Results 101 to 110 of about 16,227 (258)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade +7 more
wiley +1 more source
Journal of Venomous Animals and Toxins including Tropical Diseases, 2011 A myotoxin phospholipase A2 homologue, BmooMtx, was isolated from the venom of Bothrops moojeni by a combination of ion-exchange chromatography on DEAE-Sephacel column and gel filtration on Sephadex G-75. SDS-PAGE showed the enzyme to be a monomer with a
MR Queiroz +9 more
doaj +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Analgesic effect of chronic oral administration of aerial part of Marrubium Vulgare in diabetic rats
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006 BACKGROUND AND OBJECTIVE: Considering the antidiabetic and anti-inflammatory effect of marrubium vulgare (MV), this study was designed to investigate the analgesic effect of MV on formalin-induced nociceptive response (standard formalin test) in diabetic
M Roghani,, T Balouch Nejad Mojarad
doaj
Sympathetic-Sensory Coupling as a Potential Mechanism for Acupoints Sensitization
Journal of Pain Research, 2023 Xiang Cui,1 Ziyi Zhang,1,2 Hanqing Xi,1 Kun Liu,1 Bing Zhu,1 Xinyan Gao1 1Department of Physiology, Institute of Acupuncture and Moxibustion, Academy of Chinese Medical Sciences, Beijing, 100700, People’s Republic of China; 2College of Acupuncture and ...
Cui X +5 more
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The Journal of Pain, 2004 Journal of Pain 5 (2004) S31-S31. doi:10.1016/j.jpain.2004.02.090 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:23:37 ; DOI:10.1016/j.jpain.2004.02.090 ; Page Range: S31 ...
University of Florida, Gainesville, FL USA ( host institution ) +8 more
openaire +2 more sources
British Journal of Pharmacology, EarlyView.Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux +26 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015 Background and Objectives:One of the common complications of diabetes is nervous system disorder and diabetic neuropathy. In various studies, it has been reported that flavonoid and polyphenolic compounds of plants improve diabetic neuropathy. Due to the
Omid Reza Tamtaji +2 more
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