Results 161 to 170 of about 151,216 (363)

Hydrolase activities in differentiating plant tissues [PDF]

, 1969
John S. McLean, P. B. Gahan
openalex   +1 more source

Convergent Assembly of Homo‐ and Heterotypic Ubiquitin Chains from Functionalized, Expressed Monomers via Thiol‐Ene Chemistry

Angewandte Chemie International Edition, EarlyView.
Generating functionalized ubiquitin building blocks via expression in E. coli paves the way to different di‐, tri‐, and tetra‐ubiquitin chains. Light‐induced thiol‐ene click reactions, combined with a masking and protection strategy, are harnessed to establish controlled ubiquitin chain assembly and to allow the semisynthesis of site‐selectively ...
Moritz Urschbach, Susanne Huhmann, Dominik Appel, Luca Ferrari, Dominik Vogl, Sascha Martens, Christian F. W. Becker   +6 more
wiley   +1 more source

Influence of oxygen concentration on the metabolism of Penicillium chrysogenum

Engineering in Life Sciences, Volume 23, Issue 1, January 2023., 2023
Abstract In large‐scale bioreactors, there is often insufficient mixing and as a consequence, cells experience uneven substrate and oxygen levels that influence product formation. In this study, the influence of dissolved oxygen (DO) gradients on the primary and secondary metabolism of a high producing industrial strain of Penicillium chrysogenum was ...
Agnes Janoska, Jelle J. Verheijen, Wenjung Tang, Queenie Lee, Baukje Sikkema, Walter M. van Gulik   +5 more
wiley   +1 more source

Illuminating a biologics development challenge: systematic characterization of CHO cell-derived hydrolases identified in monoclonal antibody formulations

mAbs
Monoclonal antibodies (mAb) and other biological drugs are affected by enzymatic polysorbate (PS) degradation that reduces product stability and jeopardizes the supply of innovative medicines.
Melanie Maier, Linus Weiß, Nikolas Zeh, Valerie Schmieder-Todtenhaupt, Alireza Dehghani, Marius Nicolaus Felix, Daniel Heinzelmann, Benjamin Lindner, Moritz Schmidt, Joey Studts, Patrick Schulz, Bernd Reisinger, Kerstin Otte, Matthias Franzreb, Daniel Lakatos, Simon Fischer   +15 more
doaj   +1 more source

alpha-N-Benzoylarginine-2-naphthylamide Hydrolase (Cathepsin B1?) from Rat Skin. I. Preliminary Experiments with Skin Extract. [PDF]

, 1975
M. Järvinen, V. K. Hopsu‐Havu, Jan Rosenblom, Anna‐Britta Hörnfeldt, Rolf Servin, Hans Sternerup   +5 more
openalex   +1 more source

Polymer degrading marine Microbulbifer bacteria: an un(der)utilized source of chemical and biocatalytic novelty

Beilstein Journal of Organic Chemistry
Microbulbifer is a genus of halophilic bacteria that are commonly detected in the commensal marine microbiomes. These bacteria have been recognized for their ability to degrade polysaccharides and other polymeric materials.
Weimao Zhong, Vinayak Agarwal
doaj   +1 more source

Glycyl-l-leucine hydrolase, a versatile ‘master’ dipeptidase from monkey small intestine [PDF]

, 1973
Manjusri Das, A.N. Radhakrishnan
openalex   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Accepted Article.
Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe Bornscheuer   +4 more
wiley   +1 more source

Evidence for separate monoglyceride hydrolase and triglyceride lipase in post-heparin human plasma

, 1969
Heiner Greten, Robert I. Levy, Donald S. Fredrickson   +2 more
openalex   +1 more source

Peptide hydrolases ofBrevibacterium linens [PDF]

, 1978
Helge Torgersen, Terje SÃ ̧rhaug
openalex   +1 more source