Results 81 to 90 of about 183,819 (280)
Design of a Nanometric AlTi Additive for MgB2-Based Reactive Hydride Composites with Superior Kinetic Properties [PDF]
, 2018 Solid-state hydride compounds are a promising option for efficient and safe hydrogen-storage systems. Lithium reactive hydride composite system 2LiBH4 + MgH2/2LiH + MgB2 (Li-RHC) has been widely investigated owing to its high theoretical hydrogen-storage
Akiba, Etsuo +17 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Characterization of Hydrogenated Natural Rubber Synthesized by Diimide Transfer Hydrogenation
International Journal of Technology, 2017 Oxidation resistance and thermal stability of natural rubber (NR) can be improved by diimide transfer hydrogenation in the latex phase. In this research, non-catalytic diimide transfer hydrogenation of concentrated NR latex was accomplished at various ...
Adi Cifriadi +2 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
"Emulsifier-regulated synthesis of nitrile rubber and its catalytic hydrogenation in emulsion"
Hecheng xiangjiao gongyeThe primary challenge in emulsion hydrogenation resides in maintaining emulsion stability under specific temperature and pressure conditions. This study proposed a strategy involving the incorporation of emulsifiers during the hydrogenation process to ...
GUO Zong-lei1 a, YU Ming-ming2, LI Yan-yan1 b, WANG Hui1 a, WANG Cheng-dong1 a
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Applied Sciences, 2017 A safe and efficient method for storing hydrogen is solid state storage through a chemical reaction in metal hydrides. A good amount of research has been conducted on hydrogenation properties of metal hydrides and possible methods to improve them ...
Shahin Shafiee +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Ambient hydrogenation of solid aromatics enabled by a high entropy alloy nanocatalyst
Nature CommunicationsHydrogenation is a versatile chemical process with significant applications in various industries, including food production, petrochemical refining, pharmaceuticals, and hydrogen carriers/safety.
Zekun Jing +13 more
doaj +1 more source