Results 151 to 160 of about 148,924 (212)
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Cold Spring Harbor Protocols, 2007
INTRODUCTIONThe hydroxyl-radical footprinting methodology has wide applications to studying protein-DNA interactions, as well as structural perturbations (e.g., bending) that occur in DNA during protein binding. Hydroxyl radicals cleave DNA by abstracting a hydrogen atom from C4 of the sugar in the minor groove.
Michael, Carey, Stephen T, Smale
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INTRODUCTIONThe hydroxyl-radical footprinting methodology has wide applications to studying protein-DNA interactions, as well as structural perturbations (e.g., bending) that occur in DNA during protein binding. Hydroxyl radicals cleave DNA by abstracting a hydrogen atom from C4 of the sugar in the minor groove.
Michael, Carey, Stephen T, Smale
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Analytical Biochemistry, 1981
Abstract A mixture of xanthine or hypoxanthine and xanthine oxidase generates the superoxide radical, O2 • , and H2O2. In the presence of iron salts, O2 • and H2O2 can interact to produce the hydroxyl radical, OH·. Superoxide-dependent formation of OH· can be measured by its ability to hydroxylate salicylate as followed by an improved ...
R, Richmond +3 more
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Abstract A mixture of xanthine or hypoxanthine and xanthine oxidase generates the superoxide radical, O2 • , and H2O2. In the presence of iron salts, O2 • and H2O2 can interact to produce the hydroxyl radical, OH·. Superoxide-dependent formation of OH· can be measured by its ability to hydroxylate salicylate as followed by an improved ...
R, Richmond +3 more
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Optimizing electron spin resonance detection of hydroxyl radical in water
Chemosphere, 2003 The parameters affecting the electron spin resonance (ESR) detection of hydroxyl free radical in water are studied and optimized. The hydroxyl radical is generated by the Fenton reaction with iron (II) ammonium sulfate and hydrogen peroxide reacting in a
Kwong-Yu Chan
exaly +2 more sources
The Benzylperoxyl Radical as a Source of Hydroxyl and Phenyl Radicals
Chemistry – A European Journal, 2014AbstractThe benzyl radical (1) is a key intermediate in the combustion and tropospheric oxidation of toluene. Because of its relevance, the reaction of 1 with molecular oxygen was investigated by matrix‐isolation IR and EPR spectroscopy as well as computational methods.
Sander, Wolfram +4 more
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Scavenging of hydroxyl radical by catecholamines
Luminescence, 2012ABSTRACTThe direct effects of the four catecholamines (CATs), adrenaline (A), noradrenaline (NA), dopamine (D) and isoproterenol (I), on free radicals were investigated using the free radical 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH•) and hydroxyl radial (HO•).
Aleksandra, Kładna +4 more
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The Reaction of Acetylene with Hydroxyl Radicals
The Journal of Physical Chemistry A, 2005The potential energy surface for the reaction between OH and acetylene has been calculated using the RQCISD(T) method and extrapolated to the complete basis-set limit. Rate coefficients were determined for a wide range of temperatures and pressures, based on this surface and the solution of the one-dimensional and two-dimensional master equations. With
Juan P, Senosiain +2 more
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Hydroxyl Radical Reactivity with Diethylhydroxylamine
Science, 1977Diethylhydroxylamine (DEHA) reacts with gas-phase hydroxyl radicals on every third collision, whereas the corresponding reaction in aqueous solution is considerably slower. The high gas-phase reactivity explains the predicted inhibitory effect of DEHA in atmospheric smog processes. Results from the studies in the aqueous phase are helpful in predicting
R A, Gorse, R R, Lii, B B, Saunders
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Reaction of dipyridamole with the hydroxyl radical
Lipids, 1992AbstractDipyridamole [2,6‐bis‐diethanolamino‐4,8‐dipiperidinopyrimido‐(5,4‐d) pyrimidine], a well known platelet aggregation inhibitor, shows powerful hydroxyl radical scavenging activity by inhibiting OH‐dependent salicylate and deoxyribose degradation.
IULIANO, Luigi +4 more
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Hydroxyl radical formation by dithranol
Biochemical Pharmacology, 1988Ethene formation from 2-keto-thiomethyl-butyric acid (KMBA) was used to measure hydroxyl radical generation from the antipsoriatic drug dithranol in phosphate buffer pH 7.8. Because the singlet oxygen (1O2) sensitizer, rose bengale, showed enlarged production of ethene when irradiated in the presence of KMBA, experiments were performed in the dark in ...
K, Müller, H, Kappus
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The detection of hydroxyl radicals in vivo
Journal of Inorganic Biochemistry, 2008Several indirect methods have been developed for the detection and quantification of highly reactive oxygen species (hROS), which may exist either as free hydroxyl radicals, bound "crypto" radicals or Fe(IV)-oxo species, in vivo. This review discusses the strengths and weaknesses associated with those most commonly used, which determine the ...
W. Freinbichler +6 more
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