Rational Design of Hyoscyamine 6β-Hydroxylase for the Efficient Production of Scopolamine. [PDF]
Plant Biotechnol JPlant Biotechnology Journal, Volume 24, Issue 5, Page 3368-3370, May 2026.
Meng Y +10 more
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Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole-Cell Factory Saccharomyces Cerevisae. [PDF]
ChembiochemThis review highlights advances in engineering Saccharomyces cerevisiae for the sustainable biocatalytic production of pharmaceutically relevant amines, amino alcohols, amino acids, and complex alkaloids. It focuses on strategies to increase productivity, including enhanced enzyme expression, cofactor regeneration, precursor channeling, pathway ...
Kwiatos N, Ossel S, Mutti FG.
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Scopolia carniolica var. hladnikiana: Alkaloidal Analysis and Potential Taxonomical Implications
Plants, 2021 The present research sought to compare the content of hyoscyamine/atropine and scopolamine in Scopolia carniolica and its contested variety, S. carniolica var. hladnikiana, with the aim of investigating differences that may be of taxonomical significance.
Karsten Fatur +2 more
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ON THE ADMINISTRATION OF HYOSCYAMINE. [PDF]
The Lancet, 1878 n ...
Lawson, R., Chubb, CharlesWm
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A Case of Belladonna Poisoning With Late-Onset Reappearance of Anticholinergic Toxicity. [PDF]
Clin Case RepOn day 1, blood concentrations of atropine and scopolamine were extremely low, whereas urinary concentrations were elevated, suggesting rapid urinary excretion. Subsequently, urinary concentrations decreased; however, at symptom recurrence, the blood atropine concentration increased, suggesting redistribution into the bloodstream. ABSTRACT In a patient
Hayashi T +9 more
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Identification of Tropane Alkaloid Chemotypes and Genotypes in Hyoscyamus niger L.
Journal of the American Society for Horticultural Science, 2023 Tropane alkaloids (TA) are compounds widespread in the Solanaceae family. The genera Atropa, Brugmansia, Hyoscyamus, and Scopolia, produce the pharmaceuticals hyoscyamine (Hy) and scopolamine (Sc), which are valued for their antimuscarinic and ...
Lawrence Kramer +3 more
doaj +1 more source
Influence of different Agrobacterium rhizogenes strains on hairy roots induction and secondary metabolites production in Datura innoxia Mill. [PDF]
Journal of Medicinal Plants, 2022 Background: Datura innoxia Mill. is one of the medicinal plant which can produce tropan alkaloids such as hyoscyamine and scopolamine with analgesic and antiasthmatic activities.
Parisa Naderian +3 more
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EVALUATION OF SOME GROWTH CHARACTERS AND ALKALOID PRODUCTIVITY OF DIPLOIDY AND TETRAPLOIDY FORMS OF Datura stramonium AND Datura innoxia PLANTS [PDF]
Journal of Soil Sciences and Agricultural Engineering, 2004 Field experiment was conducted to study the diversity in growth parameters and alkaloid production between diploidy and tetra ploidy levels of Datura stramonium and Datura innoxia plants. Increases in plant height.
A. A. Youssef +2 more
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Evaluation of Changes in Alkaloid Content and some Physiological Traits of Datura stramonium L. under the Influence of Planting Date and Plant Density Levels [PDF]
Majallah-i ̒Ulum-i Bāghbānī, 2022 Introduction Datura stramonium L. is one of the medicinal plants that have a special role in the pharmaceutical industry due to its alkaloid compounds.
Z. Izadi +4 more
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Microbial Cell Factories, 2008 Background Tropane alkaloids, mainly hyoscyamine and scopolamine, are widely used in medicine due to their anticholinergic activity. Scopolamine has a higher demand being the more valuable alkaloid due to its fewer side effects and higher physiological ...
Giulietti Ana M +2 more
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