Results 81 to 90 of about 16,227 (258)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The study aimed to compare the use of liposomal bupivacaine (LB) and ropivacaine hydrochloride (RH) in combined thoracic paravertebral block (TPVB) and serratus anterior plane block (SAPB) during video‐assisted thoracoscopic surgery (VATS).
Lu Jin, Lian Tang
wiley +1 more source
Ovariectomy-induced chronic abdominal hypernociception in rats: Relation with brain oxidative stress [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2015 Context: Ovarian hormone deficiency observed in menopausal women increases the production of reactive oxygen species, which could be implicated in central sensitization subjacent in chronic functional pain syndromes.
Bárbara B. Garrido-Suárez +5 more
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The study aimed to investigate the efficacy of ultrasound‐guided intercostal nerve block (ICNB) with liposomal bupivacaine (LB) comparing ropivacaine‐dexamethasone (RD) for treating postherpetic neuralgia (PHN) in adult patients. A total of 108 patients were randomized 1:1 to receive ICNB with LB or ICNB with RD.
Jin Li, Xiang‐Yu Fang
wiley +1 more source
Efeitos antinociceptivos da dipirona e seus principais metabólitos na nocicepção aguda e hiperalgesia mecânica induzidas por endotelina-1 na pata de camundongos [PDF]
, 2014 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.A dipirona foi introduzida na prática clínica em 1922.
Schroeder, Samilla Driessen
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Medicinal Research Reviews, EarlyView.ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu +15 more
wiley +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
Participação das endotelinas e seus receptores na neuralgia do trigêmeo: mecanismos operados em células do gânglio trigeminal [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2015.Este estudo avaliou a habilidade da endotelina-1 (ET-1) em promover hiperalgesia orofacial ao calor ...
Gomes, Lenyta Oliveira
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Primary and Secondary Hyperalgesia
, 2023 According to the definition of the International Association for the Study of Pain, hyperalgesia means "an excessive reaction to moderate nociceptive stimulation".
Lapasova Zebiniso Khidirovna
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Advances in research on layered double hydroxides for biomedical applications
Smart Molecules, EarlyView.Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Opioid-induced hyperalgesia [PDF]
, 2006 Recently it became clear that opioids, besides their role in analgesia, mayalso induce hyperalgesia. Something what in the past was called opioidneurotoxicity.
Mercadante, Sebastiano; Palliative Medicine, Department of Anaesthesia, Intensive Care and Emergency, University of Palermo, Italy
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