Results 71 to 80 of about 6,933 (234)

Exploiting Pharmacokinetic/Pharmacodynamic Methods for Optimizing and Accelerating Drug Development of Innovative Anti‐Infectives

ChemMedChem, Volume 21, Issue 2, January 2026.
This article focuses on the interplay of absorbed, distributed, metabolized, and excreted (ADME) properties; in vivo pharmacokinetics (PK); and pharmacodynamics (PD) supported by in silico PK/PD modeling techniques to improve drug development by acceleration of processes and reducing attrition risks.
Katharina Rox
wiley   +1 more source

Karyotyping and Distribution Patterns of Endemic Chinese Lilies: Insights Into Their Conservation Under Climate Change

Ecology and Evolution, Volume 16, Issue 1, January 2026.
This study integrates cytogenetic and ecological analyses of two endemic Chinese alpine lilies, Lilium lophophorum (2n = 24) and L. nanum (2n = 48), to establish a foundational understanding of their chromosomal diversity and distribution patterns. We document substantial intraspecific karyotypic variation in diploid L.
Tengfei Gui, Mingyue Lin, Zhiming Li, Deli Peng, Yuan Huang, Wenguang Sun   +5 more
wiley   +1 more source

Synthesis , Antibacterial Activity of Sm(III) Complex With L-phenylalanine

Zanco Journal of Pure and Applied Sciences, 2022
      Samarium–amino acid complex in aqueous solution was synthesized in formula:[Sm(phen)3].H2O, by reaction of  L-phenylalanine (phen) with samarium chloride hexahydrate (SmCl3.6H2O) in (1:3) M:L mole ratio .
Kamaran Basheer Hussein
doaj  

Hedysarum langranii sp. nov. (Fabaceae, Hedysareae), a New Species From China, and Supplementary Descriptions of H. smithianum and H. dentatoalatum

Ecology and Evolution, Volume 16, Issue 1, January 2026.
Hedysarum langranii sp. nov. (Fabaceae, Hedysareae) is described from China based on morphological and phylogenetic evidence. Supplementary morphological descriptions of H. smithianum and H. dentatoalatum are provided. ABSTRACT Hedysarum langranii sp. nov. (Fabaceae, Hedysareae) is described and illustrated from Shaanxi, Henan and Gansu, China.
Pei‐Liang Liu, Yong‐Xing Qin, Lu‐Lu Xun, Bin Li, Yuan Lu, Ming Yue   +5 more
wiley   +1 more source

Revised phylogeny of the Inula complex group (Asteraceae: Inuleae) with a recircumscription of Carpesium and establishment of a new genus Cladocarpesium

Journal of Systematics and Evolution, Volume 64, Issue 1, Page 95-105, January 2026.
Cladocarpesium T. Deng & Qun Liu, gen. nov. (separated from Carpesium) is established with Cladocarpesium abrotanoides (L.) T. Deng & Qun Liu designated as the type species. The new genus is morphologically distinguished from Carpesium s.str. by its sympodial growth form (typically producing three branches), sessile capitula, and three‐seriate ...
Qun Liu, Nan Lin, Dai‐Gui Zhang, Xian‐Han Huang, Yan‐Bo Li, Ying‐Ying Zheng, Umida Tojiboeva, Jian‐Wen Zhang, Tao Deng   +8 more
wiley   +1 more source

Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease [PDF]

, 2016
Parkinson's disease (PD) is the most common neurodegenerative movement disorder, yet disease-modifying treatments do not currently exist. Rho-associated protein kinase (ROCK) was recently described as a novel neuroprotective target in PD.
Hagen Walle, Jan C. Koch, Katrin Eckermann, Lars Tatenhorst, Lars Tönges, Luis Fonseca-Ornelas, Markus Zweckstetter, Mathias Bähr, Paul Lingor, Stefan Becker, Tiago F. Outeiro, Tomás Lopes da Fonseca, Vivian Dambeck   +12 more
core   +3 more sources

Generation and plant production of recombinant fluorescent immunoglobulin G as innovative immunodiagnostic reagents

Plant Biotechnology Journal, Volume 24, Issue 1, Page 300-312, January 2026.
Summary Immunodiagnostic systems for on‐site screening are increasingly in demand but require expensive reagents such as chemically modified antibodies. To obtain biomolecules as ready‐to‐use reagents for diagnostics, new recombinant fluorescent immunoglobulins G were generated by fusion of the heavy chain of a monoclonal antibody, 5H3, to two ...
Ramona Sterpa, Marcello Catellani, Patrizia Melpignano, Thea Serra, Laura Anfossi, Cristina Capodicasa   +5 more
wiley   +1 more source

Covalent Organic Frameworks for Photocatalysis

Advanced Materials, Volume 37, Issue 52, December 29, 2025.
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra, Akhtar Alam, Avanti Chakraborty, Bidhan Kumbhakar, Samrat Ghosh, Pradip Pachfule, Arne Thomas   +6 more
wiley   +1 more source

8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications

Drug Design, Development and Therapy, 2013
Veda Prachayasittikul,1 Supaluk Prachayasittikul,2 Somsak Ruchirawat,3 Virapong Prachayasittikul11Department of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, 2Center of Data Mining and Biomedical Informatics, Faculty of ...
Prachayasittikul V, Prachayasittikul S, Ruchirawat S, Prachayasittikul V   +3 more
doaj  

PH and Electrochemical Responsive Materials for Corrosion Smart Coating Applications [PDF]

, 2008
Corrosion is a costly issue for military operations and civil industries. While most corrosion initiates from localized corrosion form, such as pitting, failure directly caused by localized corrosion is the most dangerous kind, because it is difficult to
Calle, Luz M., Li, Wenyan
core   +1 more source