Results 41 to 50 of about 24,495 (263)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Local univalence versus stability and causality in hydrodynamic models
European Physical Journal C: Particles and FieldsOur primary goal is to compare the analytic properties of hydrodynamic series with the stability and causality conditions applied to hydrodynamic modes. Analyticity, in this context, serves as a necessary condition for hydrodynamic series to behave as a ...
Roya Heydari, Farid Taghinavaz
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Tribology Online, 2012 The optimum texturing pattern for a thrust sliding bearing of a scroll compressor was investigated. As the basis of lubrication analysis for multiple circular bumps pattern, fundamental hydrodynamic lubrication effects of the axisymmetric circular ...
Sanemasa Kawabata +4 more
doaj +1 more source
Hydrodynamic Limit of the Gross-Pitaevskii Equation [PDF]
Communications in Partial Differential Equations, 2014 We study dynamics of vortices in solutions of the Gross-Pitaevskii equation $i \partial_t u = Δu + \varepsilon^{-2} u (1 - |u|^2)$ on $\mathbb{R}^2$ with nonzero degree at infinity. We prove that vortices move according to the classical Kirchhoff-Onsager ODE for a small but finite coupling parameter $\varepsilon$.
Jerrard, Robert L., Spirn, Daniel
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Ideal-Gas Approach to Hydrodynamics
Physical Review X, 2021 Transport is one of the most important physical processes in all energy and length scales. Ideal gases and hydrodynamics are, respectively, two opposite limits of transport. Here, we present an unexpected mathematical connection between these two limits;
Zhe-Yu Shi, Chao Gao, Hui Zhai
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Journal of Marine Science and Engineering, 2021 Methods to predict underwater acoustics are gaining increased significance, as the propulsion industry is required to confirm noise spectrum limits, for instance in compliance with classification society rules.
Julian Kimmerl +2 more
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Entropy-limited hydrodynamics: a novel approach to relativistic hydrodynamics [PDF]
Computational Astrophysics and Cosmology, 2017 AbstractWe present entropy-limited hydrodynamics (ELH): a new approach for the computation of numerical fluxes arising in the discretization of hyperbolic equations in conservation form. ELH is based on the hybridisation of an unfiltered high-order scheme with the first-order Lax-Friedrichs method.
Guercilena, Federico Maria +2 more
openaire +3 more sources
Advanced Engineering Materials, EarlyView.A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares +3 more
wiley +1 more source