Recent advances: rheumatology [PDF]
, 2000 No abstract ...
Madhok, R., Kerr, H., Capell, H.A.
core +6 more sources
Effects of statin use on serum creatinine phosphokinase levels in normal thyroid function [PDF]
The Korean Journal of Internal MedicineBackground/Aims Statins are common lipid-lowering agents used in dyslipidemia. However, they increase serum creatinine phosphokinase (CPK) levels. Currently, there are no studies on the effect of thyroid-stimulating hormone (TSH) levels on CPK levels ...
Jeonghoon Ha +7 more
doaj +1 more source
Statin-associated necrotizing myopathy: a rare etiology
Revista Portuguesa de Medicina Geral e Familiar, 2020 Introduction: Necrotizing autoimmune myopathy is a rare entity characterized by proximal muscle weakness, elevated creatine kinase levels, potential autoantibody presence, and myofiber necrosis with reduced or absent inflammation.
Catarina Ferreira Moita +4 more
doaj +1 more source
Statins and protein prenylation in cancer cell biology and therapy [PDF]
, 2012 El pdf del artículo es la versión post-print.The use of statins has scaled up to become one of the most prescribed medicines in the world and have been very useful in the manegement of cardiovascular diseases and related mortality.
Fernández-Checa, José C. +2 more
core +2 more sources
Rethinking Statin Dosage in Coronary Disease. [PDF]
Pharmacol Res PerspectIt is widely acknowledged that a sufficient statin dose is important in the management of symptomatic coronary disease, along with weight reduction and appropriate antithrombotic, blood pressure, and diabetes pharmacotherapy. Mid‐range statin doses have been shown to achieve the maximum improvements in total mortality and have the advantage of greater ...
Dimmitt SB +3 more
europepmc +2 more sources
Involvement of Rho-associated protein kinase (ROCK) and bone morphogenetic protein-binding endothelial cell precursor-derived regulator (BMPER) in high glucose-increased alkaline phosphatase expression and activity in human coronary artery smooth muscle cells [PDF]
, 2015 BACKGROUND: Vascular calcification is an independent risk factor for cardiovascular disease. Diabetes mellitus increases the incidence of vascular calcification; however, detailed molecular mechanisms of vascular calcification in diabetes mellitus remain
Ken-ichi Hirata +3 more
core +2 more sources
MTD–CoMSIA modelling of HMG-CoA reductase inhibitors [PDF]
Journal of the Serbian Chemical Society, 2011 The 3D quantitative structure–activity relationship for a series of hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors based on the pyrrolylethyl-tetrahydropyranone scaffold was examined using the Minimal Topological Difference (MTD) method and ...
DANIEL M. DUDA-SEIMAN +6 more
doaj
A systematic review and meta-analysis of the effect of statins on osteoporotic fractures [PDF]
Journal of NephropharmacologyIntroduction: Statins can increase bone density and improve osteoporosis. As fractures are the worst outcome of osteoporosis, our study aimed to investigate the relationship between statins and osteoporotic fractures using a systematic review and meta ...
Shahin Asgari-Savadjani +2 more
doaj +1 more source
Effectiveness of statin treatment for recurrent stroke according to stroke subtypes [PDF]
Journal of Medicine and Life ScienceUnderstanding the effectiveness of statin treatment is essential for developing tailored stroke prevention strategies. We aimed to evaluate the efficacy of statin treatment in preventing recurrent stroke among patients with various ischemic stroke ...
Min-Surk Kye +15 more
doaj +1 more source
Effects of Statin Use for Primary Prevention among Adults Aged 75 Years and Older in the National Health Insurance Service Senior Cohort (2002–2015) [PDF]
Annals of Geriatric Medicine and Research, 2020 Background This study aimed to identify adverse events and mortality in adults aged 75 years and older who were initially prescribed statins for primary prevention.
Sunyoung Kim +2 more
doaj +1 more source