Results 91 to 100 of about 13,094 (219)

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Effects of short-term atorvastatin use in patients with calcium stones: A randomized placebo-controlled clinical trial [PDF]

Investigative and Clinical Urology, 2019
Purpose: A few experimental and observational studies have reported that atorvastatin prevents calcium oxalate stone formation. Our study is the first to investigate the effect of atorvastatin on 24-hour urinary metabolites, urinary malondialdehyde (U ...
Fatemeh Taheri, Maryam Taheri, Abbas Basiri, Alireza Khoshdel, Fariba Samadian, Sanaz Tavasoli   +5 more
doaj   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

Journal of the American Geriatrics Society, Volume 73, Issue 12, Page 3679-3689, December 2025.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao, Yuxuan Zhao, Xiaowen Hu, Xue Wang, Gengchen Wang, Xinyi Zhang, Wenliang Dong, Luwen Shi, Xiaodong Guan, Christine Y. Lu, Pengfei Jin, Xiaoyan Nie   +11 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2015/16:Enzymes [PDF]

, 2015
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org),
Aldrich, R, Alexander, SPH, Attali, B, Back, M, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Benson, HE, Biel, M, Birdsall, NJ, Boison, D, Brauner-Osborne, H, Broeer, S, Bryant, C, Burnstock, G, Burris, T, Cain, D, Calo, G, Chan, SL, Chandy, KG, Chiang, N, Christakos, S, Christopoulos, A, Chun, JJ, Chung, J-J, Clapham, DE, Connor, MA, Coons, L, Cox, HM, Dautzenberg, FM, Davies, JA, Dent, G, Douglas, SD, Dubocovich, ML, Edwards, DP, Fabbro, D, Faccenda, E, Farndale, R, Fong, TM, Forrest, D, Fowler, CJ, Fuller, P, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, SAN, Grimm, SL, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hammond, JR, Hancox, JC, Hartig, S, Hauger, RL, Hay, DL, Hebert, T, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, GE, Jensen, R, Jetten, A, Jockers, R, Kaczmarek, LK, Kanai, Y, Kang, HS, Karnik, S, Kelly, E, Kerr, ID, Korach, KS, Lange, CA, Larhammar, D, Leeb-Lundberg, F, Leurs, R, Lolait, SJ, Macewan, D, Maguire, JJ, Marrion, N, May, JM, Mazella, J, McArdle, CA, McDonnell, DP, Michel, MC, Miller, LJ, Mitolo, V, Monie, T, Monk, PN, Mouillac, B, Murphy, PM, Nahon, J-L, Nerbonne, J, Nichols, CG, Norel, X, Oakley, R, Offermanns, S, Palmer, LG, Panaro, MA, Pawson, AJ, Perez-Reyes, E, Pertwee, RG, Peters, JA, Pike, JW, Pin, JP, Pintor, S, Plant, LD, Poyner, DR, Prossnitz, ER, Pyne, S, Ren, D, Richer, JK, Rondard, P, Ross, RA, Sackin, H, Safi, R, Sanguinetti, MC, Sartorius, CA, Segaloff, DL, Sharman, JL, Sladek, FM, Southan, C, Stewart, G, Stoddart, LA, Striessnig, J, Summers, RJ, Takeda, Y, Tetel, M, Toll, L, Trimmer, JS, Tsai, M-J, Tsai, SY, Tucker, S, Usdin, TB, Vilargada, J-P, Vore, M, Ward, DT, Waxman, SG, Webb, P, Wei, AD, Weigel, N, Willars, GB, Winrow, C, Wong, SS, Wulff, H, Ye, RD, Young, M, Zajac, J-M   +151 more
core   +4 more sources

The Carba Mix—In Vitro Investigations of Potential Cocktail Effects in Patch Tests With Rubber Allergens

Contact Dermatitis, Volume 93, Issue 4, Page 316-327, October 2025.
The carba mix was studied in a human cell model to better understand human patch reactions to the mix. Our results support that the carba mix can give rise to cocktail effect and that patch testing with separate carba mix sensitisers may thus be more appropriate.
Linda Ljungberg Silic, Renato Ivan de Ávila, Sofía Carreira‐Santos, Gábor Merényi, Ola Bergendorff, Kathrin S. Zeller   +5 more
wiley   +1 more source

Urine Complement Proteins and the Risk of Kidney Disease Progression and Mortality in Type 2 Diabetes. [PDF]

, 2018
ObjectiveWe examined the association of urine complement proteins with progression to end-stage renal disease (ESRD) or death in people with type 2 diabetes and proteinuric diabetic kidney disease (DKD).Research design and methodsUsing targeted mass ...
Afkarian, Maryam, Babenko, Ilona, Durbin-Johnson, Blythe, Mehrotra, Rajnish, Rocke, David M, Vaisar, Tomas, Whitlock, Kathryn   +6 more
core   +1 more source

Age-associated alterations in cholesterol homeostasis: evidence from a cross-sectional study in a Northern Italy population. [PDF]

, 2014
BACKGROUND: The modifications of cholesterol metabolism associated with aging are ill-defined. The objective of this study was to define age-associated alterations of the different metabolic pathways controlling cholesterol homeostasis by analyzing ...
Anzivino C, BALDELLI, Enrica, BERTOLOTTI, Marco, Carulli N., CARULLI, Lucia, Del Puppo M, LORIA, Paola, Magni A, MUSSI, Chiara, OGNIBENE, Silvia, Pellegrini E   +10 more
core   +1 more source

Secondary Dyslipidemia In Obese Children - Is There Evidence For Pharmacological Treatment?

Arquivos Brasileiros de Cardiologia, 2018
Background: Long-term safety, effectiveness and criteria for treatment with statins in children are still unclear in clinical practice. There is very limited evidence for the use of medication to treat children with dyslipidemia secondary to obesity who ...
Graciane Radaelli, Grasiele Sausen, Claudia Ciceri Cesa, Vera Lucia Portal, Lucia Campos Pellanda   +4 more
doaj   +1 more source

Gut Microbiota‐Derived Metabolites Orchestrate Metabolic Reprogramming in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Frontiers

The FASEB Journal, Volume 39, Issue 17, 15 September 2025.
Schematic representation of how gut microbiota‐derived metabolites—such as SCFAs, TMAO, and tryptophan derivatives—modulate cardiac energy metabolism, inflammation, and epigenetic regulation, contributing to the pathogenesis of diabetic cardiomyopathy. Therapeutic strategies targeting the gut–heart axis hold translational promise for metabolic cardiac ...
Jing‐yu Jin, Xin‐yu Yang, Ru Feng, Meng‐liang Ye, Hui Xu, Jing‐yue Wang, Jia‐chun Hu, Heng‐tong Zuo, Jin‐yue Lu, Jian‐ye Song, Yi Zhao, Yan Wang, Qian Tong   +12 more
wiley   +1 more source

Effects of exercise on the cognition of older women treated with lovastatin

Biomédica: revista del Instituto Nacional de Salud, 2018
Introduction: The deterioration of cognition is highly predominant in older adults. Objective: The aim of this study was to analyze the effects of a walking program on the cognition and blood concentration of lipids in women over 60 years of age who were
Edgardo Molina-Sotomayor, Rocío Arreguín-Moreno, Fernando Rodríguez-Rodríguez, Francisco Pradas, Juan Antonio León, José Antonio González-Jurado   +5 more
doaj   +1 more source