Pyridostigmine Induced Prolonged Asystole in a Patient with Myasthenia Gravis Successfully Treated with Hyoscyamine [PDF]
Case Reports in Cardiology, 2017 Reversible acetylcholinesterase inhibitors are used as first-line treatment for myasthenia gravis. They improve symptoms by increasing concentration of acetylcholine at the neuromuscular junction and stimulating nicotinic receptors.
Mohammad Saud Khan +5 more
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Expression of
Microbial Cell Factories, 2008 Background Tropane alkaloids, mainly hyoscyamine and scopolamine, are widely used in medicine due to their anticholinergic activity. Scopolamine has a higher demand being the more valuable alkaloid due to its fewer side effects and higher physiological ...
Giulietti Ana M +2 more
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Biotechnologie, Agronomie, Société et Environnement, 2016 Description of the subject. The hyoscyamine, a tropane alkaloid, widely used in medicine, can be produced from Datura sp. (Solanaceae). However, its content in the spontaneous roots remains low; therefore, hairy roots (HRs) were envisaged as a potential ...
Belabbassi, O. +7 more
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Essai de culture du Datura innoxia au Burkina Faso : évolution des teneurs en hyoscyne et hyoscyamine au cours de la croissance [PDF]
Tropicultura, 1986 Cultivation attempt of Datura innoxia in Burkina Faso : hyoscyne and hyoscyamine content evolution during plant development. This paper presents the basic principles for an exploitation of Datura innoxia in the hyoscyne and hyoscyamine alkaloids ...
Dame, C. +7 more
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The biosynthesis of the tropane alkaloid hyoscyamine in datura stramonium [PDF]
, 1999 This thesis investigates the biosynthesis of the tropane alkaloid hyoscyamine in Datura stramonium. The biosynthesis of the medicinally important tropane alkaloid hyoscyamine has been investigated for many years.
Wong, Chi W.
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Rational Design of Hyoscyamine 6β-Hydroxylase for the Efficient Production of Scopolamine. [PDF]
Plant Biotechnol JPlant Biotechnology Journal, Volume 24, Issue 5, Page 3368-3370, May 2026.
Meng Y +10 more
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Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole-Cell Factory Saccharomyces Cerevisae. [PDF]
ChembiochemThis review highlights advances in engineering Saccharomyces cerevisiae for the sustainable biocatalytic production of pharmaceutically relevant amines, amino alcohols, amino acids, and complex alkaloids. It focuses on strategies to increase productivity, including enhanced enzyme expression, cofactor regeneration, precursor channeling, pathway ...
Kwiatos N, Ossel S, Mutti FG.
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The Blue Delirium: Serotonin and Anticholinergic Toxicity in a 95-Year-Old Woman. [PDF]
J Am Geriatr SocJournal of the American Geriatrics Society, Volume 74, Issue 7, Page 2158-2160, July 2026.
Badell CS +3 more
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ON THE ADMINISTRATION OF HYOSCYAMINE. [PDF]
The Lancet, 1878 n ...
Lawson, R., Chubb, CharlesWm
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Metabolic Effects of Elicitors on the Biosynthesis of Tropane Alkaloids in Medicinal Plants
Plants, 2023 Tropane alkaloids (TAs) are large secondary metabolite alkaloids that find extensive applications in the synthesis of antidotes, anesthetics, antiemetics, motion sickness drugs, and antispasmodics.
Yuru Wen +5 more
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