Exerting DNA Damaging Effects of the Ilimaquinones through the Active Hydroquinone Species
Scientia Pharmaceutica, 2021 Possessing the quinone moiety, ilimaquinone (1), a sponge–derived sesquiterpene quinone, has been hypothesised to express its cytotoxicity through a redox cycling process, yielding active product(s) that can cause DNA damage.
Apisada Jiso +4 more
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Cytotoxic Compounds of Two Demosponges (Aplysina aerophoba and Spongia sp.) from the Aegean Sea
Biomolecules, 2021 The class of demosponges is the biggest and most diverse of all described sponge species and it is reported to produce a plethora of chemically different metabolites with interesting biological activities.
Maria Orfanoudaki +9 more
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Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones [PDF]
Journal of the Serbian Chemical Society, 2002 The regioselectivity of the reaction of conjugate addition of thiols, amines, methanol and hydrogen chloride with the monoalkyl-1,4-benzoquinones avarone and 2-tert-butyl-1,4-benzoquinone was investigated.
SNEZANA TRIFUNOVIC +5 more
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Microbiology Spectrum, 2022 Candida albicans is an opportunistic pathogenic fungus responsible for candidiasis. The pathogen readily forms antifungal agent-resistant biofilms on implanted medical devices or human tissue.
Yong-Guy Kim +5 more
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Norhierridin B, a New Hierridin B-Based Hydroquinone with Improved Antiproliferative Activity
Molecules, 2020 Hierridin B (6), a methylated hydroquinone isolated from the marine picocyanobacterium Cyanobium sp. LEGE 06113, moderately inhibited the growth of colon adenocarcinoma HT-29 cells.
Pedro Brandão +10 more
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Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium
Marine Drugs, 2014 Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones.
Camila Spereta Bertanha +6 more
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Laccase-Catalyzed Derivatization of Antibiotics with Sulfonamide or Sulfone Structures
Microorganisms, 2021 Trametes spec. laccase (EC 1.10.3.2.) mediates the oxidative coupling of antibiotics with sulfonamide or sulfone structures with 2,5-dihydroxybenzene derivatives to form new heterodimers and heterotrimers. These heteromolecular hybrid products are formed
Annett Mikolasch, Veronika Hahn
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Reduction of Benzoquinones to Hydroquinones via Spontaneous Reaction with Glutathione and Enzymatic Reaction by S-Glutathionyl-Hydroquinone Reductases [PDF]
, 2016 S-Glutathionyl-hydroquinone reductases (GS-HQRs) are a new class of glutathione transferases, widely present in bacteria, halobacteria, fungi, and plants.
Lam , L.K. Metthew +3 more
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2-Amino-4-(4-methoxyphenyl)-1-(4-methylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile
IUCrData, 2018 In the title compound, C24H23N3O2, the cyclohexene and 1,4-dihydropyridine rings of the 1,4,5,6,7,8-hexahydroquinoline ring system each adopt a twisted-boat conformation. The dihedral angle between the benzene rings is 13.89 (10)°.
Asmaa H. A. Tamam +5 more
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Cytotoxic Terpene Quinones from Marine Sponges
Marine Drugs, 2010 The 1,4-benzoquinone moiety is a common structural feature in a large number of compounds that have received considerable attention owing to their broad spectrum of biological activities.
Marina Gordaliza
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