High-Dose Hydroxocobalamin for Refractory Vasoplegia Post Cardiac Surgery
Administration of high-dose hydroxocobalamin, or vitamin B12, is an emerging, targeted rescue therapy for the treatment of refractory vasoplegic shock.
M. Bak+3 more
semanticscholar +1 more source
Vasoplegic syndrome, a possible complication of cardiopulmonary bypass, is a critical state of unregulated systemic vasodilation with decreased vascular resistance and a pathological insensitivity to conventional inotropes and vasoconstrictors. This case
Jacob Lambert+8 more
doaj +1 more source
Past, present and future of cyanide antagonism research: From the early remedies to the current therapies. [PDF]
This paper reviews milestones in antidotal therapies for cyanide (CN) spanning early remedies, current antidotal systems and research towards next generation therapies. CN has been a part of plant defense mechanisms for millions of years.
Budai, Marianna+3 more
core +2 more sources
A Case of Hydroxocobalamin-Induced False Blood Leak Alarm on Dialysis Machine
Hemodialysis machines are equipped with a blood leak detector/alarm to prevent loss of blood following rupture of semipermeable membrane; the blood leak alarms could also be triggered by sensor malfunction or presence of air bubbles in the system ...
Praveen Datar MBBS+5 more
doaj +1 more source
Early biomarker response and patient preferences to oral and intramuscular vitamin B12 substitution in primary care: a randomised parallel-group trial [PDF]
Vitamin B12 (VB12) deficiency can be treated with oral high-dose substitution or intramuscular (i.m.) injection of VB12. Whenever alternative routes of administration exist, patient preferences should be considered when choosing the treatment.
Arnet, Isabelle+5 more
core +2 more sources
Protocol Compliance Guiding Angiotensin II Use in Post Cardiovascular Surgery Vasoplegia
OBJECTIVES:. Catecholamines and vasopressin are commonly used in patients with post cardiovascular surgery vasoplegia (PCSV). Multimodal therapy, including methylene blue (MB), hydroxocobalamin, and angiotensin II (Ang II), may improve outcomes in ...
Caitlin C. ten Lohuis, MSN, ACNP-BC+5 more
doaj +1 more source
Chemical composition, vasorelaxant, antioxidant and antiplatelet effects of essential oil of Artemisia campestris L. from Oriental Morocco [PDF]
Background: Artemisia campestris L. (Asteraceae) is a medicinal herb traditionally used to treat hypertension and many other diseases. Hence, this study is aimed to analyze the essential oil of A.
Assaidi, Asmae+10 more
core +1 more source
Cyanocobalamin (CNCbl) and aquo/hydroxocobalamin (HOCbl) are the forms of vitamin B12 that are most commonly used for supplementation. They are both converted to methylcobalamin (MeCbl) and 5′-deoxyadenosylcobalamin (AdoCbl), which metabolize ...
Sergey N. Fedosov+2 more
semanticscholar +1 more source
MODERN DIAGNOSTIC AND TREATMENT OF VITAMIN В12 DEFICIENCY
An article reflects modern concepts of the etiology of vitamin B12 deficiency including medication-induced conditions. Particular attention is paid to diagnostic algorithm in case of overt and latent forms of deficit.
A. L. Krasnovskiy+5 more
doaj +1 more source
Vascular Effects of the Fetal Hemoglobin Inducer Agent 3-(1,3-Dioxoisoindolin-2-yl) Benzyl Nitrate
Vascular endothelium is a protective layer of cells lining the lumen of blood vessels that plays important roles by releasing factors responsible for controlling the vascular tone, regulating the expression of pro-inflammatory cytokines, and expressing ...
Barbara Terroni+4 more
doaj +1 more source