Results 1 to 10 of about 4,512 (175)

Hydroxocobalamin For The Treatment Of Vasoplegia After Lung Transplantation: A Case Series [PDF]

JHLT Open
Background: The use of hydroxocobalamin following lung transplantation has not been previously reported. We present a series of 3 cases where hydroxocobalamin was used to treat postoperative vasoplegia.
Anh Tuấn Nguyễn, Rima Bouajram, Marek Brzeziński, Soheil Hassanipour, David E. Gordon, B. Trinh, T. Deuse, Aida Venado, S.R. Hays, Jonathan P. Singer, Jasleen Kukreja   +10 more
doaj   +7 more sources

Vitamin B12 (hydroxocobalamin) administration in the management of persistent vasoplegic shock [PDF]

Saudi Journal of Anaesthesia
Vasoplegia, characterized by low systemic vascular resistance despite normal to high cardiac output, can result from various conditions, including cardiac surgery, and progress to vasoplegic shock if untreated.
Jibran Ikram, Cassandra L. Williams, Aariya Srinivasan, Jose L Diz Ferre, Sabry Ayad   +4 more
doaj   +4 more sources

A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias [PDF]

Journal of Pain Research, 2017
Henrique Goldberg,1 Marco Antonio Mibielli,2 Carlos Pereira Nunes,2 Stephanie Wrobel Goldberg,3 Luiz Buchman,4 Spyros GE Mezitis,5 Helio Rzetelna,6 Lisa Oliveira,2 Mauro Geller,2 Fernanda Wajnsztajn7 1UERJ Medical School, Rio de Janeiro, Brazil; 2UNIFESO
Goldberg H, Mibielli MA, Nunes CP, Goldberg SW, Buchman L, Mezitis SG, Rzetelna H, Oliveira L, Geller M, Wajnsztajn F   +9 more
doaj   +3 more sources

Rapid Improvement of Hyperpigmentation, Growth, and Developmental Milestones With High‐Dose Hydroxocobalamin, Betaine, and Folinic Acid Treatment: The First Patient With Cobalamin G Deficiency in Taiwan [PDF]

JIMD Reports
In this report, we present the case of a 16‐month‐old patient who was diagnosed with cobalamin G deficiency at 4 months of age via whole exome sequencing by detecting compound heterozygous variants of uncertain significance (VUS) in the MTR gene: (1) c ...
Chang‐Che Wu, Sin-Tuan Huang, Chu‐Chin Chen, Pao‐Chin Chiu   +3 more
doaj   +3 more sources

Vitamin B12 status in infancy and the effect of a vitamin B12 injection in infants with subclinical vitamin B12 deficiency: study protocol for a register-based randomised controlled trial [PDF]

BMJ Open, 2023
Introduction Vitamin B12 (cobalamin) is crucial for optimal child development and growth, yet deficiency is common worldwide. The aim of this study is twofold; (1) to describe vitamin B12 status and the status of other micronutrients in Norwegian infants,
Ingrid Kvestad, Tor A Strand, Elisabeth Ersvær, Siri Kaldenbach, Beate Stokke Solvik, Kjersti S Bakken, Sol Maja Graasvold Bjørkevoll, Adrian McCann, Mads Nikolaj Holten-Andersen, Carolien Konijnenberg   +9 more
doaj   +3 more sources

Intramuscular Vitamin B12 Treatment in Transcobalamin II Deficiency: Case Series Clinical Outcomes [PDF]

The Application of Clinical Genetics
Ali M Sawlan,1 Msaed Alotaibi,1 Rayan M Alharbi,1 Nimr A Alwahbi,1 Manar Alshammary,2 Ali Mohammad Alasmari,2 Fuad Al Mutairi3,4 1College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs (MNG ...
Sawlan AM, Alotaibi M, Alharbi RM, Alwahbi NA, Alshammary M, Alasmari AM, Al Mutairi F   +6 more
doaj   +2 more sources

An In Vitro Model of Gastric Inflammation and Treatment with Cobalamin [PDF]

International Journal of Inflammation, 2017
Pernicious anaemia (PA) is an autoimmune condition where antibodies target intrinsic factor and parietal cells, reducing the patient’s ability to absorb cobalamin promoting atrophic gastritis.
T. R. Elliott, A. L. Guildford
doaj   +4 more sources

Late‐onset refractory hemolytic anemia in siblings treated for methionine synthase reductase deficiency: A rare complication possibly prevented by hydroxocobalamin dose escalation? [PDF]

JIMD Reports
Methionine synthase reductase deficiency (cblE) is a rare autosomal recessive inborn error of cobalamin metabolism caused by pathogenic variants in the methionine synthase reductase gene (MTRR).
Alexandre Nguyen, Samuel Deshayes, Marie Nowoczyn, Apolline Imbard, Lamisse Mansour‐Hendili, Alexandre Cesbron, Jean François Benoist, Manuel Schiff   +7 more
doaj   +2 more sources

Clinical diagnosis, treatment, and genetic analysis of adolescent onset holocarboxylase synthetase deficiency and cobalamin C deficiency: A case report and literature review [PDF]

Metabolism Open
Background: Holocarboxylase Synthetase Deficiency (HCSD) is an uncommon autosomal recessive genetic disorder that manifests with symptoms such as metabolic acidosis, lethargy, hypotonia, seizures, and persistent rashes, typically emerging during infancy.
Ye Ren, Hongxing Dang, Yueqiang Fu, Chengjun Liu, Jing Li, Jinhua Cai   +5 more
doaj   +2 more sources

Complete Immunophenotypic Reversal of Chronic Lymphocytic Leukaemia With High Dose Parenteral Methylcobalamin: A Case Report and Brief Review of Cobalamin in Cancer [PDF]

Cancer Reports
Background Supposed ‘spontaneous’ remissions in chronic lymphocytic leukaemia (CLL) are extremely rare. By the most stringent immunophenotypic criteria, there are only seven cases to date of unexplained, immune system effected cures. A historic review of
Carmen Wheatley
doaj   +2 more sources