Results 61 to 70 of about 126,036 (251)

Fused Imidazopyrazoles: Synthetic Strategies and Medicinal Applications

Journal of Chemistry, Volume 2014, Issue 1, 2014., 2014
The current review summarizes the known synthetic routes of fused imidazopyrazoles. This review is classified into two main categories based on the type of annulations, for example, annulation of the imidazole ring onto a pyrazole scaffold or annulation of the pyrazole ring onto an imidazole scaffold. Some medicinal applications of imidazopyrazoles are
Rizk E. Khidre, Bakr F. Abdel-Wahab, Othman Y. Alothman, Liviu Mitu   +3 more
wiley   +1 more source

Synthesis and tautomerism of aryl- and hetaryl-azo derivatives of bi- and tri-heterocycles

Journal of Advanced Research, 2010
This review summarizes results from the literature concerning synthesis and azo-hydrazone tautomerism of arylazo- and hetarylazo-derivatives of various bi- and tri-heterocycles reported by us and other research groups from 1981 to mid 2009.
Ahmad S. Shawali
doaj   +1 more source

Benzo[1,5]thiazepine: Synthesis, Reactions, Spectroscopy, and Applications

Organic Chemistry International, Volume 2013, Issue 1, 2013., 2013
This review article deals with synthesis and reactions of benzo[1,5]thiazepines and the related derivatives and their applications, biological activity as well as spectroscopic data. Most of the reported data on the methods of synthesis, chemical reactions, and biological activity of these heterocycles published over the last ten years are reviewed in ...
Khairy A. M. El-Bayouki, William Setzer
wiley   +1 more source

C-Glycosyl 1,2,4-triazoles: Synthesis of the 3-β-d-glucopyranosyl-1,5-disubstituted and 5-β-d-glucopyranosyl-1,3-disubstituted variants [PDF]

, 2018
K
Páhi, András, Somsák, László, Szabó, Erzsébet Katalin   +2 more
core   +1 more source

Synthetic Methods, Chemistry, and the Anticonvulsant Activity of Thiadiazoles

International Journal of Medicinal Chemistry, Volume 2013, Issue 1, 2013., 2013
The chemistry of heterocyclic compounds has been an interesting field of study for a long time. Heterocyclic nucleus 1,3,4‐thiadiazole constitutes an important class of compounds for new drug development. The synthesis of novel thiadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent ...
Bhawna Sharma, Amita Verma, Sunil Prajapati, Upendra Kumar Sharma, Hussein El-Subbagh   +4 more
wiley   +1 more source

Regioselective synthesis of some functionalized 3,4’-bis-(pyrazolyl)ketones and chemoselectivity in their reaction with hydrazine hydrate

, 2013
A new enamino ester, (E)-ethyl 3-(dipropylamino)acrylate, was prepared and used for synthesis of various pyrazole derivatives, 4a-k and 5a-d. Other new enaminone, (E)-ethyl 3-(3-(dimethylamino)acryloyl)-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate (8 ...
Hassaneen, Hamdi Mahmoud, Shawali, Ahmad Sami   +1 more
core   +1 more source

Novel Antimicrobial Agents: Fluorinated 2‐(3‐(Benzofuran‐2‐yl) pyrazol‐1‐yl)thiazoles

International Journal of Medicinal Chemistry, Volume 2013, Issue 1, 2013., 2013
A new series of 2‐pyrazolin‐1‐ylthiazoles 8a–d and 13–16 was synthesized by cyclization of N‐thiocarboxamide‐2‐pyrazoline with different haloketones and 2,3‐dichloroquinoxaline. The structures of the new compounds were confirmed by elemental analyses as well as NMR, IR, and mass spectral data.
Hanan A. Mohamed, Ehab Abdel-Latif, Bakr F. Abdel-Wahab, Ghada E. A. Awad, Armando Rossello   +4 more
wiley   +1 more source

1,3,4-Thiadiazoles of pharmacological interest: Recent trends in their synthesis via tandem 1,3-dipolar cycloaddition: Review

Journal of Advanced Research, 2014
This review article presents a survey of the utility of a new synthetic strategy for 1,3,4-thiadiazole derivatives based on reactions of nitrilimines with various functionalized sulfur dipolarophiles which proceed via tandem in situ 1,3-dipolar ...
Ahmad S. Shawali
doaj   +1 more source

Synthesis of new derivatives of the 1H-1,2,3-triazole ring using 1-aryl-5-phenyl-1H-1,2,3-triazole-4-carbohydrazides as precursors [PDF]

, 2023
Condensation of 1-(4-nitrophenyl)-5-phenyl-1H-1,2,3-triazole-4-carbohydrazide and phenyl isothiocyanate in ethanol in the presence of a catalytic quantity of triethylamine under reflux gave 5-(1-(4-nitrophenyl)-5-phenyl-1H-1,2,3-triazol-4-yl)-N-phenyl-1 ...
Abdel-Wahab, Bakr F., Bekheit, Mohamed S., El-Hiti, Gamal A., Kariuki, Benson M., Mohamed, Hanan A.   +4 more
core   +1 more source

Synthesis and Antimicrobial Activity of Some New 1,3,4-Thiadiazole Derivatives

Molecules, 2012
New series of 1,3,4-thiadiazoles have been prepared via reaction of 1,3,4-thiadiazolenaminones 1 with N-phenyl 2-oxopropanehydrazonoyl chloride (2) in dioxane in the presence of triethylamine.
Mohamed R. Abdel Aziz, Magda A. Abdallah, Thoraya A. Farghaly   +2 more
doaj   +1 more source