Results 21 to 30 of about 8,578 (226)

Complete Immunophenotypic Reversal of Chronic Lymphocytic Leukaemia With High Dose Parenteral Methylcobalamin: A Case Report and Brief Review of Cobalamin in Cancer. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Supposed ‘spontaneous’ remissions in chronic lymphocytic leukaemia (CLL) are extremely rare. By the most stringent immunophenotypic criteria, there are only seven cases to date of unexplained, immune system effected cures. A historic review of this phenomenon is presented as context for this eighth case of CLL immunophenotypic ...
Wheatley C.
europepmc   +2 more sources

Hydroxocobalamin for Vasodilatory Hypotension in Shock: A Systematic Review With Meta-Analysis for Comparison to Methylene Blue.

Journal of Cardiothoracic and Vascular Anesthesia, 2023
Hydroxocobalamin inhibits nitric oxide-mediated vasodilation, and has been used in settings of refractory shock. However, its effectiveness and role in treating hypotension remain unclear.
Hannah M. Brokmeier, Troy G. Seelhammer, Scott D. Nei, Danielle J. Gerberi, K. Mara, E. Wittwer, P. Wieruszewski   +6 more
semanticscholar   +1 more source

Watching Excited State Dynamics with Optical and X-ray Probes: The Excited State Dynamics of Aquocobalamin and Hydroxocobalamin.

Journal of the American Chemical Society, 2023
Femtosecond time-resolved X-ray absorption (XANES) at the Co K-edge, X-ray emission (XES) in the Co Kβ and valence-to-core regions, and broadband UV-vis transient absorption are combined to probe the femtosecond to picosecond sequential atomic and ...
R. Sension, Taylor P. McClain, Ryan M. Lamb, R. Alonso-Mori, F. Lima, F. Ardana-Lamas, M. Biednov, M. Chollet, Taewon Chung, A. Deb, Paul A Dewan, Leland B. Gee, Joel Huang Ze En, Yifeng Jiang, D. Khakhulin, Jianhao Li, Lindsay B Michocki, Nicholas A. Miller, F. Otte, Y. Uemura, T. V. van Driel, J. Penner‐Hahn   +21 more
semanticscholar   +1 more source

Spectrophotometric analysis of purple urine secondary to methylene blue and hydroxocobalamin co-administration

JN. Journal of Nephrology (Milano. 1992), 2023
Background The development of purple urine after methylene blue (methylthioninium chloride) and hydroxocobalamin co-administration is a rare clinical entity that has not been fully elucidated. A 47-year-old male presented to the emergency department with
Jeremy Hardin, Henrik Galust, R. Clark, B. Ly, Raymond T. Suhandynata   +4 more
semanticscholar   +1 more source

Comparison of hydroxocobalamin with other resuscitative fluids in volume-controlled and uncontrolled hemorrhage models in swine (Sus-scrofa)

Journal of Trauma and Acute Care Surgery, 2023
Hydroxocobalamin was evaluated as possible resuscitation fluid, compared to clinically relevant resuscitation fluids, in pre-clinical models of controlled and uncontrolled hemorrhage.
PhD R. Madelaine Paredes, MS Maria Castaneda, PhD Allyson A. Mireles, MS Dylan Rodriguez, MD Joseph Maddry, Joint Base, San Antonio-Lackland   +6 more
semanticscholar   +1 more source

Severe Vasoplegic Syndrome Treated with Angiotensin II and Hemoadsorption Therapy after Cardiac Surgery. [PDF]

Catheter Cardiovasc Interv
ABSTRACT Vasoplegic syndrome (VS) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). The main pathophysiology mechanism of VS includes a systemic inflammatory response syndrome due to surgical trauma, release of pro‐inflammatory mediators caused by blood contact with foreign surfaces of heart‐lung machine (pump and tubing)
Lucchelli M, Andreis DT, Gomarasca M, Mistraletti G.   +3 more
europepmc   +2 more sources

Analysis of Methylcobalamin and Hydroxocobalamin by HPLC/MS. Method Validation

Scholars Academic Journal of Pharmacy, 2023
Previously, we found that methylcobalamin spontaneously converts to hydroxocobalamin at room temperature in aqueous and methanol solutions protected from light. The kinetics and rate constants were determined.
Stanislav V. Yefimov
semanticscholar   +1 more source

Midazolam Efficacy Against Acute Hydrogen Sulfide-Induced Mortality and Neurotoxicity. [PDF]

, 2018
Hydrogen sulfide (H2S) is a colorless, highly neurotoxic gas. It is not only an occupational and environmental hazard but also of concern to the Department of Homeland Security for potential nefarious use. Acute high-dose H2S exposure causes death, while
Anantharam, Poojya, Imerman, Paula, Kim, Dong-Suk, Mahama, Belinda, Padhi, Piyush, Rumbeiha, Wilson K, Whitley, Elizabeth M   +6 more
core   +1 more source

A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias [PDF]

, 2017
CONTEXT: This paper reports on the results of treatment of compressive neuralgia using a combination of nucleotides (uridine triphosphate trisodium [UTP] and cytidine monophosphate disodium [CMP]) and vitamin B(12).
Buchman, Luiz, Geller, Mauro, Goldberg, Henrique, Goldberg, Stephanie Wrobel, Mezitis, Spyros GE, Mibielli, Marco Antonio, Nunes, Carlos Pereira, Oliveria, Lisa, Rzetelna, Helio, Wajnsztajn, Fernanda   +9 more
core   +2 more sources

Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]

, 2018
FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R., Burrage, Lindsay C., Craigen, William J., Emrick, Lisa, Freeze, Hudson H., Graham, Brett H., Jain, Mahim, Lee, Brendan, Ng, Bobby G., Rosenfeld, Jill A.   +9 more
core   +1 more source