Results 41 to 50 of about 73 (72)

Covalent-bonded immobilization of enzyme on hydrophilic polymer covering magnetic nanogels

Microporous and Mesoporous Materials, 2008
Abstract A new mesoporous support, hydrophilic polymer covering magnetic nanogels containing reactive carboxyl groups, was obtained by photochemical in situ polymerization. The enzyme α-chymotrypsin (CT), a model for protein or esters hydrolysis, was anchored to the support by 1-ethyl-3-(3-dimethylaminepropyl) carbodiimide (EDC) activation.
Jun Hong, Dongmei Xu, Peijun Gong, Jiahui Yu, Hongjuan Ma, Side Yao   +5 more
openaire   +1 more source

Core cross-linked nanogels based on the self-assembly of double hydrophilic poly(2-oxazoline) block copolymers

Journal of Materials Chemistry B, 2015
The synthesis of poly(2-oxazoline)-based block copolymers consisting of a cationic and a hydrophilic segment is described.
Matthias, Hartlieb, David, Pretzel, Michael, Wagner, Stephanie, Hoeppener, Peter, Bellstedt, Matthias, Görlach, Christoph, Englert, Kristian, Kempe, Ulrich S, Schubert   +8 more
openaire   +2 more sources

Abstract 3099: pH-regulated hydrophilicity/hydrophobicity-, surface charge-reversible and redox sensitive nanogels for anticancer drug delivery

Cancer Research, 2017
Abstract Long circulation in blood, enhanced tumor accumulation and penetration, efficient cellular internalization and intracellular drug release are major challenges in the development of ideal anticancer drug delivery systems. Although several strategies have been reported to improve therapeutic efficacy, they mainly meet one or a few
Hao Yang, Qin Wang, Fuying Li, Yanhong Zhu, Lu Gan, Xiangliang Yang   +5 more
openaire   +1 more source

A novel thermo-sensitive nanogel composing of poly(N-isopropylacrylamide) grafted onto alginate-modified graphene oxide for hydrophilic anticancer drug delivery

Journal of the Iranian Chemical Society, 2017
Nanogels have been demonstrated to be desirable for hydrophilic anticancer drug delivery. This study presents a novel nanogel consisting of sodium alginate-modified graphene oxide (SA-GO) and N-isopropylacrylamide (NIPAM) for sustained delivery of doxorubicin (DOX) drug.
Ghasem Rezanejade Bardajee, Zari Hooshyar   +1 more
openaire   +1 more source

Hydrophilic Nanogels : Characterization and Behavior in Biological Environment

2011
Hydrophilic nanocarriers, formed by electrostatic interaction between their oppositely charged components, are recognized as nanomaterials with an enormous potential as vectors in biomedical and pharmaceutical applications. However, comprehensive information about their fate in various biological environments is still lacking.
openaire   +1 more source

STIMULI RESPONSIVE POLYMERIC NANOGELS FOR HYDROPHOBICS & HYDROPHILICS DELIVERY

2017
This thesis will be focused on the thin film self-assembly and high resolution nanolithography of lamellae-forming PS-b-P2VP block copolymer. Some of the scientific and engineering problems of block copolymer self-assembly will be studied using the state-of-the-art characterization facilities including AFM, SEM and synchrotron radiation X-ray ...
openaire   +1 more source

Integrating encapsulation and self-assembly-induced disulfide cross-linking: a universal strategy for preparing hydrophilic guest-loaded responsive hyperbranched polyglycerol nanogels

Polymer Chemistry
We report a universal method for preparing hydrophilic guest-loaded responsive nanogels (NGs) by combining the encapsulation advantages of amphiphilic HPG-LA with its capability to form NGs by self-assembly-induced disulfide cross-linking.
Hai Zeng, Qingli Chen, Li Zhou
openaire   +1 more source

Macromolecular design of pH sensitive, folic acid functionalized double hydrophilic block copolymer nanogels as methotrexate carriers to breast cancer cells

Journal of Drug Delivery Science and Technology, 2023
Mohammadreza Ghaffarlou, S. Duygu Sütekin, Hamideh Hammamchi, Murat Barsbay   +3 more
openaire   +1 more source

Nanogel fabricated from oxidized sodium alginate and hydrophilic-modified chitosan exhibits great potential as pH-responsive drug delivery system

Journal of the Iranian Chemical Society, 2022
Dawei Qin, Fang Wang, Wenlong Sheng, Shuhua Chang, Hongdong Duan, Lizhen Wang   +5 more
openaire   +1 more source

Photocontrollable viscosity and hydrophilicity of nanogel based antibacterial dental adhesives

Dental Materials, 2019
G. Kehe, R. Trivedi, K. Patel, D. Nair
openaire   +1 more source