Results 71 to 80 of about 151,216 (363)
EVALUATING THE EFFECTIVENESS OF CURETTAGE OF PERIODONTAL POCKETS ON CYTOENZIMOCHEMICAL INDICATORS
Кубанский научный медицинский вестник, 2017 The results of the study cytoenzimechemical biologically research of neutrophilic granulocytes For an assessment of efficiency of medical manipulations after curettage of periodontal pockets Average degree weight of inflammatory process.
M. S. GANDZHA +2 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Glycoside Hydrolases across Environmental Microbial Communities
PLoS Comput. Biol., 2016 Across many environments microbial glycoside hydrolases support the enzymatic processing of carbohydrates, a critical function in many ecosystems. Little is known about how the microbial composition of a community and the potential for carbohydrate ...
Renaud Berlemont, A. Martiny
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin +15 more
wiley +1 more source
The Human Ntn-Hydrolase Superfamily: Structure, Functions and Perspectives
Cells, 2022 N-terminal nucleophile (Ntn)-hydrolases catalyze the cleavage of amide bonds in a variety of macromolecules, including the peptide bond in proteins, the amide bond in N-linked protein glycosylation, and the amide bond linking a fatty acid to sphingosine ...
Arne Linhorst, Torben Lübke
doaj +1 more source
Science Advances, 2015 Therapeutic enzyme treatment disrupts Pseudomonas biofilms, potentiating antibiotics and ameliorating the innate immune system. Bacterial biofilms present a significant medical challenge because they are recalcitrant to current therapeutic regimes. A key
Perrin Baker +15 more
semanticscholar +1 more source
Micro‐ and Nano‐Bots for Infection Control
Advanced Materials, EarlyView.This review presents a strategic vision for integrating micro‐ and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on ...
Azin Rashidy Ahmady +5 more
wiley +1 more source
Journal of the American Chemical Society, 2015 Carbohydrate-active enzymes such as glycoside hydrolases (GHs) and glycosyltransferases (GTs) are of growing importance as drug targets. The development of efficient competitive inhibitors and chaperones to treat diseases related to these enzymes ...
A. Ardèvol, C. Rovira
semanticscholar +1 more source
Advanced Synthesis &Catalysis, EarlyView.Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos +5 more
wiley +1 more source
Molecules, 2018 PH46A is a single enantiomer and a member of the 1,2-indane dimer family. It has two contiguous stereogenic centers with S,S configurations, one of which being a quaternary center, which has been developed as a clinical candidate for the treatment of ...
Tao Zhang +3 more
doaj +1 more source