Results 21 to 30 of about 4,512 (175)
The voltammetric behavior of hydroxocobalamin (OH-CBL) was firstly studied by employing a bare boron-doped diamond electrode as a working electrode. It was found that OH-CBL provided four anodic signals on BDDE in acidic supporting electrolytes and one ...
Lenka Janíková+3 more
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579 Incidence of Acute Kidney Injury with Hydroxocobalamin Administration [PDF]
Adalah Yahia+3 more
openalex +2 more sources
Cobalamin C (cblC) deficiency is the most common inborn error of intracellular cobalamin metabolism caused by pathogenic variant(s) in MMACHC and manifests with methylmalonic acidemia, hyperhomocysteinemia, and hypomethioninemia with a variable age of ...
Tomoyasu Higashimoto+9 more
doaj +1 more source
Pediatric Cyanide Poisoning After Ingestion of Apricot Seeds
Cyanide is one of the strongest and lethal poisons. Cyanide leads to tissue hypoxia and lactic acid accumulation. Hydroxocobalamin is a safe, fast and effective antidote that could be used, especially in children.
Yüksel Bıcılıoğlu+3 more
doaj +1 more source
Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction
TAR DNA-binding protein 43 (TDP-43) is a member of an evolutionarily conserved family of heterogeneous nuclear ribonucleoproteins that modulate multiple steps in RNA metabolic processes.
Yu-Mi Jeon+8 more
doaj +1 more source
Vitamin B12 or cobalamin deficiency is a commonly encountered clinical scenario and most clinicians will have familiarity prescribing Vitamin B12 to treat their patients.
Ramyia Elangovan+3 more
doaj +1 more source
Vitamin B12, also known as the anti-pernicious anemia factor, is an essential micronutrient totally dependent on dietary sources that is commonly integrated with food supplements.
Žane Temova Rakuša+3 more
doaj +1 more source
Midazolam Efficacy Against Acute Hydrogen Sulfide-Induced Mortality and Neurotoxicity. [PDF]
Hydrogen sulfide (H2S) is a colorless, highly neurotoxic gas. It is not only an occupational and environmental hazard but also of concern to the Department of Homeland Security for potential nefarious use. Acute high-dose H2S exposure causes death, while
Anantharam, Poojya+6 more
core +1 more source
Transient Transcriptional Regulation of the CYS-C1 Gene and Cyanide Accumulation upon Pathogen Infection in the Plant Immune Response [PDF]
Cyanide is produced concomitantly with ethylene biosynthesis. Arabidopsis (Arabidopsis thaliana) detoxifies cyanide primarily through the enzyme b-cyanoalanine synthase, mainly by the mitochondrial CYS-C1.
Bejarano, Eduardo R.+3 more
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Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]
FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R.+9 more
core +1 more source