Results 71 to 80 of about 104,030 (296)

Opioid-induced hyperalgesia: pain hurts? [PDF]

open access: yesBritish Journal of Anaesthesia, 2010
In the current issue of the British Journal of Anaesthesia, Shin and colleagues report that propofol used for the maintenance of general anaesthesia may prevent remifentanilinduced hyperalgesia. In their study, a comparison of propofol and sevoflurane combined with either high dose or low dose of remifentanil for the maintenance of general anaesthesia ...
Konopka, K-H., van Wijhe, M.
openaire   +3 more sources

Review of the Performance of Quantitative Sensory Testing Methods to Detect Hyperalgesia in Chronic Pain Patients on Long-term Opioids

open access: yesAnesthesiology, 2015
Background:Opioid-induced hyperalgesia is a clinical syndrome whereby patients on long-term opioids become more sensitive to pain while taking opioids. Opioid-induced hyperalgesia is characterized by increased pain intensity over time, spreading of pain ...
Nathaniel Katz, F. Paillard, R. Edwards
semanticscholar   +1 more source

Traditional Chinese Medicine as an Integrative Adjunct in Oncology Perioperative Practice: Analgesia, Immune Modulation, and Translational Challenges

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Traditional Chinese medicine (TCM), including herbal analgesic adjuvants and acupuncture‐based interventions, has gained increasing attention as an integrative strategy for perioperative pain management in oncology. Bioactive phytochemicals—such as terpenoids, flavonoids, alkaloids, and polyphenols—exert multimodal pharmacological effects ...
Yuqin Tang   +5 more
wiley   +1 more source

Gene Network Dysregulation in the Trigeminal Ganglia and Nucleus Accumbens of a Model of Chronic Migraine-Associated Hyperalgesia

open access: yesFrontiers in Systems Neuroscience, 2018
The pharmacological agent nitroglycerin (NTG) elicits hyperalgesia and allodynia in mice. This model has been used to study the neurological disorder of trigeminovascular pain or migraine, a debilitating form of hyperalgesia.
Hyeonsoo Jeong   +10 more
doaj   +1 more source

Inter-strain differences of serotonergic inhibitory pain control in inbred mice [PDF]

open access: yes, 2010
Background: Descending inhibitory pain control contributes to the endogenous defense against chronic pain and involves noradrenergic and serotonergic systems.
Wijnvoord, Nina   +5 more
core   +2 more sources

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

How does observational learning produce placebo effects? : a model integrating research findings [PDF]

open access: yes, 2018
There is a growing body of evidence proving that observational learning, in addition to classical conditioning and verbal suggestions, may induce both placebo analgesia and nocebo hyperalgesia.
Bajcar, Elżbieta, Bąbel, Przemysław
core   +2 more sources

mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia

open access: yesMolecular Pain, 2015
Chronic pain is a major public health problem with limited treatment options. Opioids remain a routine treatment for chronic pain, but extended exposure to opioid therapy can produce opioid tolerance and hyperalgesia.
B. Lutz   +4 more
semanticscholar   +1 more source

Low‐Frequency Stimulation Provides Significant Added Benefit for Postpartum Urinary Incontinence: A Retrospective Cohort Study

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the clinical efficacy of low‐frequency electrical stimulation (LES) in treating UI among postpartum women. Methods Postpartum women diagnosed with UI who received treatment at two tertiary hospitals between 1st January and 30th June 2020 were included.
Yaxin Liang   +5 more
wiley   +1 more source

Correlation between Different Psychological Variables in Women with Fibromyalgia with Symptoms of Neurogenic Inflammation: A Cross-Sectional Study

open access: yesBiomedicines
Fibromyalgia (FM) is a chronic pain syndrome hypothesized to arise from a state of neurogenic inflammation. Mechanisms responsible for pain, as well as psychological variables, are typically altered in this condition.
Víctor Riquelme-Aguado   +5 more
doaj   +1 more source

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