A Case of Belladonna Poisoning With Late-Onset Reappearance of Anticholinergic Toxicity. [PDF]
Clin Case RepOn day 1, blood concentrations of atropine and scopolamine were extremely low, whereas urinary concentrations were elevated, suggesting rapid urinary excretion. Subsequently, urinary concentrations decreased; however, at symptom recurrence, the blood atropine concentration increased, suggesting redistribution into the bloodstream. ABSTRACT In a patient
Hayashi T +9 more
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Scopolia carniolica var. hladnikiana: Alkaloidal Analysis and Potential Taxonomical Implications
Plants, 2021 The present research sought to compare the content of hyoscyamine/atropine and scopolamine in Scopolia carniolica and its contested variety, S. carniolica var. hladnikiana, with the aim of investigating differences that may be of taxonomical significance.
Karsten Fatur +2 more
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Identification of Tropane Alkaloid Chemotypes and Genotypes in Hyoscyamus niger L.
Journal of the American Society for Horticultural Science, 2023 Tropane alkaloids (TA) are compounds widespread in the Solanaceae family. The genera Atropa, Brugmansia, Hyoscyamus, and Scopolia, produce the pharmaceuticals hyoscyamine (Hy) and scopolamine (Sc), which are valued for their antimuscarinic and ...
Lawrence Kramer +3 more
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Evaluation of Changes in Alkaloid Content and some Physiological Traits of Datura stramonium L. under the Influence of Planting Date and Plant Density Levels [PDF]
Majallah-i ̒Ulum-i Bāghbānī, 2022 Introduction Datura stramonium L. is one of the medicinal plants that have a special role in the pharmaceutical industry due to its alkaloid compounds.
Z. Izadi +4 more
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Application of recombinant DNA technology to studies on plant secondary metabolism [PDF]
, 2001 This review which is concerned with the application of recombinant DNA technology to studies on plant secondary metabolism, presents the more common plant transformation strategies and shows how these genetic approaches are being used in attempts to ...
Yeoman, Michael M., Zárate, Rafael
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Enhanced production of tropane alkaloids in transgenic Scopolia parviflora hairy root cultures over-expressing putrescine N-methyl transferase (PMT) and hyoscyamine-6β-hydroxylase (H6H) [PDF]
, 2011 Scopolia parviflora adventitious roots were metabolically engineered by co-expression of the two gene putrescine N-methyl transferase (PMT) and hyoscyamine-6β-hydroxylase (H6H) cDNAs with the aid of Agrobacterium rhizogenes.
Choi, M.S. +8 more
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Production of tropane alkaloids in Hyoscyamus niger (black henbane) hairy roots grown in bubble-column and spray bioreactors [PDF]
, 2013 Hairy root cultures of Hyoscyamus niger were cultivated in shake-flasks, a bubble-column bioreactor and a hybrid bubble-column/spray bioreactor and evaluated for alkaloid production.
Adam Kokotkiewicz +4 more
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Global Biosecurity, 2023 In December 2022 a large outbreak of anti-cholinergic toxidrome was reported in Australia associated with contamination of baby spinach leaves with Datura stramonium. Over 100 individuals around Australia experienced symptoms consistent with intoxication
David Heslop
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Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium [PDF]
E3S Web of Conferences, 2021 The alkaloid extract of datura stramonium (rich of atropine, hyoscyamine, scopolamine) is used to evaluate its effect on the central nervous system in rats (locomotion, anxiety).
Didou Latifa +5 more
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Microbial Cell Factories, 2008 Background Tropane alkaloids, mainly hyoscyamine and scopolamine, are widely used in medicine due to their anticholinergic activity. Scopolamine has a higher demand being the more valuable alkaloid due to its fewer side effects and higher physiological ...
Giulietti Ana M +2 more
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