Results 31 to 40 of about 73 (72)

Dendrimer Nanogels with Built-in Free Radical Scavenging Enable Efficient Topical Delivery of a Hydrophilic Antioxidant to Restore Lens Redox Balance for Cataract Treatment

open access: yesACS Applied Materials & Interfaces
Lin Qi   +7 more
openaire   +1 more source

Comparison of carboxybetaine with sulfobetaine polyaspartamides: Nonfouling properties, hydrophilicity, cytotoxicity and model nanogelation in an inverse miniemulsion

Journal of Applied Polymer Science, 2021
AbstractZwitterionic polymers are promising non‐fouling materials widely used for surface modification. Here, we report the synthesis of zwitterionic polyaspartamides bearing carboxybetaine and sulfobetaine prepared via combining the ring‐opening reaction of polysuccinimide with 3‐(dimethylamino)‐1‐propylamine and the reaction of the formed tertiary ...
Sviatoslav Hladysh   +7 more
openaire   +1 more source

Hydrophilic Fluorescent Nanogel Thermometer for Intracellular Thermometry

Journal of the American Chemical Society, 2009
The first methodology to measure intracellular temperature is described. A highly hydrophilic fluorescent nanogel thermometer developed for this purpose stays in the cytoplasm and emits stronger fluorescence at a higher temperature. Thus, intracellular temperature variations associated with biological processes can be monitored by this novel ...
Chie, Gota   +4 more
openaire   +2 more sources

The study of physical properties and formulation of self-assembling nanogel from grafted hydrophilic polymer backbone as stabilization system for curcumin

The Thai Journal of Pharmaceutical Sciences, 2021
Introduction: The aim of this work is to formulate and study the thermoresponsive system with hyaluronic acid (HA) as a polysaccharide backbone grafted with poly-(N-isopropylacrylamide) (pNIPAM) for stabilization of highly sensitive molecule. Methods: The nanogel forming polymer was synthesized through EDC/NHS coupling reaction.
Penpimon Charoenkanburkang   +3 more
openaire   +1 more source

Hydrophilicity/Hydrophobicity Reversable and Redox-Sensitive Nanogels for Anticancer Drug Delivery

Molecular Pharmaceutics, 2015
Long circulation in the blood, efficient cellular internalization, and intracellular drug release in the tumor cells are major challenges in the development of ideal anticancer drug delivery systems. In this paper, hydrophilicity/hydrophobicity reversable and redox-sensitive poly(oligo(ethylene glycol) methacrylates-ss-acrylic acid) (P(OEGMAs-ss-AA ...
Hao, Yang   +7 more
openaire   +2 more sources

Selective Release of Hydrophobic and Hydrophilic Cargos from Multi-Stimuli-Responsive Nanogels

ACS Applied Materials & Interfaces, 2016
Highly stable multi-stimuli-responsive nanogels for selective release of simultaneously encapsulated hydrophobic and hydrophilic cargos in a spatiotemporally controlled manner are demonstrated here. The nanogel is composed of hydrophilic pH- and thermoresponsive poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) and hydrophobic photocleavable o ...
Ziquan, Cao   +2 more
openaire   +2 more sources

Design of hydrophilic photocleavage o-nitrobenzyl acrylate-modified nanogels with outstanding biocompatibility prepared by RAFT polymerization for drug carrier

European Polymer Journal, 2020
Abstract Three kinds of hydrophilic photocleavage o-nitrobenzyl acrylate-modified nanogels with different particle size and narrow particle size distribution (1.8–0.24) were designed and synthesized by reversible addition-fragmentation chain transfer radical (RAFT) polymerization based on methoxy polyethylene glycol methacrylate (MPEGMA) and UV-light
Fuhua Xin   +6 more
openaire   +1 more source

Design of photoinitiator-functionalized hydrophilic nanogels with uniform size and excellent biocompatibility

Polymer Chemistry, 2019
Three well-controlled biocompatible hydrophilic nanogels were synthesized, and they can effectively initiate photopolymerization and improve the mechanical properties of polymers.
Meng Wei   +4 more
openaire   +1 more source

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