Results 41 to 50 of about 7,137 (264)

Vitamin B₁₂ in Foods, Food Supplements, and Medicines—A Review of Its Role and Properties with a Focus on Its Stability

Molecules, 2022
Vitamin B12, also known as the anti-pernicious anemia factor, is an essential micronutrient totally dependent on dietary sources that is commonly integrated with food supplements.
Žane Temova Rakuša, Robert Roškar, Neal Hickey, Silvano Geremia   +3 more
doaj   +1 more source

Midazolam Efficacy Against Acute Hydrogen Sulfide-Induced Mortality and Neurotoxicity. [PDF]

, 2018
Hydrogen sulfide (H2S) is a colorless, highly neurotoxic gas. It is not only an occupational and environmental hazard but also of concern to the Department of Homeland Security for potential nefarious use. Acute high-dose H2S exposure causes death, while
Anantharam, Poojya, Imerman, Paula, Kim, Dong-Suk, Mahama, Belinda, Padhi, Piyush, Rumbeiha, Wilson K, Whitley, Elizabeth M   +6 more
core   +1 more source

Analysis of Methylcobalamin and Hydroxocobalamin by HPLC/MS. Method Validation

Scholars Academic Journal of Pharmacy, 2023
Previously, we found that methylcobalamin spontaneously converts to hydroxocobalamin at room temperature in aqueous and methanol solutions protected from light. The kinetics and rate constants were determined.
Stanislav V. Yefimov
semanticscholar   +1 more source

Inherited and acquired vitamin B12 deficiencies: Which administration route to choose for supplementation?

Frontiers in Pharmacology, 2022
Vitamin B12 or cobalamin deficiency is a commonly encountered clinical scenario and most clinicians will have familiarity prescribing Vitamin B12 to treat their patients.
Ramyia Elangovan, Julien Baruteau, Julien Baruteau, Julien Baruteau   +3 more
doaj   +1 more source

Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]

, 2018
FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R., Burrage, Lindsay C., Craigen, William J., Emrick, Lisa, Freeze, Hudson H., Graham, Brett H., Jain, Mahim, Lee, Brendan, Ng, Bobby G., Rosenfeld, Jill A.   +9 more
core   +1 more source

Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

Antioxidants, 2021
TAR DNA-binding protein 43 (TDP-43) is a member of an evolutionarily conserved family of heterogeneous nuclear ribonucleoproteins that modulate multiple steps in RNA metabolic processes.
Yu-Mi Jeon, Younghwi Kwon, Shinrye Lee, Seyeon Kim, Myungjin Jo, Seongsoo Lee, Sang Ryong Kim, Kiyoung Kim, Hyung-Jun Kim   +8 more
doaj   +1 more source

The availability of therapeutic hydroxocobalamin to cells [PDF]

Blood, 1984
Abstract Hydroxocobalamin (OH-Cbl), when used to treat vitamin B12 deficiency, is better retained by the body than is cyanocobalamin (CN-Cbl), but the availability to cells has not been studied systematically. In a series of experiments, we compared the uptake and internalization of OH-Cbl and CN-Cbl bound to transcobalamin II (TCII) by ...
Charles A. Hall, Pamela D. Green-Colligan, James A. Begley   +2 more
openaire   +4 more sources

A New, Atypical Case of Cobalamin F Disorder Diagnosed by Whole Exome Sequencing [PDF]

, 2015
The Deciphering Developmental Disorders Study presents independent research commissioned by the Health Innovation Challenge Fund (HICF-1009-003), a parallel funding partnership between the Wellcome Trust and the Department of Health, and the Wellcome ...
Constantinou, Panayiotis, D'Allesandro, Mariella, Dean, John, Deciphering Developmental Disorders Study, Hauptfleisch, Catherine, Lochhead, Paul, Samant, Shalaka   +6 more
core   +1 more source

Vitamin B12 induced acneiform eruption

Heliyon, 2023
A 47-year-old, north african, male patient, has recently been diagnosed with pernicious anemia, treated with weekly intramuscular hydroxocobalamin.
Imane Bahbouhi, Maryem Aboudourib, Ouafa Hocar, Said Amal   +3 more
doaj   +1 more source

Cyanide Production by Chromobacterium piscinae Shields It from Bdellovibrio bacteriovorus HD100 Predation [PDF]

, 2017
Predation of Chromobacterium piscinae by Bdellovibrio bacteriovorus HD100 was inhibited in dilute nutrient broth (DNB) but not in HEPES. Experiments showed that the effector responsible was present in the medium, as cell-free supernatants retained the ...
Aruldass, August, Ballestriero, Bansal, Blom, Blumer, Brysk, Burlinson, Castric, Castric, Choi, Dwidar, Faust, Frangipani, Friedberg, Gallagher, Guilbault, Hakvåg, Hoshino, Im, Jousset, Jurkevitch, Karlin, Lambert, Leavesley, Lee, Lee, Lee, Lichstein, Masuelli, Matz, Matz, Matz, Michaels, Michaels, Monnappa, Moss, Mukherjee, Nagai, Neidig, Niven, Pantanella, Pernthaler, Pradel, Pujol, Riou, Riveros, Roschanski, Shepherd, Siddiqui, Simpson, Subramaniam, Swem, Tomlin, Tsuchido, Wang, Wissing, Wrede   +57 more
core   +2 more sources