Results 31 to 40 of about 279,705 (272)

Generation of quasi-monoenergetic protons from thin multi-ion foils by a combination of laser radiation pressure acceleration and shielded Coulomb repulsion

open access: yesNew Journal of Physics, 2013
We study theoretically and numerically the acceleration of protons by a combination of laser radiation pressure acceleration and Coulomb repulsion of carbon ions in a multi-ion thin foil made of carbon and hydrogen.
Tung-Chang Liu   +8 more
doaj   +1 more source

pH and calcium ion release evaluation of pure and calcium hydroxide-containing Epiphany for use in retrograde filling

open access: yesJournal of Applied Oral Science, 2011
OBJECTIVE: Hydroxyl (OH-) and calcium (Ca++) ion release was evaluated in six materials: G1) Sealer 26, G2) White mineral trioxide aggregate (MTA), G3) Epiphany, G4) Epiphany + 10% calcium hydroxide (CH), G5) Epiphany + 20% CH, and G6) zinc oxide and ...
Mário Tanomaru-Filho   +3 more
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

AVALIAÇÃO DA QUALIDADE DE CREMES DERMATOLÓGICOS MANIPULADOS NA CIDADE DE MARÍLIA, SP

open access: yesColloquium Vitae, 2009
The magistral pharmacy represents an important segment in the national market of pharmacy and since the RDC 67/2007, will have to follow the new rules to guarantee more security, quality and efficacy of the manipulated formulae.
Leandra Aparecida B. Rigato   +4 more
doaj   +1 more source

HYDROGEN ION CONCENTRATIONS IN THE BLOOD OF INSECTS [PDF]

open access: yesJournal of General Physiology, 1925
The range of pH values for the blood of grasshoppers and of houseflies is 7.2 to 7.6. The range of values for roaches is 7.5 to 8.0. The range for Malacosoma americanum is 6.4 to 7.4; and the range for Bombyx mori is 6.4 to 7.2. From the work of other investigators and from the writer's results, it is apparent that the pH of insect blood, in general ...
openaire   +3 more sources

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Antigingivitis, Desensitizing, and Antiplaque Effects of Alkaline Toothpastes: A Randomized Clinical Trial

open access: yesDentistry Journal, 2023
Gingivitis is a widespread disease commonly associated with dentin hypersensitivity, that, in turn, may complicate routine dental care, leading to plaque accumulation.
Nina Novozhilova   +7 more
doaj   +1 more source

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