Results 31 to 40 of about 2,294 (167)
Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition. [PDF]
ImmunologyMevalonate pathway is important for the effector function of gammadelta T cells. Inhibition of the pathway in vivo and in vitro impairs cytokine and cytotoxic molecule production by mainly affecting protein prenylation and disturbing intracellular signalling in Vdelta2 T cells. Created with Biorender.
Suen TK +14 more
europepmc +2 more sources
, 2022 Hidradenitis Suppurativa (HS) is a chronic suppurative disease of the pilosebaceous unit. The current model of HS pathophysiology describes the condition as the product of hyperkeratinisation and inflammation at the hair follicular unit.
Agnes Duquesne (12755411) +6 more
core +1 more source
Febre periódica: síndroma hiper-IgD--primeiro caso em Portugal.
Acta Médica Portuguesa, 2004 Periodic fever can have one of multiple causes. Among the hereditary periodic fever syndromes, hyper-IgD syndrome (HIDS) is a possible diagnosis, although, until now, no cases had been described in Portugal.We report a 25-year-old woman, with periodic ...
Tiago Tribolet de Abreu
doaj +1 more source
Long-term fever in a child: what is the reason, how to examine, treat or not treat?
Медицинский совет, 2020 Long unclear fever in children of different ages remains one of the difficult and topical issues in the paediatric practice. Despite up-to-date techniques of laboratory and instrumental examination, verification of prolonged fever causes remains ...
I. N. Zakharova +6 more
doaj +1 more source
Autoinflammatory Syndromes in the Practice of Pediatrician
Zdorovʹe Rebenka, 2014 В обзорной статье предоставлены информация, характеристика, определение и классификация заболеваний, которые были отнесены к отдельной нозологической группе и названы аутовоспалительными заболеваниями или синдромами (АВС).
S.N. Nedelskaya +3 more
doaj +1 more source
Frontiers in Pediatrics, 2017 Mevalonate kinase deficiency impairs several aspects of the patient’s quality of life, thus early diagnosis and treatment are required to improve health-related quality of life (HRQOL).
Gianluigi Laccetta +3 more
doaj +1 more source
Hyper IgD syndrome and type AA amyloidosis. [PDF]
, 2009 Contains fulltext : 80421.pdf (Publisher’s version ) (Open Access)
Hilst, J.C.H. van der
openaire +2 more sources
Pediatric Rheumatology Online Journal, 2020 Background Rare autoinflammatory diseases (AIDs) including Cryopyrin-Associated Periodic Syndrome (CAPS), Tumor Necrosis Receptor-Associated Periodic Syndrome (TRAPS) and Mevalonate Kinase Deficiency Syndrome (MKD)/ Hyper-IgD Syndrome (HIDS) are ...
Sandra Hansmann +11 more
doaj +1 more source
Allergy, EarlyView.ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier +221 more
wiley +1 more source
JCC Plus, Volume 1, Issue 4, July 2026.ABSTRACT Background Low‐dose thiopurine therapy in combination with allopurinol (LD‐THIO/ALLO) is a widely used treatment for inflammatory bowel disease (IBD). However, little is known about the effects of in utero exposure to this combination on pregnancy and birth outcomes.
Kavitha Sivananthan +9 more
wiley +1 more source