Results 61 to 70 of about 13,094 (219)
BMC Gastroenterology, 2012 Background The aetiology of colorectal cancer (CRC) remains elusive in the majority of cases. There is experimental evidence to show that HMG-CoA reductase inhibitors (statins) may inhibit proliferation and induce cause apoptosis in CRC cells and ...
Broughton Thomas +2 more
doaj +1 more source
Evaluating an implementation strategy in cardiovascular prevention to improve prescribing of statins in Germany: an intention to treat analysis [PDF]
, 2013 BACKGROUND: The prescription of statins is an evidence-based treatment to reduce the risk of cardiovascular events in patients with elevated cardiovascular risk or with a cardiovascular disorder (CVD).
Baum, Erika +7 more
core +1 more source
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Microalgae are a highly diverse group of unicellular organisms that grow in a wide range of aquatic environments and are widely used as dietary supplements for both human and animal applications. Microalgae are rich in lipids, proteins, carbohydrates and other valuable bioactive components such as pigments, antioxidants and vitamins.
Sietse Jan Koopmans +4 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2020 INTRODUCTION: In the genesis of coronavirus disease (COVID-19), there is a process of endotheliitis associated with thrombotic changes, no studies have reported the use of acetylsalicylic acid (ASA) as a possible therapeutic approach.
Francisco Kleyton Zacarias Florêncio +3 more
doaj +1 more source
Influence of statin use on clinicopathological characteristics of localized prostate cancer and outcomes obtained after radical prostatectomy: a single center study [PDF]
, 2015 To assess the impact of statin use on biochemical recurrence (BCR) of prostate cancer after radical prostatectomy (RP)
Cattarino, Susanna +8 more
core
Isoprenoid biosynthesis in the erythrocytic stages of Plasmodium falciparum [PDF]
, 2011 The development of new drugs is one strategy for malaria control. Biochemical pathways localised in the apicoplast of the parasite, such as the synthesis of isoprenic precursors, are excellent targets because they are different or absent in the human ...
JORDÃO, Fabiana Morandi +2 more
core +3 more sources
eJHaem, Volume 7, Issue 1, February 2026.ABSTRACT Background Myeloma bone disease (MBD) is a devastating complication of multiple myeloma (MM) and a primary cause of disability in affected patients. Its pathogenesis is driven by an imbalance in bone remodeling, largely attributed to the overexpression of C‐C motif chemokine ligand 3 (CCL3). While both bortezomib and statins have been reported
Fujun Qu +6 more
wiley +1 more source
Uso de estatinas e o risco de Diabetes Mellitus tipo 2: Revisão Baseada na Evidência
Revista Brasileira de Medicina de Família e Comunidade, 2016 Objetivo: Determinar se existe relação entre o uso de estatinas e a incidência de Diabetes Melittus tipo 2 (DM2). Métodos: Foram realizadas pesquisas nas bases de dados National Guidelines Clearinghouse, Cochrane Lybrary, Trip database, PubMed e MedLine ...
Susana Silva, Nuno Monteiro
doaj +1 more source
Statins and selective inhibition of Rho kinase protect small conductance calcium-activated potassium channel function (KCa2.3) in cerebral arteries [PDF]
, 2012 Background: In rat middle cerebral and mesenteric arteries the KCa2.3 component of endothelium-dependent hyperpolarization (EDH) is lost following stimulation of thromboxane (TP) receptors, an effect that may contribute to the endothelial dysfunction ...
Alister J. McNeish +4 more
core +4 more sources
Statin-Associated Muscle Adverse Events : Update for clinicians
Sultan Qaboos University Medical Journal, 2016 Statins are potent medications which reduce low-density lipoprotein cholesterol (LDL-C) levels. Their efficacy in cardiovascular risk reduction is well established and indications for their use are expanding.
Maha A. Al-Mohaissen +3 more
doaj +1 more source