ABSTRACT Background Posttraumatic stress disorder (PTSD) is highly comorbid with chronic pain. Yet, the effects of PTSD's seemingly opposing characteristics—hyperarousal and dissociation—on chronic pain are unclear. This study examined a moderated mediation model, accordingly (a) traumatic stress is associated with higher risk for chronic pain, through
Noga Gur +10 more
wiley +1 more source
Oromucosal Administration of a Cannabidiol-Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain. [PDF]
Campos RMP +5 more
europepmc +1 more source
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford +14 more
wiley +1 more source
Dose and parameter specific effects of curcumin on neuropathic pain, cavity formation, and non-coding RNA expression in a spinal cord injury model. [PDF]
Farazi MM +6 more
europepmc +1 more source
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu +3 more
wiley +1 more source
RETRACTED: Peritore et al. Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat. <i>Int. J. Mol. Sci.</i> 2020, <i>21</i>, 3509. [PDF]
Peritore AF +10 more
europepmc +1 more source
ABSTRACT Aims To evaluate the clinical efficacy of low‐frequency electrical stimulation (LES) in treating UI among postpartum women. Methods Postpartum women diagnosed with UI who received treatment at two tertiary hospitals between 1st January and 30th June 2020 were included.
Yaxin Liang +5 more
wiley +1 more source
Trajectories of Pain Processing in Recurrent Acute and Chronic Pancreatitis: A Longitudinal Quantitative Sensory Testing Study. [PDF]
Kuhlmann L +8 more
europepmc +1 more source
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli +8 more
wiley +1 more source
Unpredictable sound stress induces a novel form of hyperalgesic priming. [PDF]
Araldi D, Green PG, Levine JD.
europepmc +1 more source

