Results 11 to 20 of about 175,705 (335)

Prednisolone has the same cardiovascular risk profile as hydrocortisone in glucocorticoid replacement

Endocrine Connections, 2017
Introduction: Patients who need glucocorticoid replacement in both primary and secondary adrenal insufficiency (AI) have the choice of either once-daily prednisolone or thrice-daily hydrocortisone.
David J F Smith, Hemanth Prabhudev, Sirazum Choudhury, Karim Meeran   +3 more
doaj   +2 more sources

Development of Chitosan/Gelatin/Keratin Composite Containing Hydrocortisone Sodium Succinate as a Buccal Mucoadhesive Patch to Treat Desquamative Gingivitis [PDF]

Drug Development and Industrial Pharmacy, 2018
The aim of this research was to develop chitosan/gelatin/keratin composite containing hydrocortisone sodium succinate as a buccal mucoadhesive patch to treat desquamative gingivitis, which was fabricated through an environmental friendly process ...
Davoudi, Zahra, Eslahi, Niloofar, Houshmand, Behzad, Khoshroo, Kimia, Rabiee, Mohammad, Rasoulianboroujeni, Morteza, Tahriri, Mohammadreza, Tayebi, Lobat   +7 more
core   +3 more sources

Prevention of adrenal crisis: cortisol responses to major stress compared to stress dose hydrocortisone delivery in adrenal insufficiency [PDF]

medRxiv, 2020
Context: Patients with adrenal insufficiency require increased hydrocortisone cover during major stress to avoid life-threatening adrenal crisis. However, current treatment recommendations are not evidence-based.
Alessandro Prete, Angela E. Taylor, Irina Bancos, David J. Smith, Mark Foster, Sibylle Köhler, Violet Fazal-Sanderson, John Komninos, Donna O’Neil, Dimitra A. Vassiliadi, Christopher J Mowatt, Radu Mihai, Joanne L. Fallowfield, Djillali Annane, Janet M. Lord, Brian Keevil, John Wass, Niki Karavitaki, Wiebke Arlt   +18 more
openalex   +2 more sources

Systemic Hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants (the SToP-BPD study): Statistical analysis plan [PDF]

Trials, 2018
Background: Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth with short-term and long-term adverse consequences. Although the glucocorticoid dexamethasone has been proven to be beneficial for the prevention of BPD, there ...
Blom, H. (Henry), Cools, F. (Filip), Debeer, A. (Anne), Dijk, P.H. (Peter), Heijst, A.F.J. (Arno) van, Holman, R. (Rebecca), Jansen-Van Der Weide, M.C. (Marijke), Kaam, A.H. (Anton) van, Keymeulen, A. (Annelies), Kramer, B.W. (Boris), Kroon, A.A. (André), Marechal, Y. (Yoann), Merkus, M.P., Mohns, T. (Thilo), Nuytemans, K., Onland, W. (Wes), Plaskie, K. (Katleen), Rademaker, K.J. (K.), Rigo, V. (Vincent), Sijmons, M. (Marit), Te Pas, A.B. (Arjan B.), Theyskens, C. (Claire), van Straaten, H.L. (Henriette L.), Zonnenberg, I. (Inge)   +23 more
core   +3 more sources

Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model

Scientific Reports, 2017
Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in
Sangwoo Ham, Yun-Il Lee, Minkyung Jo, Hyojung Kim, Hojin Kang, Areum Jo, Gum Hwa Lee, Yun Jeong Mo, Sang Chul Park, Yun Song Lee, Joo-Ho Shin, Yunjong Lee   +11 more
doaj   +2 more sources

Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Sepsis is a common syndrome with substantial morbidity and mortality. A combination of vitamin C, thiamine, and corticosteroids has been proposed as a potential treatment for patients with sepsis. Objective To determine whether a combination
J. Sevransky, R. Rothman, D. Hager, G. Bernard, Samuel M. Brown, T. Buchman, L. Busse, C. Coopersmith, C. DeWilde, E. W. Ely, L. Eyzaguirre, A. Fowler, D. Gaieski, M. Gong, A. Hall, J. Hinson, M. Hooper, G. Kelen, Akram Khan, M. Levine, R. Lewis, C. Lindsell, Jessica S Marlin, A. McGlothlin, Brooks L. Moore, K. Nugent, S. Nwosu, C. Polito, T. Rice, E. Ricketts, C. Rudolph, Fred Sanfilippo, K. Viele, G. Martin, D. Wright   +34 more
semanticscholar   +1 more source

Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia.

New England Journal of Medicine, 2022
BACKGROUND Bronchopulmonary dysplasia is a prevalent complication after extremely preterm birth. Inflammation with mechanical ventilation may contribute to its development.

semanticscholar   +1 more source

Modified-Release Hydrocortisone in Congenital Adrenal Hyperplasia

Journal of Clinical Endocrinology and Metabolism, 2021
Context Standard glucocorticoid therapy in congenital adrenal hyperplasia (CAH) regularly fails to control androgen excess, causing glucocorticoid overexposure and poor health outcomes.
Merke Dp, M. A, A. W, B. a, Linden Hirschberg A, Juul A, N. J., Perry Cg, Prete A, Rees Da, Reisch N, Stikkelbroeck N, Touraine P, Maltby K, T. Fp, P. J, Rosser Rj   +16 more
semanticscholar   +1 more source

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants An ongoing
D. Angus, L. Derde, Farah Al-Beidh, D. Annane, Y. Arabi, A. Beane, Wilma van Bentum-Puijk, L. Berry, Zahra Bhimani, M. Bonten, C. Bradbury, F. Brunkhorst, M. Buxton, Adrian Buzgau, A. Cheng, M. D. de Jong, M. Detry, L. Estcourt, M. Fitzgerald, H. Goossens, Cameron Green, R. Haniffa, A. Higgins, Christopher M. Horvat, Sebastiaan J. Hullegie, P. Kruger, F. Lamontagne, P. Lawler, K. Linstrum, E. Litton, E. Lorenzi, J. Marshall, D. McAuley, Anna McGlothin, S. McGuinness, B. McVerry, S. Montgomery, P. Mouncey, S. Murthy, A. Nichol, R. Parke, Jane C. Parker, K. Rowan, A. Sanil, Marlene S. Santos, Christina T. Saunders, Christopher Seymour, Anne M Turner, F. L. van de Veerdonk, B. Venkatesh, R. Zarychanski, S. Berry, R. Lewis, C. McArthur, S. Webb, A. Gordon   +55 more
semanticscholar   +1 more source

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance It is unclear whether vitamin C, hydrocortisone, and thiamine are more effective than hydrocortisone alone in expediting resolution of septic shock.
T. Fujii, N. Luethi, P. Young, D. Frei, G. Eastwood, C. French, A. Deane, Y. Shehabi, L. Hajjar, G. Oliveira, A. Udy, N. Orford, S. Edney, A. Hunt, H. Judd, L. Bitker, L. Cioccari, T. Naorungroj, Fumitaka Yanase, S. Bates, F. McGain, Elizabeth P Hudson, W. Al-Bassam, D. B. Dwivedi, C. Peppin, P. Mccracken, J. Orosz, M. Bailey, R. Bellomo   +28 more
semanticscholar   +1 more source