Pathway Dependent Isotopic Fractionation during Aerobic Biodegradation of 1,2-Dichloroethane
, 2004 1,2-Dichloroethane (1,2-DCA) is a widespread groundwater contaminant known to be biodegradable under aerobic conditions via enzymatic oxidation or hydrolytic dehalogenation reactions. Current literature reports that stable carbon isotope fractionation of
Elsner, Martin +6 more
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, 2020 The β-aryl-δ-halo-γ-lactones are known for their antiproliferative activity towards numerous cancer cell lines. The aim of this study was to obtain in the biotransformation process new β-aryl-δ-hydroxy-γ-lactones and ...
Witold Gładkowski +5 more
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Degradation of 2-Chloroallylalcohol by a Pseudomonas sp. [PDF]
, 1993 Three Pseudomonas strains capable of utilizing 2-chloroallylalcohol (2-chloropropenol) as the sole carbon source for growth were isolated from soil. The fastest growth was observed with strain JD2, with a generation time of 3.6 h.
Waarde, Jaap J. van der +5 more
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, 2016 cis-3-Chloroacrylic acid dehalogenase (cis-CaaD) catalyzes the hydrolytic dehalogenation of cis-3-haloacrylates to yield malonate semialdehyde. The enzyme processes other substrates including an allene (2,3-butadienoate) to produce acetoacetate.
Kenneth A. Johnson (519121) +5 more
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Reaction Mechanism of cis-3-Chloroacrylic Acid Dehalogenase : A Theoretical Study
, 2009 The reaction mechanism of cis-3-chloroacrylic acid dehalogenase (cis-CaaD) is studied using the B3LYP density functional theory method. This enzyme catalyzes the hydrolytic dehalogenation of cis-3-chloroacrylic acid to yield malonate semialdehyde and HCl.
Sevastik, Robin, +3 more
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The mechanistic role of catalytic residues in non-stereo dehalogenase (DehE)
, 2016 Introduction: DehE or non-stereospecific dehalogenase from Rhizobium sp. RC1 catalyzes the hydrolytic dehalogenation of both isomers of D,L-2-haloacids to produce an inverted configuration of 2-hydroxyl acid.
Abdul Hamid, Azzmer Azzar +1 more
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Novel Mechanism of Enzymatic Hydrolysis Involving Cyanoalanine Intermediate Revealed by Mass Spectrometric Monitoring of an Enzyme Reaction (MOLECULAR BIOFUNCTION-Molecular Microbial Science) [PDF]
, 2001 L-2-Haloacid dehalogenase from Pseudomonas sp. YL catalyzes the hydrolytic dehalogenation of L-2- haloalkanoic acids to produce the corresponding D-2-hydroxyalkanoic acids. Asp10 of the enzyme functions as a catalytic nucleophile: the residue attacks the
Li, Yong-Fu +3 more
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Potential of Microbial Communities to Perform Dehalogenation Processes in Natural and Anthropogenically Modified Environments-A Metagenomic Study. [PDF]
Microorganisms, 2023 Łomża P, Krucoń T, Tabernacka A.
europepmc +1 more source
, 1988 Two enzyme mechanisms were investigated: the 21-dehydroxylation of corticosteroids by Eubacterium lentum and the dehalogenation of 4-chlorobenzoic acid by Pseudomonas sp. CBS 3.
Ninniss, Ronald William.
core
Microbial Transformations of Halolactones and Evaluation of Their Antiproliferative Activity. [PDF]
Int J Mol Sci, 2023 Mazur M +3 more
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