Results 301 to 310 of about 278,689 (355)
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Thiol-induced hydroxyl radical formation and scavenger effect of thiocarbamides on hydroxyl radicals
Journal of Inorganic Biochemistry, 1986The effects of thiols and thiocarbamides on hydroxyl radical (.OH) formation by the hypoxanthine(HYP)-xanthine oxidase(XOD)-Fe3+ .EDTA system were investigated in the range of 0.5-5 mM by colorimetrically measuring salicylate hydroxylation. Thiocarbamides powerfully inhibited the hydroxylation while thiols showed a paradoxical effect, enhancing it at ...
N, Motohashi, I, Mori
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Effective Inhibition of Hydroxyl Radicals by Hydroxylated Biphenyl Compounds
Free Radical Research Communications, 1993In aqueous media, approximate rate constants for the reactions between hydroxyl radicals (.OH) and biphenyl compounds such as dehydrodieugenol, magnolol, honokiol, dehydrodidihydroeugenol, dehydrodivanillyl alcohol, and dehydrodicreosol were estimated by competition reactions for .OH between these biphenyls and 5,5-dimethyl-1-pyrroline-N-oxide (DMPO ...
J, Taira +5 more
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DNA footprinting with hydroxyl radical
Nature, 1988High resolution images of proteins bound to DNA can be achieved through the use of a simple inorganic chemical system that produces the hydroxyl radical.
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Addition Radicals Formed by Hydroxyl Radical Bombardment of Uracil
Science, 1966Direct addition of O—H radicals at room temperature to the carbon No. 5 of the uracil ring has been proved by measurement of the proton hyperfine structure in the electron spin resonance of the resulting uracil + O—H radicals. Upon addition of the OH, the H originally bound to carbon No. 5 shifts to No. 6, thus forming a methylene group at carbon No. 6,
Herak, Janko, Gordy, Walter
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Analytical Biochemistry, 2001
Hydroxylation of l-phenylalanine (Phe) by hydroxyl radical (*OH) yields 4-, 3-, and 2-hydroxyl-Phe (para-, meta-, and ortho-tyrosine, respectively). Phe derivative measurements have been employed to detect *OH formation in cells and tissues, however, the specificity of this assay is limited since Phe derivatives also arise from intracellular Phe ...
BIONDI, Roberto +5 more
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Hydroxylation of l-phenylalanine (Phe) by hydroxyl radical (*OH) yields 4-, 3-, and 2-hydroxyl-Phe (para-, meta-, and ortho-tyrosine, respectively). Phe derivative measurements have been employed to detect *OH formation in cells and tissues, however, the specificity of this assay is limited since Phe derivatives also arise from intracellular Phe ...
BIONDI, Roberto +5 more
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Glycol Splitting by Hydroxyl Radicals
Nature, 1946RECENTLY1 I suggested, on theoretical grounds, that the splitting of I±-glycols to aldehydes or ketones by means of lead tetra-acetate was due to dehydrogenation by free acetate radicals.
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Estrogen diminishes postischemic hydroxyl radical production
American Journal of Physiology-Heart and Circulatory Physiology, 1998Reperfusion of blood flow to an ischemic myocardium is imperative to survival; ironically, it may also manifest several pathophysiological conditions. The most important of these are reperfusion arrhythmias and tissue injury and/or death. The mechanisms involved in reperfusion arrhythmias remain to be fully elucidated; however, increasing evidence ...
N A, McHugh, G F, Merrill, S R, Powell
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2000
Abstract Hydroxyl radicals have now been used for more than 15years to probe the structure of various macromolecules. They have also been widely used to footprint DNA-protein and RNA-protein complexes (1, 2). Hydroxyl radicals are w1y small, comparable in size to a water molecule, are most commonly generated from FeEDTA in solution by
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Abstract Hydroxyl radicals have now been used for more than 15years to probe the structure of various macromolecules. They have also been widely used to footprint DNA-protein and RNA-protein complexes (1, 2). Hydroxyl radicals are w1y small, comparable in size to a water molecule, are most commonly generated from FeEDTA in solution by
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Hydroxyl radical-scavenging property of indomethacin
Molecular and Cellular Biochemistry, 1994The ability of indomethacin to scavenge hydroxyl radical (.OH) using high pressure liquid chromatography (HPLC) was investigated. .OH radical was generated by photolysis of H2O2 (1.5-10 mmoles/L) with UV light and was trapped with salicyclic acid (500 nmoles). H2O2 produced .OH in a concentration-dependent manner as estimated by .OH adduct products 2,3-
K, Prasad, V A, Laxdal
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Scavenging of hydroxyl radical by catecholamines
Luminescence, 2012ABSTRACTThe direct effects of the four catecholamines (CATs), adrenaline (A), noradrenaline (NA), dopamine (D) and isoproterenol (I), on free radicals were investigated using the free radical 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH•) and hydroxyl radial (HO•).
Aleksandra, Kładna +4 more
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