Results 211 to 220 of about 84,168 (327)

Effects of Substance P Antagonist, [D-Arg, D-Phe, D-Trp, Leu]- Substance P on the Mechanical Hyperalgesia of Inflammation Induced by Freund's Complete Adjuvant in Rat Paw [PDF]

open access: green, 2000
Min Kyung Kim   +7 more
openalex   +1 more source

Pain and Sedative Medication Use Among Individuals With Inflammatory Bowel Disease: A Nationwide Population‐Based Cohort Study

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 7, Page 732-742, October 2025.
Over 20% of individuals with IBD were prescribed pain or sedative medications annually, with rising chronic and co‐prescribing rates. Risk factors included female sex, older age, Crohn's disease, and mental health conditions. Targeted interventions are needed to reduce harmful prescribing and promote safer alternatives.
Samantha Baillie   +6 more
wiley   +1 more source

Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4466-4489, October 2025.
Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota   +4 more
wiley   +1 more source

Pain Perception and Modulation: Fundamental Neurobiology and Recent Advances

open access: yesEuropean Journal of Neuroscience, Volume 62, Issue 8, October 2025.
Chronic pain is a major burden with variable treatment responses reflecting complex biopsychosocial and neurobiological factors. This narrative review synthesizes evidence on neural structures, circuits, and mediators involved in pain perception and modulation.
Willem W. J. van Strien   +1 more
wiley   +1 more source

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