Results 11 to 20 of about 96,281 (281)

Comparative Effectiveness of Less vs. More Frequent Hydrocortisone Dosing in Septic Shock [PDF]

Critical Care Explorations
OBJECTIVES:. Guidelines recommend hydrocortisone as an adjunctive treatment in septic shock, but the optimal dosing regimen is unknown. A national shortage of hydrocortisone in 2023 prompted a change in institutional practice for hydrocortisone ...
Alan Hao, PharmD, Tianshi David Wu, MD, MHS, Keegan Collins, PA-C, Danielle Guffey, MS, Rebecca Kessinger, PharmD, Meghna Vallabh, PharmD, Ali Omranian, MD   +6 more
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Long-term administration of hydrocortisone: down-regulating the level of cytokine and resulting in injuring testicular tissue of juvenile mice [PDF]

BMC Pharmacology and Toxicology
Background As an important glucocorticosteroid hydrocortisone has been widely used in clinical practice. Even though a series of side effects induced by long-term administration of hydrocortisone are known, but side effects related to testicular injury ...
Xiaoyi Zhang, Junhua Zhou, Yifan Yang, Yaonan Wang, Shurui Zhao, Jianhui Wu, Ming Zhao, Shiqi Peng   +7 more
doaj   +2 more sources

Evaluation of Hydrocortisone Discontinuation Strategies in Septic Shock: A Retrospective Cohort Study [PDF]

Critical Care Explorations
IMPORTANCE:. While corticosteroid administration in septic shock has been shown to reduce vasopressor requirements and accelerate shock reversal, the optimal discontinuation strategy remains unexplored. OBJECTIVES:.
Hanine O. AlMubayedh, PharmD, BCPS, BCCCP, Rayd A. AlMehizia, PharmD, BCCCP, Abdul Salam, PhD, Razan M. AlGhunaim, PharmD, BCCCP, Othman Mohammed, MD, Abdullah A. Alrbiaan, MD, Nada S. AlQadheeb, PharmD, BCCCP, FCCP, FCCM   +6 more
doaj   +2 more sources

In-use Stability of Hydrocortisone Injection Preparations at a Regional Referral Hospital in Central Java

Jurnal Ilmiah Medicamento
Hydrocortisone Sodium Succinate 50mg injection is widely used in perinatology wards. These wards cater to newborns (0-28 days), low birth weight (
Erza Genatrika, Elza Sundhani, Adriana Eka Fitri   +2 more
doaj   +3 more sources

Cutaneous Permeation of a Percutaneously Applied Glucocorticoid Using Plant-Based Anionic Phospholipids in Hydrogenated Vegetable Oil: A Preliminary Study

Medicina, 2022
Purpose: It is important that, when corticosteroids are used therapeutically, concentrations be reduced as much as possible to mitigate potential adverse events and side effects.
Jack V. Greiner, Hridaya N. Bhargava, Thomas Glonek, Donald R. Korb, Michael E. Lindsay, Paula J. Oliver   +5 more
doaj   +1 more source

Penetapan Kadar Hidrokortison Asetat dalam Sediaan Krim Mengandung Pengawet Nipagin secara Spektrofotometri Derivatif Orde Pertama

Pharmaceutical Sciences and Research, 2014
The simple and rapid spectrophotometric methods were developed for analysis of hydrocortisone acetate in cream pharmaceutical formulations containing nipagin as preservative.
Hayun, Nelly Dhevita Leswara, Luthfi Zarkasih   +2 more
doaj   +1 more source

Prednisolone has the same cardiovascular risk profile as hydrocortisone in glucocorticoid replacement

Endocrine Connections, 2017
Introduction: Patients who need glucocorticoid replacement in both primary and secondary adrenal insufficiency (AI) have the choice of either once-daily prednisolone or thrice-daily hydrocortisone.
David J F Smith, Hemanth Prabhudev, Sirazum Choudhury, Karim Meeran   +3 more
doaj   +1 more source

Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participant data

BMJ Open, 2020
Introduction The benefits and risks of low-dose hydrocortisone in patients with septic shock have been investigated in numerous randomised controlled trials and trial-level meta-analyses. Yet, the routine use of this treatment remains controversial.
Yaseen Arabi, Sylvie Chevret, Laurent Billot, Anthony Gordon, Didier Keh, Romain Pirracchio, Balasubramanian Venkatesh, Djillali Annane, Andre Waschka, Jeremy Cohen, Simon Finfer, Naomi Hammond, John Myburgh, Anthony Delaney, Pierre Edouard Bollaert, Josef Briegel, Ling Liu, G Umberto, Liliana Mirea, L Charles, Nejla Tilouche, Surat Tongyoo, Ruiqiang Zheng   +22 more
doaj   +1 more source

Effect of hydrocortisone on the 28-day mortality of patients with septic acute kidney injury

Renal Failure, 2019
Objectives: To evaluate the efficacy of hydrocortisone in patients with septic acute kidney injury (SAKI). Methods: This retrospective cohort study consisted of all consecutive patients with SAKI who were admitted to the Taizhou First People's Hospital ...
Pan Ying, Chenguang Yang, Xianlong Wu, Qiqi Cai, Wenwei Xin   +4 more
doaj   +1 more source

A comparative randomized clinical trial evaluating the efficacy and safety of tacrolimus versus hydrocortisone as a topical treatment of atopic dermatitis in children

Frontiers in Pharmacology, 2023
Background: Atopic dermatitis (AD) aetiology is not exactly identified, but it is characterized by pruritic skin reactions with elevation in the levels of inflammatory markers.
Amal A. Mohamed, Radwa El Borolossy, Eman M. Salah, Maha S. Hussein, Nashwa M. Muharram, Naglaa Elsalawy, Mona G. Khalil, Maha O. Mahmoud, Reham Y. El-Amir, Heba M. A. Elsanhory, Nourelhuda Ahmed, Ahmed S. Adaroas, Mahmoud Montaser, Amal A. El Kholy   +13 more
doaj   +1 more source