Results 151 to 160 of about 151,216 (363)

Computational Insights into the Catalytic Mechanism of Is‐PETase: An Enzyme Capable of Degrading Poly(ethylene) Terephthalate

open access: yesChemistry – A European Journal, Volume 28, Issue 70, December 15, 2022., 2022
The enzyme is‐PETase degrades poly(ethylene) terephthalate (PET) at mesophilic temperatures. This makes is‐PETase a promising candidate for the biodegradation of this common pollutant. The energy profile for the degradation of a PET substrate mimic by is‐PETase was calculated by using computational quantum‐mechanical/molecular mechanical methods, and ...
Eugene Shrimpton‐Phoenix   +2 more
wiley   +1 more source

Enzymatic Resolution of Ethyl 3-Hydroxy-3-Phenylpropanoate and Analogs using Hydrolases

open access: yesJournal of the Brazilian Chemical Society, 2001
This work contributes to the substrate model study of enzymatic hydrolysis of secondary and tertiary beta-hydroxy esters. One secondary and four tertiary beta-hydroxy esters have been employed with PCL, PLE, CRL and AOP enzymes.
Ribeiro Carlos M. R.   +2 more
doaj  

Effects of Acute Asphyxia and Deep Hypothermia on the State of Binding of Lysosomal Acid Hydrolases in Canine Cardiac Muscle [PDF]

open access: bronze, 1967
Edith G. Leighty   +4 more
openalex   +1 more source

Plant root associated chitinases: structures and functions

open access: yesFrontiers in Plant Science
Chitinases degrade chitin, a linear homopolymer of β-1,4-linked N-acetyl-D-glucosamine (GlcNAc) residues found in the cell walls of fungi and the exoskeletons of arthropods.
Samuel O. Shobade   +5 more
doaj   +1 more source

Generative Active Learning for the Search of Small-molecule Protein Binders [PDF]

open access: yesarXiv
Despite substantial progress in machine learning for scientific discovery in recent years, truly de novo design of small molecules which exhibit a property of interest remains a significant challenge. We introduce LambdaZero, a generative active learning approach to search for synthesizable molecules.
arxiv  

Thermostable glycoside hydrolases in Biorefining

open access: yes, 2014
Glycoside hydrolases, which are responsible for the degradation of the major fraction of biomass, the polymeric carbohydrates in starch and lignocellulose, are predicted to gain increasing roles as catalysts in biorefining applications in the future ...
Javier A. Linares-Pastén   +2 more
semanticscholar   +1 more source

Amylolytic glycoside hydrolases [PDF]

open access: yesCellular and Molecular Life Sciences, 2016
Štefan Janeček, Birte Svensson
openaire   +3 more sources

Stability and detectability of testosterone esters in dried blood spots after intramuscular injections

open access: yesDrug Testing and Analysis, Volume 14, Issue 11-12, Page 1926-1937, November-December 2022., 2022
We further developed the Dried Blood Spot (DBS) methodology for detection of four testosterone esters with focus on robustness and applicability in doping control. The study consisted of two parts: method development and validation, and a human administration study with intramuscular injections of 250 mg Sustanon® in healthy men.
Sara Amalie Solheim   +6 more
wiley   +1 more source

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