Receiving a diagnosis of Pernicious Anaemia: exploring experiences of relationships with health professionals [PDF]
Objectives: Pernicious Anaemia (PA) is a chronic condition caused by vitamin B12 deficiency. This is a qualitative study using interpretative phenomenological analysis (IPA); which aimed to explore the patients lived experience of diagnosis and ...
Glover, E., Mercer, Jenny, Seage, Heidi
core +1 more source
Sodium nitroprusside-induced activation of vascular smooth muscle BK channels is mediated by PKG rather than by a direct interaction with NO [PDF]
Nitric oxide (NO) is a powerful vasodilator in different vascular beds and NO-donors are widely used in clinical practice. Early data suggested that NO and NO-donors activate vascular smooth muscle high-conductance, calcium-activated potassium channels ...
Gagov, Hristo+3 more
core +1 more source
Vasoplegic syndrome, a possible complication of cardiopulmonary bypass, is a critical state of unregulated systemic vasodilation with decreased vascular resistance and a pathological insensitivity to conventional inotropes and vasoconstrictors. This case
Jacob Lambert+8 more
doaj +1 more source
Protocol Compliance Guiding Angiotensin II Use in Post Cardiovascular Surgery Vasoplegia
OBJECTIVES:. Catecholamines and vasopressin are commonly used in patients with post cardiovascular surgery vasoplegia (PCSV). Multimodal therapy, including methylene blue (MB), hydroxocobalamin, and angiotensin II (Ang II), may improve outcomes in ...
Caitlin C. ten Lohuis, MSN, ACNP-BC+5 more
doaj +1 more source
Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1 beta, TNF-alpha, IL-6, and HMGB1 Expression [PDF]
Background. NOS/•NO inhibitors are potential therapeutics for sepsis, yet they increase clinical mortality. However, there has been no in vivo investigation of the (in vitro) •NO scavenger, cobalamin’s (Cbl) endogenous effects on NOS/•NO/inflammatory ...
Brancaleone, V+5 more
core +3 more sources
Spectrophotometric Analysis of Purple Urine Secondary to Methylene Blue and Hydroxocobalamin Co-Administration [PDF]
BACKGROUND: The development of purple urine after methylene blue (methylthioninium chloride) and hydroxocobalamin co-administration is a rare clinical entity that has not been fully elucidated.
Clark, Richard Franklin+4 more
core +2 more sources
Cyanide in breath as a marker for cyanide poisoning [PDF]
Approximately 120 people die every year due to fires in Sweden. A majority of the fire victims die due to toxic fire gases. Carbon monoxide is often thought to be the major cause of death. Still, another very toxic fire gas, hydrogen cyanide, is formed
Stamyr, Kristin
core +1 more source
44-year-old female known case of Crohn’s disease and depression who presented with a few hours’ history of severe abdominal pain and multiple episodes of vomiting faeculant matter.
Abela, Franklin, Dimech, Anthony Pio
core +1 more source
Safe and effective prescribing with dyslexia [PDF]
Background: The term ‘dyslexia’ refers to a condition that impacts upon reading and writing abilities whilst not altering intelligence. Individuals with dyslexia may have difficulties with the speed and accuracy and their reading and writing, amongst ...
Anderson, John L+3 more
core +1 more source
Vascular Effects of the Fetal Hemoglobin Inducer Agent 3-(1,3-Dioxoisoindolin-2-yl) Benzyl Nitrate
Vascular endothelium is a protective layer of cells lining the lumen of blood vessels that plays important roles by releasing factors responsible for controlling the vascular tone, regulating the expression of pro-inflammatory cytokines, and expressing ...
Barbara Terroni+4 more
doaj +1 more source