Results 81 to 90 of about 1,818,425 (300)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Hydrogen Embrittlement in Nb Free and Nb Microalloyed 1500 MPa Press-Hardened Steels: Mechanisms and Strain Rate Dependency

Metals
Hydrogen embrittlement (HE) critically limits the application of ultra-high-strength press-hardened steels (PHS) in hydrogen-containing environments. This study investigated the effect of Nb microalloying on HE resistance of 1500 MPa-grade PHS. Even with
Chao Lin, Maoyuan Wang, Xiaofei Guo, Xicheng Wei   +3 more
doaj   +1 more source

Tungsten-decorated MoP nanobelts for boosted hydrogen production

Materials Research Express, 2020
To further improve the electrochemical catalytic performance of MoP for hydrogen generation, a tungsten decoration strategy is proposed in this work, and the effect of preparation temperature was also investigated.
Dezhi Wang, Yao Lu, Kangyan Lv, Zhuangzhi Wu   +3 more
doaj   +1 more source

Effect of hydrogen induced decrepitation on the hydrogen sorption properties of MmNi5

International Journal of Electrochemical Science, 2020
MmNi5 hydrogen storage alloy with an average particle size of 120 μm was subjected to hydriding treatment at 50°C, under 40 atm. pure hydrogen atmosphere.
St. Todorova, V. Rangelova, L. Mihaylov, T. Spassov   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Effect of hydrogen cyanamide on bud emergence in wine grapes

California Agriculture, 1987
Results in earlier, higher budburst in Chardonnay and Cabernet grapes.
J Foott
doaj  

Study on hydrogen embrittlement susceptibility of pipeline steel under stress

You-qi chuyun
ObjectiveHydrogen embrittlement poses a significant safety risk that restricts the safe operation of hydrogen pipelines. However, there is ongoing debate regarding the extent to which hydrogen penetrates pipeline steel and induces hydrogen embrittlement ...
Cuiwei LIU, Lanqi ZHAO, Rui ZHANG, Shiyao PENG, Rongtian LI, Xinyu XU, Yuxing LI   +6 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Integration of a Hydrogen Network with the Vacuum Gas Oil Hydrocracking Reaction

Chemical Engineering Transactions, 2015
The hydrogen network of a refinery is integrated with the hydrogen consumption of Vacuum Gas Oil (VGO) hydro-cracking reactor considered. The effect of the inlet raw material and hydrogen of the VGO hydro- cracking reactor are analyzed; the quantitative ...
J. Mao, G. Liu, Y. Wang, D. Zhang
doaj   +1 more source