Results 31 to 40 of about 123,936 (336)

Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression [PDF]

, 2012
Background: Endocannabinoids (ECs) are rapidly acting immune-modulatory lipid-signaling molecules that are important for adaptation to stressful and aversive situations. They are known to interact with glucocorticoids and other stress-responsive systems.
Beiras-Fernandez, Andres, Campolongo, Patrizia, Giehl, Markus, Hauer, Daniela, Kilger, Erich, Schelling, Gustav, Schopp, Mirjam, Strewe, Claudia, Toth, Roland, Weis, Florian   +9 more
core   +1 more source

Inhibition of canalicular and sinusoidal taurocholate efflux by cholestatic drugs in human hepatoma HepaRG cells

Biopharmaceutics &Drug Disposition, Volume 43, Issue 6, Page 265-271, December 2022., 2022
Effects of cholestatic drugs towards hepatic canalicular and sinusoidal secretion of bile acids were investigated using a biphasic functional assay in human hepatoma HepaRG cells. After an initial loading phase with taurocholate, cells were re‐incubated in taurocholate‐free medium (efflux phase), with or without calcium (for modulating the opening of ...
Marc Le Vée, Amélie Moreau, Elodie Jouan, Claire Denizot, Yannick Parmentier, Olivier Fardel   +5 more
wiley   +1 more source

Pharmacokinetic Modeling of Hydrocortisone by Including Protein Binding to Corticosteroid-Binding Globulin

Pharmaceutics, 2022
Background: Patients with adrenal insufficiency are treated with oral hydrocortisone (HC) to compensate for the loss of endogenous cortisol production. Intrinsic imperfections of cortisol replacement strategies in mimicking normal cortisol secretion are ...
Eric Rozenveld, Nieko Punt, Martijn van Faassen, André P. van Beek, Daan J. Touw   +4 more
doaj   +1 more source

Differential effects of steroids and retinoids on bovine myelopoiesis in vitro [PDF]

, 2004
Pregnancy and parturition are associated with physiological changes caused by steroid hormones. Alterations in number, maturity, and function of polymorphonuclear leukocytes observed in dairy cows at parturition suggest a common causative relationship ...
Burvenich, Christian, Duchateau, Luc, Meyer, Evelyne, VAN MERRIS, V   +3 more
core   +1 more source

A randomized clinical trial on inhaled ciclesonide for managing acute asthma in the emergency room

São Paulo Medical Journal, 2022
BACKGROUND: Use of inhaled corticosteroids for managing acute asthma exacerbations has been tested since the 1990s. OBJECTIVE: To compare high doses of inhaled ciclesonide with systemic hydrocortisone for managing acute asthma exacerbations in the ...
Demétrius Tierno Martins, Karla Carlos, Luciane Bizari Carvalho, Lucila Bizari Prado, Carolina Fransolin, Alvaro Nagib Atallah, Gilmar Fernandes do Prado   +6 more
doaj   +1 more source

Using blubber explants to investigate adipose function in grey seals:glycolytic, lipolytic and gene expression responses to glucose and hydrocortisone [PDF]

, 2017
Adipose tissue is fundamental to energy balance, which underpins fitness and survival. Knowledge of adipose regulation in animals that undergo rapid fat deposition and mobilisation aids understanding of their energetic responses to rapid environmental ...
Bennett, Kimberley A., Hall, Ailsa J., Millward, Sebastian, Moss, Simon E. W., Robinson, Kelly J.   +4 more
core   +3 more sources

Effect of Hydrocortisone vs Pasireotide on Pancreatic Surgery Complications in Patients With High Risk of Pancreatic Fistula A Randomized Clinical Trial [PDF]

, 2020
Importance Both hydrocortisone and pasireotide have been shown in randomized clinical trials to be effective in reducing postoperative complications of pancreatic surgery, but to date no randomized clinical trial has evaluated the effectiveness of ...
Kokkola, Arto, Sallinen, Ville, Siren, Jukka, Tarvainen, Timo   +3 more
core   +1 more source

Accelerated forgetting of a trauma-like event in healthy men and women after a single dose of hydrocortisone

Translational Psychiatry, 2022
Posttraumatic stress disorder (PTSD) is characterised by dysregulated hypothalamic-pituitary-adrenal axis activity and altered glucocorticoid receptor sensitivity.
Vanessa E. Hennessy, Luzia Troebinger, Georges Iskandar, Ravi K. Das, Sunjeev K. Kamboj   +4 more
doaj   +1 more source

Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants. [PDF]

, 2017
ObjectiveTo analyze reasons for low enrollment in a randomized controlled trial (RCT) of the effect of hydrocortisone for cardiovascular insufficiency on survival without neurodevelopmental impairment (NDI) in term/late preterm newborns.Study designThe ...
A Das, A F Duncan, B B Poindexter, B Carper, B J Stoll, C B Lacy, C Gauldin, C M Cotten, E F Bell, E Fernandez, G M Sokol, K A Kennedy, K L Watterberg, K P Van Meurs, M C Walsh, M H Wyckoff, M V Fraga, null null, P J Sanchez, R D Higgins, S Chawla, S Lakshminrusimha, S S Beauman, U Devaskar, W A Carlo, W E Truog, W F Buss   +26 more
core   +1 more source

Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors

ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022
Next‐generation diagnostics: Nanocarbon‐based field effect transistors (NC‐FETs) use incoming target analytes to impart a gating effect on conductance. Here, we review the operational mechanisms behind NC‐FETs, the fabrication and functionalisation of NC‐FETs with receptor biomolecules and downstream biosensing applications.
Chang‐Seuk Lee, Rebecca E. A. Gwyther, Mark Freeley, Dafydd Jones, Matteo Palma   +4 more
wiley   +1 more source