Cytotoxic Compounds of Two Demosponges (Aplysina aerophoba and Spongia sp.) from the Aegean Sea
Biomolecules, 2021 The class of demosponges is the biggest and most diverse of all described sponge species and it is reported to produce a plethora of chemically different metabolites with interesting biological activities.
Maria Orfanoudaki +9 more
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Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone [PDF]
, 2020 Alterations in the NRF2/KEAP1 pathway result in the constitutive activation of NRF2, leading to the aberrant induction of antioxidant and detoxification enzymes, including NQO1.
Boothman, David A. +6 more
core +1 more source
Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones [PDF]
Journal of the Serbian Chemical Society, 2002 The regioselectivity of the reaction of conjugate addition of thiols, amines, methanol and hydrogen chloride with the monoalkyl-1,4-benzoquinones avarone and 2-tert-butyl-1,4-benzoquinone was investigated.
SNEZANA TRIFUNOVIC +5 more
doaj +3 more sources
Microbiology Spectrum, 2022 Candida albicans is an opportunistic pathogenic fungus responsible for candidiasis. The pathogen readily forms antifungal agent-resistant biofilms on implanted medical devices or human tissue.
Yong-Guy Kim +5 more
doaj +1 more source
Synthetic Strategies to Terpene Quinones/Hydroquinones
Marine Drugs, 2012 The cytotoxic and antiproliferative properties of many natural sesquiterpene-quinones and -hydroquinones from sponges offer promising opportunities for the development of new drugs.
Marina Gordaliza
doaj +1 more source
Norhierridin B, a New Hierridin B-Based Hydroquinone with Improved Antiproliferative Activity
Molecules, 2020 Hierridin B (6), a methylated hydroquinone isolated from the marine picocyanobacterium Cyanobium sp. LEGE 06113, moderately inhibited the growth of colon adenocarcinoma HT-29 cells.
Pedro Brandão +10 more
doaj +1 more source
Meroterpenes from marine invertebrates: structures, occurrence, and ecological implications [PDF]
, 2013 Meroterpenes are widely distributed among marine organisms; they are particularly abundant within brown algae, but other important sources include microorganisms and invertebrates.
AIELLO, ANNA +3 more
core +2 more sources
Generation of superoxide and singlet oxygen from α-tocopherolquinone and analogues. [PDF]
, 2007 Three potential routes to generation of reactive oxygen species from a tocopherolquinone have been identified. The quinone of the water-soluble vitamin E analogue Trolox C (Trol-Q) is reduced by hydrated electron and isopropanol a hydroxyalkyl radical ...
Bisby, RH +4 more
core +1 more source
Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium
Marine Drugs, 2014 Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones.
Camila Spereta Bertanha +6 more
doaj +1 more source
Laccase-Catalyzed Derivatization of Antibiotics with Sulfonamide or Sulfone Structures
Microorganisms, 2021 Trametes spec. laccase (EC 1.10.3.2.) mediates the oxidative coupling of antibiotics with sulfonamide or sulfone structures with 2,5-dihydroxybenzene derivatives to form new heterodimers and heterotrimers. These heteromolecular hybrid products are formed
Annett Mikolasch, Veronika Hahn
doaj +1 more source