Results 91 to 100 of about 113,315 (298)

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

Advanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang, Zhinang Yin, Yanqiong Shen, Gang Feng, Fangfang Dai, Dongyong Yang, Zhimin Deng, Jing Yang, Ruizhi Chen, Leifeng Yang, Xian Chen, Qing Sun, Chunyu Huang, Yanxiang Cheng, Hongbing Deng, Lianghui Diao, Longfei Li, Tailang Yin   +17 more
wiley   +1 more source

Nanopartículas de poli-ε-caprolactona carregadas com hidrocortisona: preparação usando planejamento fatorial e sua avaliação

Orbital: The Electronic Journal of Chemistry, 2012
Polymeric-nanoparticle systems such as nanocapsules and nanospheres have a great potential in applications for nanoencapsulation of corticosteroids which show low solubility in water.
Nayara Alonso Cazo, Edenir Rodrigues Pereira-Filho, Maria Fátima das Graças Fernandes da Silva, João Batista Fernandes, Paulo Cezar Vieira, Ana Cristina Puhl, Igor Polikarpov, Moacir Rossi Forim   +7 more
doaj   +1 more source

From Lab to Life: Self‐Powered Sweat Sensors and Their Future in Personal Health Monitoring

Advanced Science, EarlyView.
This review focuses on recent advances in self‐powered sweat sensors in personal health monitoring, including sweat sensors, energy harvesters, energy management, and their applications. It analyzes the difficulties and challenges in the research field of self‐powered sweat sensors and looks into the future direction of self‐powered sweat sensors from ...
Nan Gao, Guodong Xu, Gang Chang, Yuxiang Wu   +3 more
wiley   +1 more source

Quality of compounded hydrocortisone capsules used in the treatment of children.

European Journal of Endocrinology, 2017
OBJECTIVES Due to the lack of paediatric-licensed formulations, children are often treated with individualized pharmacy-compounded adult medication. An international web-based survey about the types of medication in children with adrenal insufficiency ...
U. Neumann, Daniela Burau, S. Spielmann, M. Whitaker, R. Ross, C. Kloft, O. Blankenstein   +6 more
semanticscholar   +1 more source

Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics

Advanced Science, EarlyView.
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch, Brittany Scheid, Kathryn A Davis, Brian Litt, Arian Ashourvan   +4 more
wiley   +1 more source

Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model

Scientific Reports, 2017
Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in
Sangwoo Ham, Yun-il Lee, Minkyung Jo, Hyojung Kim, Hojin Kang, Areum Jo, G. Lee, Y. Mo, S. Park, Yunjong Lee, Joo-Ho Shin, Yunjong Lee   +11 more
semanticscholar   +1 more source

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang, Guangmin Zheng, Xiaoyong Hu, Feng Tian, Tuo Li, Zheng Zhang, Kan Gong, Shiwei Chen, Lin Yuan, Yu Qi, Lin Li, Daofu Cheng, Liu Liu, Fuqiang Liu, Yujing Sun, Xiangdong Fang, Ruxing Zhao, Bing Liu, Chao Zhang   +18 more
wiley   +1 more source

The Effect of Intravenous Hydrocortisone (1 or 2 mg/kg) on Postoperative Shivering in Cesarean Section with Spinal Anesthesia

مجله دانشکده پزشکی اصفهان, 2017
Background: Postoperative shivering is one of the most prevalent complications that several methods were used for controlling it. This study aimed to determine the effect of two doses of intravenous hydrocortisone (1 or 2 mg/kg) on postoperative ...
Azim Honarmand, Mohammadreza Reza Safavi, Anahita Hirmanpour, Soheila Afzali   +3 more
doaj  

A Doubly Robust Instrumental Variable Approach for Estimating Average Treatment Effects in Time-to-Event Data with Unmeasured Confounding: Application to Real-World Data on ICU Patients with Septic Shock [PDF]

arXiv
Motivated by conflicting conclusions regarding hydrocortisone's treatment effect on ICU patients with vasopressor-dependent septic shock, we developed a novel instrumental variable (IV) estimator to assess the average treatment effect (ATE) in time-to-event data.
arxiv  

EFFECTS OF CORTICOSTERONE, HYDROCORTISONE, AND CORTICOTROPIN ON PRODUCTION OF ANTIBODIES IN RABBITS [PDF]

, 1955
Edward H. Kass, M. I. Kendrick, Maxwell Finland   +2 more
openalex   +1 more source