Results 91 to 100 of about 5,125,991 (297)

Generation of Pseudo Metabolites as a Side Reaction in On‐Tissue Chemical Derivatization in Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Chemistry–Methods, Volume 5, Issue 12, November 2025.
On‐tissue chemical derivatization reagents enhance sensitivity and specificity, but the impact of side reactions remains understudied. The reactive matrix FMP‐10 promotes Mukaiyama‐like condensation reactions between endogenous metabolites to form pseudo metabolites that are structurally identical to endogenous metabolites.
Tobias Bausbacher, Alessa L. Henneberg, Stephanie Meyer, Stefan Schmidt, Aubry K. Miller, Christiane A. Opitz, Carsten Hopf   +6 more
wiley   +1 more source

COSMOS 2044. Experiment K-7-19. Pineal physiology in microgravity: Relation to rat gonadal function [PDF]

It is now known that the pineal organ can interact with many endocrine and nonendocrine tissues in a regulatory fashion. Given its key role in the regulation of melatonin synthesis, its high concentration, and that its levels may persist longer than the ...
Asadi, H., Holley, D., Krasnov, I., Soliman, M. R. I.   +3 more
core   +1 more source

Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Gege Li, Fangfang Li, Yang Tang, Siyu Guo, Yihan Yao, Yuan Fang, Bicheng Zhang, Yu Jiang, Jing Wang, Dang Wu, Jianxia Cheng, Zhihui Huang, Zengfeng Xin, Ting Zhang   +13 more
wiley   +1 more source

Emergence time and skin melanin spot patterns do not correlate with growth performance, social competitive ability or stress response in farmed rainbow trout [PDF]

, 2017
In wild salmonid fish, specific individual behavioral traits have been correlated with the timing of fry emergence from their gravel spawning nests; Early emerging fish display more aggressive behavior and have a higher probability of becoming socially ...
Gesto, Manuel, Jokumsen, Alfred, Skov, Peter Vilhelm   +2 more
core   +2 more sources

Tryptophan derivatives as non‐invasive diagnostic indicators for obesity‐related MASLD in children and adolescents

Diabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 7544-7560, December 2025.
Abstract Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) represents a major health burden in children and adolescents with obesity. This study aimed to characterize metabolic alterations associated with obesity‐related MASLD and to evaluate the potential of tryptophan (TRP)‐derived metabolites as non‐invasive biomarkers for early ...
Shumin Zhan, Xingyun Wang, Chen Wang, Bowen Zhu, Jianfang Gao, Zhou Peng, Rui Wang, Yun Yang, Liang Zhang, Tengfei Wang, Jiaoxiang Wu, Wei Wu, Ke Huang, Guanping Dong, Qiannan Ren, Shan Wang, Senjie Wang, Xuelian Zhou, Liling Xu, Junfen Fu, Xirong Guo   +20 more
wiley   +1 more source

The Influence of Dietary Synbiotic on Agonistic Behavior, Stress, and Brain Monoamines via Modulation of the Microbiota–Gut–Brain Axis in Laying Hens

Poultry
A complex system of neural pathways, collectively known as the microbiota–gut–brain (MGB) axis, interconnects the gut microbiota, the gastrointestinal system, and the brain along with its periphery.
Alexa M. Johnson, Alexis Clark, Mallory G. Anderson, Elyse Corbin, Mireille Arguelles-Ramos, Ahmed B. A. Ali   +5 more
doaj   +1 more source

Maternal Obesity in Pregnancy: Risk Factor for Neurodevelopmental Outcomes in Offspring

Journal of Neurochemistry, Volume 169, Issue 12, December 2025.
Maternal obesity during pregnancy induces metabolic and inflammatory disturbances that alter the offspring brain environment, characterized by neuroinflammation, glial activation, disrupted neurotransmitter signaling, and mitochondrial and synaptic dysfunction, ultimately increasing the risk of adverse neurodevelopmental outcomes, with persistent ...
Luisa O. Schmitt, Giuseppe Faraco, Tamires S. Stivanin, Joana M. Gaspar   +3 more
wiley   +1 more source

Catha edulis chewing effects on treatment of paranoid schizophrenic patients

Neuropsychiatric Disease and Treatment, 2015
Mohamed-I Kotb El-Sayed, Hatem-K Amin Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Ain Helwan, Helwan, Cairo, Egypt Background: The current study’s aim is to evaluate the possible interaction ...
Kotb El-Sayed MI, Amin HK
doaj  

Changes in Striatal N-methyl-D-aspartate (NMDA) Stimulation of Dopamine Release and Receptor Subunit Expression During Expression of and Recovery from MPTP-Induced Parkinsonism [PDF]

, 2001
Normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated cats were used to examine changes in N-methyl-D-aspartate (NMDA) receptor function.
Desai, Dr. Anup, Rothblat, Dr. David, Schneider, Dr. Jay   +2 more
core  

Comparison Among Aerobic Exercise and Other Types of Interventions to Treat Depression: A Systematic Review [PDF]

, 2015
Depression is a common and disabling disease that affects over 100 million people worldwide and can have a significant impact on physical and mental health, reducing their quality of life.
Arias-Carrión, Oscar, Budde, Henning, de Souza Moura, Antonio Marcos, de Sá Filho, Alberto Souza, Lamego, Murilo Khede, Machado, Sergio, Manochio, João, Mura, Gioia, Nardi, Antonio Egidio, Paes, Flávia, Rimes, Ridson, Rocha, Nuno, Rocha, Susana, Simoes-Silva, Vitor, Wegner, Mirko, Yuan, Ti-Fei   +15 more
core   +1 more source