Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis [PDF]
BackgroundEzetimibe-statin combination therapy has been found to reduce low density lipoprotein cholesterol levels and the risk of major adverse cardiovascular events (MACEs) in large trials.
Namki Hong +13 more
doaj +1 more source
Effect of statin use on outcomes of adults with candidemia [PDF]
Background: Statins have immunomodulatory properties and hinder Candida growth. However, it is unknown whether they may improve prognosis in patients with candidemia.
Ayats, Josefina +11 more
core +1 more source
Convergent Metabolic Pathways in MASH Therapeutics: An AMPK‐Centric Analysis
ABSTRACT Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of liver‐related morbidity driven by systemic metabolic dysregulation. The recent approval of resmetirom and the clinical success of GLP‐1 receptor agonists have heralded a new era in MASH therapy, yet a convergent understanding of the complex mechanisms of these ...
Seungchan Choi +7 more
wiley +1 more source
Spielen Statine eine Rolle als adjuvante Therapie bei Entzündung? / Do statins play a role as an adjuvant therapy in inflammation? [PDF]
Despite recent advances in management of patients in intensive care units, sepsis and septic shock are the major causes of morbidity and mortality. Prompt and adequate antibiotic therapy accompanied by surgical removal of the infectious material are the ...
Almog +83 more
core +1 more source
Effect of Ceiling Fans on Core Temperature in Bed‐Resting Older Adults Exposed to Indoor Overheating
ABSTRACT Background Rising global temperatures have increased indoor overheating risks, posing significant health threats to vulnerable populations, particularly older adults. While electric fans are recommended for cooling at temperatures up to 40°C, the efficacy of ceiling fans in very warm indoor temperatures (~31°C) remains understudied.
Fergus K. O'Connor +6 more
wiley +1 more source
From flavors and pharmaceuticals to advanced biofuels: Production of isoprenoids in Saccharomyces cerevisiae [PDF]
Isoprenoids denote the largest group of chemicals in the plant kingdom and are employed for a wide range of applications in the food and pharmaceutical industry.
Ajikumar +70 more
core +2 more sources
Risk Factors for Cardiovascular and Metabolic Disease: Integrating Traditional and Novel Paradigms
ABSTRACT Cardiovascular and metabolic diseases (CVMD), encompassing atherosclerotic cardiovascular disease (ASCVD), heart failure, obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD), remain the leading global cause of morbidity and mortality.
Zhihua Wang +3 more
wiley +1 more source
Type I and type III collagen immunoexpression in rabbit skin biopsy samples treated with rosuvastatin gel and autologous platelet-rich plasma [PDF]
Purpose: To evaluate whether the joint use of autologous platelet-rich plasma (aPRP) and rosuvastatin (RSV) in biopsies of dermal wounds induced in rabbits results in an additive effect on the immunoexpression of collagens type I and III, optimizing the ...
Cristoffer da Silva Santana +7 more
doaj +1 more source
Background We analyzed the effect of statins in patients with hormone receptor‐positive (HR+) metastatic breast cancer treated with everolimus + exemestane (EverX).
Kyoungmin Lee +6 more
doaj +1 more source
Statins for primary and secondary prevention in the oldest old : an overview of the existing evidence [PDF]
Hypercholesterolemia, although a modifiable risk factor for cardiovascular disease, is still one of the leading causes of death among older people in western countries.
Petrovic, Mirko +2 more
core +1 more source

