to access a series of perfluoroalkylated aromatic aldehyde hydrazones. Aliphatic aldehyde hydrazones and N-monosubstituted hydrazones which are unreactive in previously reported hydrazone ...
Hui-qiong Ni, Zi-wei Xi, Jian-jun Shi, Peng Zhi, Yong-miao Shen, Wei Wang, Heng Ji   +6 more
core   +1 more source

Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy

Angewandte Chemie, EarlyView.
We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu, Yura Lee, Sanghee Yoon, Yun Wang, Yejin Cho, Seongyu Choi, Lu Lu, Hua Zhang, Sun Choi, Ki Taek Nam, Juyoung Yoon   +10 more
wiley   +2 more sources