Results 101 to 110 of about 111,305 (353)

The in vitro enzymic hydroxylation of steroid hormones. 2. Enzymic 11β-hydroxylation of progesterone by ox-adrenocortical mitochondria [PDF]

, 1954
Alexander C. Brownie, J. K. Grant, D. W. Davidson   +2 more
openalex   +1 more source

A Machine Learning Perspective on the Brønsted–Evans–Polanyi Relation in Water‐Gas Shift Catalysis on MXenes

Advanced Intelligent Discovery, EarlyView.
Machine learning predicts activation energies for key steps in the water‐gas shift reaction on 92 MXenes. Random Forest is identified as the most accurate model. Reaction energy and reactant LogP emerge as key descriptors. The approach provides a predictive framework for catalyst design, grounded in density functional theory data and validated through ...
Kais Iben Nassar, Tiago L. P. Galvão, José D. Gouveia, José R. B. Gomes   +3 more
wiley   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

Advanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki, Bassam Bachour Junior, Marcelo Mulato, José Ilton de Oliveira Filho   +3 more
wiley   +1 more source

Active site diversification of P450cam with indole generates catalysts for benzylic oxidation reactions

Beilstein Journal of Organic Chemistry, 2015
Cytochrome P450 monooxygenases are useful biocatalysts for C–H activation, and there is a need to expand the range of these enzymes beyond what is naturally available.
Paul P. Kelly, Anja Eichler, Susanne Herter, David C. Kranz, Nicholas J. Turner, Sabine L. Flitsch   +5 more
doaj   +1 more source

Chiral phase-transfer catalysis in the asymmetric α-heterofunctionalization of prochiral nucleophiles

Beilstein Journal of Organic Chemistry, 2017
Chiral phase-transfer catalysis is one of the major catalytic principles in asymmetric catalysis. A broad variety of different catalysts and their use for challenging applications have been reported over the last decades.
Johannes Schörgenhumer, Maximilian Tiffner, Mario Waser   +2 more
doaj   +1 more source

Direct Enzymatic Route for the Preparation of Novel Enantiomerically Enriched Hydroxylated β-Amino Ester Stereoisomers

Molecules, 2010
Enantiomerically enriched hydroxy-substituted b-amino esters have been synthesized through CAL-B-catalyzed enantioselective hydrolysis in organic media.
Enikő Forró, László Schönstein, Loránd Kiss, Alberto Vega-Peñaloza, Eusebio Juaristi, Ferenc Fülöp   +5 more
doaj   +1 more source

P4HA1 is a new regulator of the HIF-1 pathway in breast cancer

Cell Stress, 2019
Hypoxia-Inducible Factor (HIF)-1 is a transcription factor that plays the key role in response to low oxygen concentrations, or hypoxia. Activation of the HIF-1 pathway is not only crucial for normal tissue development and function, but also involved in ...
Ren Xu
doaj   +1 more source

In vivo evaluation of cholesterol 7 alpha-hydroxylation in humans: effect of disease and drug treatment.

Journal of Lipid Research, 1990
7 alpha-Hydroxylation of cholesterol is a stereospecific reaction consisting of the replacement of the 7 alpha-hydrogen with a hydroxyl group. When cholesterol labeled with tritium at the 7 alpha position is administered, the hydroxylation of the ...
M Bertolotti, N Carulli, D Menozzi, F Zironi, A Digrisolo, A Pinetti, M G Baldini   +6 more
doaj  

Hydroxylation of Furan with Osmium Tetroxide. [PDF]

, 1947
Niels Clauson-Kaas, Jørgen Fakstorp, Hilkka Linkola, Annikki Linnasalmi, Pentti Laukkanen   +4 more
openalex   +1 more source

Fungal-Mediated Biotransformation of the Plant Growth Regulator Forchlorfenuron by Cunninghamella elegans

Metabolites
The synthetic cytokinin forchlorfenuron (FCF), while seemingly presenting relatively low toxicity for mammalian organisms, has been the subject of renewed scrutiny in the past few years due to its increasing use in fruit crops and potential for ...
Charles M. Moreno, Jaclyn N. Moreno, Matthew C. Valdez, Melinda P. Baldwin, Ana C. Vallor, Paulo B. Carvalho   +5 more
doaj   +1 more source