Results 21 to 30 of about 6,185 (138)
Phospholipids, Sphingolipids, and Cholesterol-Derived Lipid Mediators and Their Role in Neurological Disorders. [PDF]
Int J Mol SciNeural membranes are composed of phospholipids, sphingolipids, cholesterol, and proteins. In response to cell stimulation or injury, the metabolism of lipids generates various lipid mediators, which perform many cellular functions.
Farooqui AA, Farooqui T.
europepmc +2 more sources
1H. Liver X receptor-like receptors in GtoPdb v.2023.1 [PDF]
, 2023 Liver X and farnesoid X receptors (LXR and FXR, nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [76, 3]) are members of a steroid analogue-activated nuclear receptor subfamily, which form heterodimers with members of the
Rachid Safi +3 more
core +1 more source
Journal of Lipid Research, 1996 Oxidation of low density lipoprotein (LDL) in the artery wall leads to the formation of cholesterol oxidation products that may result in cytotoxicity.
R P Patel +4 more
doaj +1 more source
Journal of Lipid Research, 1997 7-Hydroperoxycholesterols (7OOHs) are intermediates in cholesterol oxidation and potential cytotoxins. A normal-phase HPLC method with UV (205 nm) detection was developed that could resolve 7 alpha OOH, 7 beta OOH, 7-ketocholesterol (7K), and the ...
A J Brown, S L Leong, R T Dean, W Jessup
doaj +1 more source
1H. Liver X receptor-like receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]
, 2019 Liver X and farnesoid X receptors (LXR and FXR, nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [68]) are members of a steroid analogue-activated nuclear receptor subfamily, which form heterodimers with members of the ...
McDonnell, Donald P., Safi, Rachid
core +1 more source
25-Hydroxycholesterol as a Signaling Molecule of the Nervous System
Biochemistry (Moscow), 2022 Cholesterol is an essential component of plasma membrane and precursor of biological active compounds, including hydroxycholesterols (HCs). HCs regulate cellular homeostasis of cholesterol; they can pass across the membrane and vascular barriers and act ...
U. G. Odnoshivkina +2 more
semanticscholar +1 more source
The Impact of Brain Cholesterol (24-hydroxycholesterol (24-HC) and 27- hydroxycholesterol (27-HC)) on Invitro Phenotypes of Brain Metastatic Breast Cancer Cells [PDF]
Introduction: Brain metastases is one of the leading causes of breast cancer mortality and rates continue to increase. It has been previously shown that cholesterol metabolism is an important regulator of cancer progression.
Iroabuchi, Cherish
core +3 more sources
Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse [PDF]
, 2014 Oxysterols are oxidised forms of cholesterol or its precursors. In this study we utilised the cholesterol 24-hydroxylase knockout mouse (Cyp46a1-/-) to study the sterol and oxysterol content of brain.
Griffiths, William J +5 more
core +1 more source
Cholesterol levels in serum, the liver, and the aorta.
, 2014 Concentrations of cholesterol, cholesteryl esters, and phytosterols are expressed in µg/mL or µg/g; concentrations of cholesterol precursors and hydroxycholesterols are expressed in ng/mL or ng/g.I, Group I; II, Group II; III, Group III; IV, Group IV; I ...
Eung Ju Kim (573340) +6 more
core +1 more source
Advanced Science, EarlyView.Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu +9 more
wiley +1 more source