Results 101 to 110 of about 194,006 (386)
Advanced Healthcare Materials, EarlyView.A soft, stretchable, anti‐biofouling encapsulant is developed by integrating organosilicon nanowire networks with microstructured biodegradable elastomers. The hierarchical surface exhibits superhydrophobicity and enhances water barrier properties by 420% over pristine polymers, while preserving mechanical integrity.
Won Bae Han +7 more
wiley +1 more source
Cezanne regulates E2F1-dependent HIF2α expression [PDF]
, 2015 Mechanisms regulating protein degradation ensure the correct and timely expression of transcription factors such as hypoxia inducible factor (HIF).
Altun +48 more
core +4 more sources
Stabilizing Frustrated Phase Transitions in Selective Oxidation Reactions
Advanced Materials, EarlyView.Using multimodal operando spectromicroscopy, the frustrated phase transition responsible for selective oxidation over cobalt oxide spinel catalysts is identified, corresponding to combined surface reaction and Mars‐van Krevelen (MvK) dynamics. This regime is disrupted by the formation of mobile vacancies and the depletion of active oxygen at high ...
Luis Sandoval‐Diaz +11 more
wiley +1 more source
FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1
PLoS Biology, 2016 The asparagine hydroxylase, factor inhibiting HIF (FIH), confers oxygen-dependence upon the hypoxia-inducible factor (HIF), a master regulator of the cellular adaptive response to hypoxia.
Carsten C. Scholz +15 more
semanticscholar +1 more source
Experimental realization of catalytic CH_4 hydroxylation predicted for an iridium NNC pincer complex, demonstrating thermal, protic, and oxidant stability [PDF]
, 2009 A discrete, air, protic, and thermally stable (NNC)Ir(III) pincer complex was synthesized that catalytically activates the CH bond of methane in trifluoroacetic acid; functionalization using NaIO_4 and KIO_3 gives the oxy ...
Ess, Daniel H. +6 more
core +1 more source
In vivo effect of dried chicory root (Cichorium intybus L.) on xenobiotica metabolising cytochrome P450 enzymes in porcine liver [PDF]
, 2011 Cytochrome P450 (CYP) enzymes are widely studied for their involvement in metabolism of drugs and endogenous compounds. In porcine liver, CYP1A2,2Aand 2E1 are important for the metabolism of skatole.Feeding chicory roots to pigs is known to decrease the ...
Ekstrand, Bo +2 more
core +1 more source
An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels +7 more
wiley +1 more source
On the heterogeneity of the mitochondrial C27-steroid 26-hydroxylase system
Journal of Lipid Research, 1976 Mitochondrial 26-hydroxylation of exogenous cholesterol, endogenous cholesterol, and 5β-cholestane-3α,7α,12α-triol was studied. 26-Hydroxylation of endogenous cholesterol was measured by mass fragmentography.
J Gustafsson
doaj +1 more source
Molecular & Cellular Oncology, 2020 Hydroxylation is a post-translational modification affecting protein stability, activity or interactome. We identified adenylosuccinate lyase (ADSL) as a novel hydroxylation substrate in triple negative breast cancer. Hydroxylation affects ADSL enzymatic
Giada Zurlo, Qing Zhang
doaj +1 more source
Directing group assisted meta-hydroxylation by C–H activation
Chemical Science, 2016 The first template assisted meta-hydroxylation strategy and its use in the synthesis of resveratrol precursor and QR-activity inducer with detailed experimental and in-silico mechanistic understanding.
Arun Maji +4 more
semanticscholar +1 more source