Ultrasound-assisted extraction of scopolamine and hyoscyamine from Hyoscyamus niger roots using central compost design [PDF]
HeliyonHyoscyamus niger is an important medicinal plant used in medicine and contains tropane alkaloid compounds such as hyoscyamine and scopolamine. In this study, after the selection of the solvent for extracting hyoscyamine and scopolamine, the central ...
Roghayeh Ahmadpour +4 more
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Metabolic Effects of Elicitors on the Biosynthesis of Tropane Alkaloids in Medicinal Plants [PDF]
Plants, 2023 Tropane alkaloids (TAs) are large secondary metabolite alkaloids that find extensive applications in the synthesis of antidotes, anesthetics, antiemetics, motion sickness drugs, and antispasmodics.
Yuru Wen +5 more
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Bioorganic Chemistry, Toxinology, and Pharmaceutical Uses of Datura Metabolites and Derivatives [PDF]
ToxinsDatura species have been recognized for their potent pharmacological properties, producing a diverse array of tropane and non-tropane alkaloids with significant clinical and toxicological relevance.
Amin Mahmood Thawabteh +6 more
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Chitosan nanoparticles as a strategy for enhancing h6h gene expression and tropane alkaloid production in Hyoscyamus reticulatus hairy roots [PDF]
Scientific ReportsHyoscyamus reticulatus L. is a rich source of tropane alkaloids (TA) which is widely used in medicine. In this study, hairy roots were obtained from two-week cotyledon explants of H. reticulatus L. by using the A7 strain of Agrobacterium rhizogenes.
Raheleh Godsi +2 more
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Modeling the functionalized genistein-hyoscyamine derivatives [PDF]
Scientific ReportsDue to the significant rise in demand for functional foods and health-conscious alternatives, natural extracts present a promising avenue for exploration and application within the food processing sector.
Rana Abd-ElSalam +2 more
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The high production of tropane alkaloids in hairy roots of Hyoscyamus reticulatus L. elicited by ZnO NPs in a bioreactor condition [PDF]
Scientific ReportsChemical synthesis issue of tropane alkaloids and their lowest production rate along with their extraction costs has made use of new methods necessary to produce valuable pharmaceutical compounds.
Sahar Alizadeh +3 more
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Modulation of Tropane Alkaloids’ Biosynthesis and Gene Expression by Methyl Jasmonate in Datura stramonium L.: A Comparative Analysis of Scopolamine, Atropine, and Hyoscyamine Accumulation [PDF]
LifeScopolamine and atropine are two medicinal alkaloids derived from Datura stramonium L. with anticholinergic properties. This study explored how methyl jasmonate (MJ), a plant growth regulator, affects the biosynthesis and accumulation of these alkaloids ...
Arash Rasi +4 more
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Management of Treatment and Prevention of Acute OP Pesticide Poisoning by Medical Informatics, Telemedicine and Nanomedicine [PDF]
International Journal Bioautomation, 2013 Acute organophosphorous pesticide (OP) poisoning kills a lot of people each year. Treatment of acute OP poisoning is of very difficult task and is a time taking event.
Ganesh Chandra Sahoo +13 more
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Elicitation of Hyoscyamine Production in Datura stramonium L. Plants Using Tobamoviruses
Plants, 2022 Datura stramonium L. produces tropane alkaloids, and the hyoscyamine is dominant among them. Hyoscyamine is produced by hairy root cultures in vitro derived from native plants or plants with the genetically modified biosynthetic pathway for hyoscyamine ...
Daniel Mihálik +4 more
doaj +1 more source
Effect of saccharides on secondary compounds production from stem derived callus of Datura inoxia
Biotechnology Reports, 2022 Datura inoxia is a subshrub plant known for its toxicity which results from the presence of the tropane alkaloid scopolamine and hyoscyamine. Saccharides are one of the most important elicitors that can alter physiological and biochemical responses in ...
Baan Munim Twaij +3 more
doaj +1 more source