Molecular actions of hypocholesterolaemic compounds from edible mushrooms [PDF]
, 2018 Cholesterol levels are strictly regulated to maintain its homeostasis; therefore, if it is not absorbed with the diet, the cholesterol biosynthetic pathway is enhanced and vice versa.
Gil-Ramírez, Alicia +2 more
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Effects of statin use on serum creatinine phosphokinase levels in normal thyroid function [PDF]
The Korean Journal of Internal MedicineBackground/Aims Statins are common lipid-lowering agents used in dyslipidemia. However, they increase serum creatinine phosphokinase (CPK) levels. Currently, there are no studies on the effect of thyroid-stimulating hormone (TSH) levels on CPK levels ...
Jeonghoon Ha +7 more
doaj +1 more source
HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypass. [PDF]
, 2015 BACKGROUND: Acute kidney injury (AKI) is common in patients undergoing cardiac surgery among whom it is associated with poor outcomes, prolonged hospital stays and increased mortality.
Lewicki, M., Ng, I., Schneider, A.G.
core +1 more source
Statin-associated necrotizing myopathy: a rare etiology
Revista Portuguesa de Medicina Geral e Familiar, 2020 Introduction: Necrotizing autoimmune myopathy is a rare entity characterized by proximal muscle weakness, elevated creatine kinase levels, potential autoantibody presence, and myofiber necrosis with reduced or absent inflammation.
Catarina Ferreira Moita +4 more
doaj +1 more source
Statins and protein prenylation in cancer cell biology and therapy [PDF]
, 2012 El pdf del artículo es la versión post-print.The use of statins has scaled up to become one of the most prescribed medicines in the world and have been very useful in the manegement of cardiovascular diseases and related mortality.
Fernández-Checa, José C. +2 more
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Association between statins administration and glaucoma; a systematic review and meta-analysis of observational studies [PDF]
Journal of NephropharmacologyIntroduction: Glaucoma is the leading cause of irreversible visual impairment in the world. Statins, primarily through their lipid-lowering effects, have been suggested to play a potential role in influencing the incidence of glaucoma. Consequently, this
Moloud Fakhri +3 more
doaj +1 more source
Clustering cliques for graph-based summarization of the biomedical research literature [PDF]
, 2013 BACKGROUND: Graph-based notions are increasingly used in biomedical data mining and knowledge discovery tasks. In this paper, we present a clique-clustering method to automatically summarize graphs of semantic predications produced from PubMed citations (
A Naud +53 more
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MTD–CoMSIA modelling of HMG-CoA reductase inhibitors [PDF]
Journal of the Serbian Chemical Society, 2011 The 3D quantitative structure–activity relationship for a series of hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors based on the pyrrolylethyl-tetrahydropyranone scaffold was examined using the Minimal Topological Difference (MTD) method and ...
DANIEL M. DUDA-SEIMAN +6 more
doaj
C-reactive protein in aortic valve disease [PDF]
, 2006 Aortic Valve Disease, includes a range of disorder severity from mild leaflet thickening without valve obstruction, "aortic sclerosis", to severe calcified aortic stenosis.
Pedro L Sanchez, Anna Maria Mazzone
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Reduction of Brain β-Amyloid (Aβ) by Fluvastatin, a Hydroxymethylglutaryl-CoA Reductase Inhibitor, through Increase in Degradation of Amyloid Precursor Protein C-terminal Fragments (APP-CTFs) and Aβ Clearance [PDF]
Journal of Biological Chemistry, 2010 Epidemiological studies suggest that statins (hydroxymethylglutaryl-CoA reductase inhibitors) could reduce the risk of Alzheimer disease. Although one possible explanation is through an effect on beta-amyloid (Abeta) metabolism, its effect remains to be elucidated.
Mitsuru, Shinohara +9 more
openaire +2 more sources